Screening of a virtual mirror-image library of natural products

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Convergent Versus Sequential Protein Synthesis: The Case of Ubiquitinated and Glycosylated H2B

(2015) Mallikanti Seenaiah et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of a Natural-Product-Derived Chemical Toolbox for Modulation of Protein Function

(2014) Stefano Rizzo et al.   CHEMICAL REVIEWS

Co-Cultivation—A Powerful Emerging Tool for Enhancing the Chemical Diversity of Microorganisms

(2014) Andreas Marmann et al.   Marine Drugs

Natural product and natural product derived drugs in clinical trials

(2014) Mark S. Butler et al.   NATURAL PRODUCT REPORTS

Development of Diversity-Enhanced Extracts of Curcuma zedoaria and Their New Sesquiterpene-like Compounds

(2014) Haruhisa Kikuchi et al.   ORGANIC LETTERS

Synthesis and folding of a mirror-image enzyme reveals ambidextrous chaperone activity

(2014) M. T. Weinstock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Affinity-based screening of MDM2/MDMX–p53 interaction inhibitors by chemical array: Identification of novel peptidic inhibitors

(2013) Taro Noguchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products

(2013) Robert W. Huigens III et al.   Nature Chemistry

Classical and epigenetic approaches to metabolite diversification in filamentous fungi

(2013) Jacqueline Aparecida Takahashi et al.   PHYTOCHEMISTRY REVIEWS

Erythropoietin Derived by Chemical Synthesis

(2013) P. Wang et al.   SCIENCE

Enantiomeric Natural Products: Occurrence and Biogenesis

(2012) Jennifer M. Finefield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Left-Handed Solution to Peptide Inhibition of the p53-MDM2 Interaction

(2010) Min Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx

(2010) Anna Czarna et al.   CELL CYCLE

D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms

(2010) M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of Natural Product Inspired Compound Collections

(2009) Kamal Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

Reduction of Alzheimer’s Disease Amyloid Plaque Load in Transgenic Mice by D3, a D-Enantiomeric Peptide Identified by Mirror Image Phage Display

(2008) Thomas van Groen et al.   ChemMedChem

d-Amino acids in the brain: d-serine in neurotransmission and neurodegeneration

(2008) Herman Wolosker et al.   FEBS Journal

Mirror Image Forms of Snow Flea Antifreeze Protein Prepared by Total Chemical Synthesis Have Identical Antifreeze Activities

(2008) Brad L. Pentelute et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray Structure of Snow Flea Antifreeze Protein Determined by Racemic Crystallization of Synthetic Protein Enantiomers

(2008) Brad L. Pentelute et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Epigenetic remodeling of the fungal secondary metabolome

(2008) Russell B. Williams et al.   ORGANIC & BIOMOLECULAR CHEMISTRY