Piperlongumine induces apoptotic and autophagic death of the primary myeloid leukemia cells from patients via activation of ROS-p38/JNK pathways

Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition

(2014) Wen-wen Lv et al.   ACTA PHARMACOLOGICA SINICA

Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells

(2014) Shweta Shrivastava et al.   APOPTOSIS

Outcome of patients with abnl(17p) acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation

(2014) J. M. Middeke et al.   BLOOD

Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities

(2014) Yuanyuan Liu et al.   Nanoscale

Piperlongumine induces inhibition of the ubiquitin–proteasome system in cancer cells

(2013) Malin Jarvius et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Piperlongumine selectively kills glioblastoma multiforme cells via reactive oxygen species accumulation dependent JNK and p38 activation

(2013) Ju Mei Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ROS inhibitorN-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors

(2013) Marianna Halasi et al.   BIOCHEMICAL JOURNAL

Neuroglobin Promotes Neurite Outgrowth via Differential Binding to PTEN and Akt

(2013) Li Li et al.   MOLECULAR NEUROBIOLOGY

Piperlongumine inhibits NF-κB activity and attenuates aggressive growth characteristics of prostate cancer cells

(2013) Serge Ginzburg et al.   PROSTATE

Activation of ERK signaling and induction of colon cancer cell death by piperlongumine

(2013) H. Randhawa et al.   TOXICOLOGY IN VITRO

Piperlongumine induces autophagy by targeting p38 signaling

(2013) Y Wang et al.   Cell Death & Disease

The natural compounds piperovatine and piperlonguminine induce autophagic cell death on Trypanosoma cruzi

(2012) Phercyles Veiga-Santos et al.   ACTA TROPICA

Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells

(2012) Konstantin V. Golovine et al.   PROSTATE

Acute leukemia incidence and patient survival among children and adults in the United States, 2001-2007

(2011) G. M. Dores et al.   BLOOD

Autophagy as a therapeutic target in cancer

(2011) Ning Chen et al.   CANCER BIOLOGY & THERAPY

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

(2011) Lakshmi Raj et al.   NATURE

Cytarabine Dose for Acute Myeloid Leukemia

(2011) Bob Löwenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes

(2010) Utz Krug et al.   LANCET

Reactive Oxygen Species-Dependent Apoptosis by Gugulipid Extract of Ayurvedic Medicine Plant Commiphora mukul in Human Prostate Cancer Cells Is Regulated by c-Jun N-Terminal Kinase

(2010) D. Xiao et al.   MOLECULAR PHARMACOLOGY

In vivogrowth inhibition of sarcoma 180 by piperlonguminine, an alkaloid amide from thePiperspecies

(2007) Daniel P. Bezerra et al.   JOURNAL OF APPLIED TOXICOLOGY