A critical role for plasminogen in inflammation

Origin and diversification of the plasminogen activation system among chordates

(2019) Andrés Chana-Muñoz et al.   BMC EVOLUTIONARY BIOLOGY

Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

(2019) Lakmali Munasinghage Silva et al.   BLOOD

Plasminogen and the Plasminogen Receptor, Plg-RKT, Regulate Macrophage Phenotypic, and Functional Changes

(2019) Juliana P. Vago et al.   Frontiers in Immunology

Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide

(2019) Sarah K. Baker et al.   Journal of Neuroinflammation

Fibrinogen and Altered Hemostasis in Alzheimer's Disease

(2018) Marta Cortes-Canteli et al.   JOURNAL OF ALZHEIMERS DISEASE

Numerous Fasciola plasminogen-binding proteins may underlie blood-brain barrier leakage and explain neurological disorder complexity and heterogeneity in the acute and chronic phases of human fascioliasis

(2018) J. González-Miguel et al.   PARASITOLOGY

Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer’s disease

(2018) Sarah K. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

(2017) Maureen A. Shaw et al.   JOURNAL OF NEUROSCIENCE

Biophysical Mechanisms Mediating Fibrin Fiber Lysis

(2017) Nathan E. Hudson   Biomed Research International

Monocyte Conversion During Inflammation and InjuryHighlights

(2016) Rachel M. Kratofil et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The plasminogen activation system in neuroinflammation

(2016) Anupriya Mehra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Deficiency of plasminogen receptor, Plg-RKT, causes defects in plasminogen binding and inflammatory macrophage recruitmentin vivo

(2016) L. A. Miles et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Plasminogen-receptorKT: plasminogen activation and beyond

(2016) M. J. Flick et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Influence of Differentially Expressed Tissue-Type Plasminogen Activator in Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis

(2016) Lisa CM Dahl et al.   PLoS One

Soluble urokinase plasminogen activator receptor and incidence of venous thromboembolism

(2016) Bengt Zöller et al.   THROMBOSIS AND HAEMOSTASIS

Plasminogen is a critical regulator of cutaneous wound healing

(2016) R. Sulniute et al.   THROMBOSIS AND HAEMOSTASIS

Resolution of Inflammation: What Controls Its Onset?

(2016) Michelle A. Sugimoto et al.   Frontiers in Immunology

Moraxella catarrhalis Binds Plasminogen To Evade Host Innate Immunity

(2015) Birendra Singh et al.   INFECTION AND IMMUNITY

A Novel Interaction between Complement Inhibitor C4b-binding Protein and Plasminogen That Enhances Plasminogen Activation

(2015) Vaibhav Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish between atherothrombotic and non-atherothrombotic myocardial infarction

(2015) Andrew P. DeFilippis et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Minor Role of Plasminogen in Complement Activation on Cell Surfaces

(2015) Satu Hyvärinen et al.   PLoS One

Lp(a)/apo(a) Modulate MMP-9 Activation and Neutrophil Cytokines in Vivo in Inflammation to Regulate Leukocyte Recruitment

(2014) Menggui Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

Plasminogen activation by staphylokinase enhances local spreading of S. aureus in skin infections

(2014) Marijke Peetermans et al.   BMC MICROBIOLOGY

Enolase-like protein present on the outer membrane of Pseudomonas aeruginosa binds plasminogen

(2014) Ireneusz Ceremuga et al.   FOLIA MICROBIOLOGICA

Recombinant Tissue Plasminogen Activator Enhances Microglial Cell Recruitment after Stroke in Mice

(2014) Sébastien Lenglet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Plasminogen in cerebrospinal fluid originates from circulating blood

(2014) Anna Mezzapesa et al.   Journal of Neuroinflammation

Plasmin deficiency leads to fibrin accumulation and a compromised inflammatory response in the mouse brain

(2014) K. Hultman et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Plasminogen Is a Joint-Specific Positive or Negative Determinant of Arthritis Pathogenesis in Mice

