Specific inulin-type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function, and microbiota homeostasis

Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice

(2016) Isabelle Serr et al.   Nature Communications

Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production

(2016) David Endesfelder et al.   Microbiome

Clostridium Butyricum CGMCC0313.1 Modulates Lipid Profile, Insulin Resistance and Colon Homeostasis in Obese Mice

(2016) Haixiao Shang et al.   PLoS One

A model for the role of gut bacteria in the development of autoimmunity for type 1 diabetes

(2015) Austin G. Davis-Richardson et al.   DIABETOLOGIA

Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota

(2015) Jia Sun et al.   IMMUNITY

The impact of dietary fibers on dendritic cell responses in vitro is dependent on the differential effects of the fibers on intestinal epithelial cells

(2015) Miriam Bermudez-Brito et al.   MOLECULAR NUTRITION & FOOD RESEARCH

NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets

(2015) Changyun Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diet, Microbiota and Immune System in Type 1 Diabetes Development and Evolution

(2015) María Mejía-León et al.   Nutrients

The intestinal microbiome in type 1 diabetes

(2014) J. L. Dunne et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Fermentable fibres condition colon microbiota and promote diabetogenesis in NOD mice

(2014) Raine K. Toivonen et al.   DIABETOLOGIA

Toll-Like Receptor 2 Activation by β2→1-Fructans Protects Barrier Function of T84 Human Intestinal Epithelial Cells in a Chain Length–Dependent Manner

(2014) Leonie M. Vogt et al.   JOURNAL OF NUTRITION

Erratum: Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2014) Yukihiro Furusawa et al.   NATURE

Immunological Properties of Inulin-Type Fructans

(2013) Leonie Vogt et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Promotion of Autoimmune Diabetes by Cereal Diet in the Presence or Absence of Microbes Associated With Gut Immune Activation, Regulatory Imbalance, and Altered Cathelicidin Antimicrobial Peptide

(2013) C. Patrick et al.   DIABETES

Induction of Diabetes in the RIP-B7.1 Mouse Model Is Critically Dependent on TLR3 and MyD88 Pathways and Is Associated With Alterations in the Intestinal Microbiome

(2013) A. K. Alkanani et al.   DIABETES

Casein hydrolysate diet controls intestinal T cell activation, free radical production and microbial colonisation in NOD mice

(2013) R. Emani et al.   DIABETOLOGIA

Immune Modulation by Different Types of β2→1-Fructans Is Toll-Like Receptor Dependent

(2013) Leonie Vogt et al.   PLoS One

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Intraepithelial lymphocytes in celiac disease immunopathology

(2012) Valérie Abadie et al.   Seminars in Immunopathology

Probiotic Bacteria Induce Maturation of Intestinal Claudin 3 Expression and Barrier Function

(2011) Ravi M. Patel et al.   AMERICAN JOURNAL OF PATHOLOGY

Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes

(2011) Alessandra Ferraro et al.   DIABETES

Degree of Polymerization of Inulin-Type Fructans Differentially Affects Number of Lactic Acid Bacteria, Intestinal Immune Functions, and Immunoglobulin A Secretion in the Rat Cecum

(2011) Hiroyuki Ito et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components

(2011) Dulantha Ulluwishewa et al.   JOURNAL OF NUTRITION

Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa

(2011) Peter A. Bron et al.   NATURE REVIEWS MICROBIOLOGY

The Incidence of Type-1 Diabetes in NOD Mice Is Modulated by Restricted Flora Not Germ-Free Conditions

(2011) Cecile King et al.   PLoS One

The gut as a regulator of early inflammation in type 1 diabetes

(2011) Outi Vaarala   Current Opinion in Endocrinology Diabetes and Obesity

Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

(2010) Jurgen Karczewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Prebiotic effects: metabolic and health benefits

(2010) Marcel Roberfroid et al.   BRITISH JOURNAL OF NUTRITION

Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat

(2010) J. T. J. Visser et al.   DIABETOLOGIA

Genetics and Environmental Interactions Shape the Intestinal Microbiome to Promote Inflammatory Bowel Disease Versus Mucosal Homeostasis

(2010) R. Balfour Sartor   GASTROENTEROLOGY

Toward defining the autoimmune microbiome for type 1 diabetes

(2010) Adriana Giongo et al.   ISME Journal

Lactobacillus johnsonii N6.2 Mitigates the Development of Type 1 Diabetes in BB-DP Rats

(2010) Ricardo Valladares et al.   PLoS One

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

(2010) L. Peyrin-Biroulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Th17 Cells Regulates Autoimmune Diabetes in NOD Mice

(2009) J. A. Emamaullee et al.   DIABETES

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

The "Perfect Storm" for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity

(2008) O. Vaarala et al.   DIABETES