Biophysical Mechanisms Mediating Fibrin Fiber Lysis

Fibrin Fiber Stiffness Is Strongly Affected by Fiber Diameter, but Not by Fibrinogen Glycation

(2016) Wei Li et al.   BIOPHYSICAL JOURNAL

Ranking reactive glutamines in the fibrinogen  C region that are targeted by blood coagulant factor XIII

(2016) K. N. Mouapi et al.   BLOOD

Compaction of fibrin clots reveals the antifibrinolytic effect of factor XIII

(2016) D. C. Rijken et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Assessing Safety of Thrombolytic Therapy

(2016) Johannes Sidelmann et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Coagulation factor XIIIa is inactivated by plasmin

(2015) W. S. Hur et al.   BLOOD

Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin  -chain crosslinking

(2015) J. R. Byrnes et al.   BLOOD

Towards a multi-physics modelling framework for thrombolysis under the influence of blood flow

(2015) Andris Piebalgs et al.   Journal of the Royal Society Interface

Basic mechanisms and regulation of fibrinolysis

(2015) C. Longstaff et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Physical Determinants of Fibrinolysis in Single Fibrin Fibers

(2015) Igal Bucay et al.   PLoS One

Fractal Kinetic Behavior of Plasmin on the Surface of Fibrin Meshwork

(2014) Imre Varjú et al.   BIOCHEMISTRY

Factor XIII activity mediates red blood cell retention in venous thrombi

(2014) Maria M. Aleman et al.   JOURNAL OF CLINICAL INVESTIGATION

Factor XIII stiffens fibrin clots by causing fiber compaction

(2014) N. A. Kurniawan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Roles of fibrin α- and γ-chain specific cross-linking by FXIIIa in fibrin structure and function

(2014) Cédric Duval et al.   THROMBOSIS AND HAEMOSTASIS

Platelet-related fibrinolysis resistance in patients suffering from PV. Impact of clot retraction and isovolemic erythrocytapheresis

(2014) Tomasz Rusak et al.   THROMBOSIS RESEARCH

Submillisecond Elastic Recoil Reveals Molecular Origins of Fibrin Fiber Mechanics

(2013) Nathan E. Hudson et al.   BIOPHYSICAL JOURNAL

The Hydraulic Permeability of Blood Clots as a Function of Fibrin and Platelet Density

(2013) A.R. Wufsus et al.   BIOPHYSICAL JOURNAL

Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin

(2013) D. B. Cines et al.   BLOOD

The effect of blood coagulation factor XIII on fibrin clot structure and fibrinolysis

(2013) E. L. Hethershaw et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

On the Mechanism of αC Polymer Formation in Fibrin

(2012) Galina Tsurupa et al.   BIOCHEMISTRY

A Modular Fibrinogen Model that Captures the Stress-Strain Behavior of Fibrin Fibers

(2012) Rodney D. Averett et al.   BIOPHYSICAL JOURNAL

α−α Cross-Links Increase Fibrin Fiber Elasticity and Stiffness

(2012) Christine C. Helms et al.   BIOPHYSICAL JOURNAL

So Many Plasminogen Receptors: Why?

(2012) Edward F. Plow et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Mechanical Transition from α-Helical Coiled Coils to β-Sheets in Fibrin(ogen)

(2012) Artem Zhmurov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of the native plasminogen reveals an activation-resistant compact conformation

(2012) Y. XUE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Regulation of fibrinolysis by C-terminal lysines operates through plasminogen and plasmin but not tissue-type plasminogen activator

(2012) M. M. C. G. SILVA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Modelling fibrinolysis: a 3D stochastic multiscale model

(2012) B. E. Bannish et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

The X-ray Crystal Structure of Full-Length Human Plasminogen

(2012) Ruby H.P. Law et al.   Cell Reports

Lytic Resistance of Fibrin Containing Red Blood Cells

(2011) Nikolett Wohner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Strain Tunes Proteolytic Degradation and Diffusive Transport in Fibrin Networks

(2011) Arjun S. Adhikari et al.   BIOMACROMOLECULES

Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

(2011) K. R. Machlus et al.   BLOOD

The antifibrinolytic function of factor XIII is exclusively expressed through  2-antiplasmin cross-linking