(2014) Harini Raghu et al.   Arthritis & Rheumatology

Macrophage Gene Expression and Foam Cell Formation Are Regulated by Plasminogen

(2013) Riku Das et al.   CIRCULATION

Streptococcus pneumoniaeEndopeptidase O (PepO) Is a Multifunctional Plasminogen- and Fibronectin-binding Protein, Facilitating Evasion of Innate Immunity and Invasion of Host Cells

(2013) Vaibhav Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive Genetic Analysis of Complement and Coagulation Genes in Atypical Hemolytic Uremic Syndrome

(2013) F. Bu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteolytic Degradation of Amyloid  -Protein

(2013) T. Saido et al.   Cold Spring Harbor Perspectives in Medicine

A Key Role for the Urokinase Plasminogen Activator (uPA) in Invasive Group A Streptococcal Infection

(2013) Martina L. Sanderson-Smith et al.   PLoS Pathogens

Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis

(2013) Fatma Berri et al.   PLoS Pathogens

A Plasminogen Activator Inhibitor-1 Inhibitor Reduces Airway Remodeling in a Murine Model of Chronic Asthma

(2012) Sun H. Lee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds

(2012) Y. Shen et al.   BLOOD

Plasminogen Is a Complement Inhibitor

(2012) Diana Barthel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Plasminogen Receptors Utilize Host Plasminogen System for Effective Invasion and Dissemination

(2012) Sarbani Bhattacharya et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Oxidized Phospholipids Are Present on Plasminogen, Affect Fibrinolysis, and Increase Following Acute Myocardial Infarction

(2012) Gregor Leibundgut et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Induction of Brain Microvascular Endothelial Cell Urokinase Expression by Cryptococcus neoformans Facilitates Blood-Brain Barrier Invasion

(2012) Jamal Stie et al.   PLoS One

Requirement of Plasminogen Binding to Its Cell-Surface Receptor α-Enolase for Efficient Regeneration of Normal and Dystrophic Skeletal Muscle

(2012) Àngels Díaz-Ramos et al.   PLoS One

Association of elevated plasminogen activator inhibitor 1 levels with diminished lung function in patients with asthma

(2011) Seong Cho et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Activators and inhibitors of the plasminogen system in Alzheimer’s disease

(2011) Rachel Barker et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Blood-brain barrier invasion by Cryptococcus neoformans is enhanced by functional interactions with plasmin

(2011) J. Stie et al.   MICROBIOLOGY-SGM

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(2011) Carla Jennewein et al.   MOLECULAR MEDICINE

Plasmin Plays an Essential Role in Amplification of Psoriasiform Skin Inflammation in Mice

(2011) Qun Li et al.   PLoS One

Beneficial and Detrimental Effects of Plasmin(ogen) during Infection and Sepsis in Mice

(2011) Yongzhi Guo et al.   PLoS One

Fibrinogen as a key regulator of inflammation in disease

(2011) Dimitrios Davalos et al.   Seminars in Immunopathology

Plasminogen and Its Receptors as Regulators of Cardiovascular Inflammatory Responses

(2011) Riku Das et al.   TRENDS IN CARDIOVASCULAR MEDICINE

S100A10 regulates plasminogen-dependent macrophage invasion

(2010) P. A. O'Connell et al.   BLOOD

Plasminogen deficiency

(2010) R. MEHTA et al.   HAEMOPHILIA

Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease

(2010) Marta Cortes-Canteli et al.   NEURON

Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement

(2010) Andrew D Cook et al.   ARTHRITIS RESEARCH & THERAPY

Urokinase-type plasminogen activator and arthritis progression: contrasting roles in systemic and monoarticular arthritis models

(2010) Christine M De Nardo et al.   ARTHRITIS RESEARCH & THERAPY

Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation

(2009) N. M. Andronicos et al.   BLOOD

L-Type Calcium Channel Blockers Exert an Antiinflammatory Effect by Suppressing Expression of Plasminogen Receptors on Macrophages

(2009) Riku Das et al.   CIRCULATION RESEARCH

Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study

(2009) A. P. REINER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice

(2008) Yanqing Gong et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic

(2008) Manuel Yepes et al.   TRENDS IN NEUROSCIENCES

Plasminogen Alleles Influence Susceptibility to Invasive Aspergillosis

(2008) Aimee K. Zaas et al.   PLoS Genetics