Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid

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(2019) Stuart Berg et al.   NATURE METHODS

Mapping the Mouse Cell Atlas by Microwell-Seq

(2018) Xiaoping Han et al.   CELL

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors

(2017) Ignacio Benedicto et al.   Nature Communications

Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium

(2017) Allison E. Songstad et al.   Stem Cells Translational Medicine

Increased choroidal mast cells and their degranulation in age-related macular degeneration

(2016) Imran A Bhutto et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

Expression profiling of constitutive mast cells reveals a unique identity within the immune system

(2016) Daniel F Dwyer et al.   NATURE IMMUNOLOGY

Control of inflammation by stromal Hedgehog pathway activation restrains colitis

(2016) John J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration

(2016) Johanna M. Seddon et al.   JAMA Ophthalmology

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Stem cell based therapies for age-related macular degeneration: The promises and the challenges

(2015) Hossein Nazari et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy

(2015) S. Scott Whitmore et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Sodium iodate induced retinal degeneration: new insights from an old model

(2015) DavidR Hinton et al.   Neural Regeneration Research

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

(2014) Hu Zhao et al.   Cell Stem Cell

Roles for Hedgehog signaling in adult organ homeostasis and repair

(2014) R. Petrova et al.   DEVELOPMENT

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

(2014) Wan Ling Wong et al.   Lancet Global Health

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Mast cells are present in the choroid of the normal eye in most vertebrate classes

(2013) Paul Gerard McMenamin et al.   VETERINARY OPHTHALMOLOGY

Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments

(2012) Andrew McDavid et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The Diaphragms of Fenestrated Endothelia: Gatekeepers of Vascular Permeability and Blood Composition

(2012) Radu V. Stan et al.   DEVELOPMENTAL CELL

Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex

(2012) Imran Bhutto et al.   MOLECULAR ASPECTS OF MEDICINE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Mechanisms of Age-Related Macular Degeneration

(2012) Jayakrishna Ambati et al.   NEURON

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks

(2012) Aaron M Newman et al.   Genome Medicine

Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells

(2011) Isaac Brownell et al.   Cell Stem Cell

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors

(2010) A. Merchant et al.   BLOOD

Development of the human choriocapillaris

(2010) G A Lutty et al.   EYE

Loss of Indian Hedgehog Activates Multiple Aspects of a Wound Healing Response in the Mouse Intestine

(2010) Willemijn A. van Dop et al.   GASTROENTEROLOGY

Hedgehog Is an Anti-Inflammatory Epithelial Signal for the Intestinal Lamina Propria

(2010) William J. Zacharias et al.   GASTROENTEROLOGY

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

The RBL-2H3 cell line: its provenance and suitability as a model for the mast cell

(2009) Egle Passante et al.   INFLAMMATION RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

The multifunctional choroid

(2009) Debora L. Nickla et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye

(2008) Gabriel D. Dakubo et al.   DEVELOPMENTAL BIOLOGY

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY

Mast cell renin and a local renin-angiotensin system in the airway: Role in bronchoconstriction

(2008) A. Veerappan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Germline GLI1 Variation Implicates Hedgehog Signalling in the Regulation of Intestinal Inflammatory Pathways

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