HLA‐DR‐expressing NK cells: Effective killers suspected for antigen presentation

Recurrent Stimulation of Natural Killer Cell Clones with K562 Expressing Membrane-Bound Interleukin-21 Affects Their Phenotype, Interferon-γ Production, and Lifespan

(2019) Maria Streltsova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human Cytomegalovirus Antigen Presentation by HLA-DR+ NKG2C+ Adaptive NK Cells Specifically Activates Polyfunctional Effector Memory CD4+ T Lymphocytes

(2019) Marcel Costa-García et al.   Frontiers in Immunology

Effect of IL-18 on the Expansion and Phenotype of Human Natural Killer Cells: Application to Cancer Immunotherapy

(2018) Hiroaki Senju et al.   International Journal of Biological Sciences

Expanded CD56superbrightCD16+ NK cells from ovarian cancer patients are cytotoxic against autologous tumor in a patient-derived xenograft murine model

(2018) Sophie M Poznanski et al.   Cancer Immunology Research

Initial results of two phase I trials delivering mbIL-21 ex vivo expanded haploidentical NK cells after fludarabine/cytarabine for patients with relapsed/refractory myeloid leukemias.

(2018) Stefan O. Ciurea et al.   JOURNAL OF CLINICAL ONCOLOGY

The Broad Spectrum of Human Natural Killer Cell Diversity

(2017) Aharon G. Freud et al.   IMMUNITY

HLA-DR+ NK cells are mostly characterized by less mature phenotype and high functional activity

(2017) Sofya A Erokhina et al.   IMMUNOLOGY AND CELL BIOLOGY

Influence of Irradiated Peripheral Blood Mononuclear Cells on Both Ex Vivo Proliferation of Human Natural Killer Cells and Change in Cellular Property

(2017) María Delso-Vallejo et al.   Frontiers in Immunology

CD2-CD58 interactions are pivotal for the activation and function of adaptive natural killer cells in human cytomegalovirus infection

(2016) Alexander Rölle et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-21–Induced MHC Class II+NK Cells Promote the Expansion of Human Uncommitted CD4+Central Memory T Cells in a Macrophage Migration Inhibitory Factor–Dependent Manner

(2016) Romain Loyon et al.   JOURNAL OF IMMUNOLOGY

Present Yourself! By MHC Class I and MHC Class II Molecules

(2016) Kenneth L. Rock et al.   TRENDS IN IMMUNOLOGY

Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium

(2016) Annette Pachnio et al.   PLoS Pathogens

Successful Interferon-Free Therapy of Chronic Hepatitis C Virus Infection Normalizes Natural Killer Cell Function

(2015) Elisavet Serti et al.   GASTROENTEROLOGY

Cutting Edge: Induction of Inflammatory Disease by Adoptive Transfer of an Atypical NK Cell Subset

(2015) Elisaveta Voynova et al.   JOURNAL OF IMMUNOLOGY

Expansion of an Atypical NK Cell Subset in Mouse Models of Systemic Lupus Erythematosus

(2015) Elisaveta N. Voynova et al.   JOURNAL OF IMMUNOLOGY

Impaired natural killer cell responses are associated with loss of the highly activated NKG2A+CD57+CD56dim subset in HIV-1 subtype D infection in Uganda

(2014) Prossy Naluyima et al.   AIDS

NK Cells and Their Ability to Modulate T Cells during Virus Infections

(2014) Kevin D. Cook et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Natural killer and dendritic cells collaborate in the immune response induced by the vaccine against uterine cervical cancer

(2014) Inge Langers et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Growth and Activation of Natural Killer Cells Ex Vivo from Children with Neuroblastoma for Adoptive Cell Therapy

(2013) Y. Liu et al.   CLINICAL CANCER RESEARCH

Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation

(2013) F. Marras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Priming of NK Cell Anti-Viral Effector Mechanisms by Direct Recognition of Human Cytomegalovirus

(2013) Aura Muntasell et al.   Frontiers in Immunology

Phase I clinical trial combining imatinib mesylate and IL-2

(2013) Nathalie Chaput et al.   OncoImmunology

Virologically Suppressed HIV Patients Show Activation of NK Cells and Persistent Innate Immune Activation

(2012) G. F. Lichtfuss et al.   JOURNAL OF IMMUNOLOGY

Herpes Simplex Virus Antigens Directly Activate NK Cells via TLR2, Thus Facilitating Their Presentation to CD4 T Lymphocytes

(2012) M. Kim et al.   JOURNAL OF IMMUNOLOGY

Membrane-Bound IL-21 Promotes Sustained Ex Vivo Proliferation of Human Natural Killer Cells

(2012) Cecele J. Denman et al.   PLoS One

A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG

(2011) J. Henry Evans et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection

(2011) S. Lopez-Verges et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural killer (NK)-dendritic cell interactions generate MHC class II-dressed NK cells that regulate CD4+ T cells

(2011) M. Nakayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD56bright NK cells after hematopoietic stem cell transplantation are activated mature NK cells that expand in patients with low numbers of T cells

(2010) Marija Vukicevic et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activating and inhibitory receptors of natural killer cells

(2010) Hollie J Pegram et al.   IMMUNOLOGY AND CELL BIOLOGY

A novel population of human CD56+human leucocyte antigen D-related (HLA-DR+) colonic lamina propria cells is associated with inflammation in ulcerative colitis

(2009) S. C. Ng et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Differential upregulation of chemokine receptors on CD56+NK cells and their transmigration to the site of infection in tuberculous pleurisy

(2009) Supriya Pokkali et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Human NK Cell Up-regulation of CD69, HLA-DR, Interferon γ Secretion and Cytotoxic Activity by Plasmacytoid Dendritic Cells is Regulated through Overlapping but Different Pathways

(2009) Adel Benlahrech et al.   SENSORS

Human natural killer cells

(2008) M. A. Caligiuri   BLOOD

Natural killer cells infiltrating human nonsmall-cell lung cancer are enriched in CD56brightCD16− cells and display an impaired capability to kill tumor cells

(2008) Paolo Carrega et al.   CANCER

Circulating HLA-DR+ natural killer cells have potent lytic ability and weak antigen-presenting cell function

(2008) Bryan M. Burt et al.   HUMAN IMMUNOLOGY