Fermentable Dietary Fiber Promotes Helminth Infection and Exacerbates Host Inflammatory Responses

Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation

(2019) Vishal Singh et al.   GUT

Exclusive dependence of IL-10Rα signalling on intestinal microbiota homeostasis and control of whipworm infection

(2019) María A. Duque-Correa et al.   PLoS Pathogens

Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health

(2018) Jun Zou et al.   Cell Host & Microbe

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

(2018) Bjoern O. Schroeder et al.   Cell Host & Microbe

Have you tried spermine? A rapid and cost-effective method to eliminate dextran sodium sulfate inhibition of PCR and RT-PCR

(2018) Łukasz Krych et al.   JOURNAL OF MICROBIOLOGICAL METHODS

The impact of a helminth-modified microbiome on host immunity

(2018) Tara P. Brosschot et al.   Mucosal Immunology

Sex and strain dependent differences in mucosal immunology and microbiota composition in mice

(2018) Marlies Elderman et al.   Biology of Sex Differences

Manipulation of host and parasite microbiotas: Survival strategies during chronic nematode infection

(2018) Emily C. White et al.   Science Advances

Feeding a Diet Containing a Fructooligosaccharide Mix Can Enhance Salmonella Vaccine Efficacy in Mice

(2018) Jalil Benyacoub et al.   JOURNAL OF NUTRITION

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

(2018) Vishal Singh et al.   CELL

The prebiotic inulin modulates gut microbiota but does not ameliorate atherosclerosis in hypercholesterolemic APOE*3-Leiden.CETP mice

(2018) Lisa R. Hoving et al.   Scientific Reports

Mucosal Barrier and Th2 Immune Responses Are Enhanced by Dietary Inulin in Pigs Infected With Trichuris suis

(2018) Laura J. Myhill et al.   Frontiers in Immunology

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction

(2017) Emilie Catry et al.   GUT

Supplementation of Low- and High-fat Diets with Fermentable Fiber Exacerbates Severity of DSS-induced Acute Colitis

(2017) Jennifer P. Miles et al.   INFLAMMATORY BOWEL DISEASES

Specific inulin-type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function, and microbiota homeostasis

(2017) Kang Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The role of IL-12/23 in T cell–related chronic inflammation: implications of immunodeficiency and therapeutic blockade

(2017) Anna Schurich et al.   RHEUMATOLOGY

Th2 and Th1 Responses: Clear and Hidden Sides of Immunity Against Intestinal Helminths

(2017) Alba Cortés et al.   TRENDS IN PARASITOLOGY

β2→1-Fructans Modulate the Immune System In Vivo in a Microbiota-Dependent and -Independent Fashion

(2017) Floris Fransen et al.   Frontiers in Immunology

Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety

(2017) Lucy Brooks et al.   Molecular Metabolism

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Nondigestible Fructans Alter Gastrointestinal Barrier Function, Gene Expression, Histomorphology, and the Microbiota Profiles of Diet-Induced Obese C57BL/6J Mice

(2016) Tzu-Wen Liu et al.   JOURNAL OF NUTRITION

Mucosal and systemic immune modulation byTrichuris trichiurain a self-infected individual

(2016) A. Dige et al.   PARASITE IMMUNOLOGY

Prebiotic inulin supplementation modulates the immune response and restores gut morphology in Giardia duodenalis-infected malnourished mice

(2016) Geeta Shukla et al.   PARASITOLOGY RESEARCH

Helminth infection promotes colonization resistance via type 2 immunity

(2016) Deepshika Ramanan et al.   SCIENCE

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Effect of Dietary Fibers on Cecal Microbiota and Intestinal Tumorigenesis in Azoxymethane Treated A/J Min/+ Mice

(2016) Birgitte Moen et al.   PLoS One

Maternal exposure to GOS/inulin mixture prevents food allergies and promotes tolerance in offspring in mice

(2015) G. Bouchaud et al.   ALLERGY

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

(2015) Mario M. Zaiss et al.   IMMUNITY

The impact of dietary fibers on dendritic cell responses in vitro is dependent on the differential effects of the fibers on intestinal epithelial cells

(2015) Miriam Bermudez-Brito et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance

(2015) Ashley Houlden et al.   PLoS One

Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli

(2015) Jacob Bak Holm et al.   PLoS One

DUOX2 and DUOXA2 Form the Predominant Enzyme System Capable of Producing the Reactive Oxygen Species H2O2 in Active Ulcerative Colitis and are Modulated by 5-Aminosalicylic Acid

(2014) Tammie S. MacFie et al.   INFLAMMATORY BOWEL DISEASES

Toll-Like Receptor 2 Activation by β2→1-Fructans Protects Barrier Function of T84 Human Intestinal Epithelial Cells in a Chain Length–Dependent Manner

(2014) Leonie M. Vogt et al.   JOURNAL OF NUTRITION

A role for the pattern recognition receptor Nod2 in promoting recruitment of CD103+ dendritic cells to the colon in response to Trichuris muris infection

(2014) R Bowcutt et al.   Mucosal Immunology

Mechanisms underlying immune effects of dietary oligosaccharides

(2013) Prescilla V Jeurink et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Obesity as a Risk Factor for Clostridium difficile Infection

(2013) J. Bishara et al.   CLINICAL INFECTIOUS DISEASES

Role of “Western Diet” in Inflammatory Autoimmune Diseases

(2013) Arndt Manzel et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms

(2013) Yoshio Osada et al.   EXPERIMENTAL PARASITOLOGY

Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis

(2013) Lionel Rigottier-Gois   ISME Journal

Immune Modulation by Different Types of β2→1-Fructans Is Toll-Like Receptor Dependent

(2013) Leonie Vogt et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevention of type 1 diabetes through infection with an intestinal nematode parasite requires IL-10 in the absence of a Th2-type response

(2012) P K Mishra et al.   Mucosal Immunology

The Goblet Cell Is the Cellular Source of the Anti-Microbial Angiogenin 4 in the Large Intestine Post Trichuris muris Infection

(2012) Ruth A. Forman et al.   PLoS One

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines

(2012) M. R. Hepworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trichuris muris: a model of gastrointestinal parasite infection

(2012) Joanna E. Klementowicz et al.   Seminars in Immunopathology

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Regulation of colonic epithelial cell turnover by IDO contributes to the innate susceptibility of SCID mice to Trichuris muris infection

(2010) L. V. BELL et al.   PARASITE IMMUNOLOGY

Role of intestinal Bifidobacterium pseudolongum in dietary fructo-oligosaccharide inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice

(2009) Naho Sasajima et al.   BRITISH JOURNAL OF NUTRITION

Consumption of fructo-oligosaccharide reduces 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice

(2008) Jun Watanabe et al.   BRITISH JOURNAL OF NUTRITION