(2011) S. R. Fraser et al.   BLOOD

Interactions between factor XIII and the  C region of fibrinogen

(2011) K. A. Smith et al.   BLOOD

Identification of Respective Lysine Donor and Glutamine Acceptor Sites Involved in Factor XIIIa-catalyzed Fibrin α Chain Cross-linking

(2011) Weixun Wang   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue-type plasminogen activator-mediated plasminogen activation and contact activation, implications in and beyond haemostasis

(2011) M. F. B. G. GEBBINK   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hindered dissolution of fibrin formed under mechanical stress

(2011) I. VARJÚ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Noncovalent Interaction of α2-Antiplasmin with Fibrin(ogen): Localization of α2-Antiplasmin-Binding Sites

(2010) Galina Tsurupa et al.   BIOCHEMISTRY

The molecular origins of the mechanical properties of fibrin

(2010) Michael R. Falvo et al.   BIOPHYSICAL CHEMISTRY

Evidence that αC Region Is Origin of Low Modulus, High Extensibility, and Strain Stiffening in Fibrin Fibers

(2010) John R. Houser et al.   BIOPHYSICAL JOURNAL

Nanostructure of the Fibrin Clot

(2010) C. Yeromonahos et al.   BIOPHYSICAL JOURNAL

Structural Hierarchy Governs Fibrin Gel Mechanics

(2010) Izabela K. Piechocka et al.   BIOPHYSICAL JOURNAL

The interplay between tissue plasminogen activator domains and fibrin structures in the regulation of fibrinolysis: kinetic and microscopic studies

(2010) C. Longstaff et al.   BLOOD

The plasmin–antiplasmin system: structural and functional aspects

(2010) Johann Schaller et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Plasma and cellular contributions to fibrin network formation, structure and stability

(2010) A. S. WOLBERG   HAEMOPHILIA

Activation of single-chain urokinase-type plasminogen activator by platelet-associated plasminogen: a mechanism for stimulation of fibrinolysis by platelets

(2010) K. M. BAETEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Flow rate and fibrin fiber alignment

(2010) K. C. GERSH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The mechanical properties of single fibrin fibers

(2010) W. Liu et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanics and contraction dynamics of single platelets and implications for clot stiffening

(2010) Wilbur A. Lam et al.   NATURE MATERIALS

Flow profoundly influences fibrin network structure: Implications for fibrin formation and clot stability in haemostasis

(2010) Robert A. Campbell et al.   THROMBOSIS AND HAEMOSTASIS

Microscopic clot fragment evidence of biochemo-mechanical degradation effects in thrombolysis

(2010) Franci Bajd et al.   THROMBOSIS RESEARCH

Structure, Stability, and Interaction of the Fibrin(ogen) αC-Domains

(2009) Galina Tsurupa et al.   BIOCHEMISTRY

Crystal Structure of Human Fibrinogen

(2009) Justin M. Kollman et al.   BIOCHEMISTRY

Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stability

(2009) R. A. Campbell et al.   BLOOD

Structure, function and antagonists of urokinase-type plasminogen activator

(2009) Maria Vincenza Carriero   Frontiers in Bioscience-Landmark

Molecular mechanisms of the polymerization of fibrin and the formation of its three-dimensional network

(2009) E. V. Lugovskoi et al.   RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

Multiscale Mechanics of Fibrin Polymer: Gel Stretching with Protein Unfolding and Loss of Water

(2009) A. E. X. Brown et al.   SCIENCE

Cellular Procoagulant Activity Dictates Clot Structure and Stability as a Function of Distance From the Cell Surface

(2008) Robert A. Campbell et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fibrin architecture in clots: A quantitative polarized light microscopy analysis☆

(2008) P WHITTAKER et al.   BLOOD CELLS MOLECULES AND DISEASES

Length of tandem repeats in fibrin’s αC region correlates with fiber extensibility

(2008) M. R. FALVO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Recommendations for nomenclature on fibrinogen and fibrin

(2008) L. MEDVED et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Complexity of “A−a” Knob−Hole Fibrin Interaction Revealed by Atomic Force Spectroscopy

(2008) Laurel E. Averett et al.   LANGMUIR

Ultrathin self-assembled fibrin sheets

(2008) E. T. O'Brien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of Fibrin Clot Elasticity

(2008) Bernard B.C. Lim et al.   STRUCTURE