DNA hypermethylation during tuberculosis dampens host immune responsiveness

FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing

(2019) Mathieu Ringeard et al.   NATURE

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

(2019) Brian C. Miller et al.   NATURE IMMUNOLOGY

Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes

(2018) Andrew R. DiNardo et al.   JOURNAL OF IMMUNOLOGY

PD-1 Expression on Mycobacterium tuberculosis-Specific CD4 T Cells Is Associated With Bacterial Load in Human Tuberculosis

(2018) Cheryl L. Day et al.   Frontiers in Immunology

IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade

(2017) Mark Ayers et al.   JOURNAL OF CLINICAL INVESTIGATION

Human papillomaviruses in epigenetic regulations

(2017) Julia Durzynska et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Exhaustion-associated regulatory regions in CD8+tumor-infiltrating T cells

(2017) Giuliana P. Mognol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis

(2016) Andrea Schietinger et al.   IMMUNITY

Demethylation of the PD-1 Promoter Is Imprinted during the Effector Phase of CD8 T Cell Exhaustion

(2016) Eunseon Ahn et al.   JOURNAL OF VIROLOGY

Treatment Outcomes in Multidrug-Resistant Tuberculosis

(2016) Gunar Günther et al.   NEW ENGLAND JOURNAL OF MEDICINE

The epigenetic landscape of T cell exhaustion

(2016) D. R. Sen et al.   SCIENCE

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

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Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types

(2016) Vitor Onuchic et al.   Cell Reports

Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection

(2016) Garima Sharma et al.   Scientific Reports

SnapShot: T Cell Exhaustion

(2015) Kristen E. Pauken et al.   CELL

The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells

(2015) Gustavo J. Martinez et al.   IMMUNITY

The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG methylation and histone H3/H4 binding

(2015) Garima Sharma et al.   NUCLEIC ACIDS RESEARCH

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(2015) Shannon M. Kahan et al.   VIROLOGY

Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3

(2015) Imtiyaz Yaseen et al.   Nature Communications

Mycobacterium tuberculosis Infection Induces HDAC1-Mediated Suppression of IL-12B Gene Expression in Macrophages

(2015) Aneesh Chandran et al.   Frontiers in Cellular and Infection Microbiology

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Systematic review and meta-analysis on the utility of Interferon-gamma release assays for the diagnosis of Mycobacterium tuberculosis infection in children: a 2013 update

(2014) S Sollai et al.   BMC INFECTIOUS DISEASES

Whole genome DNA methylation signature of HER2-positive breast cancer

(2014) Breezy M Lindqvist et al.   Epigenetics

Epigenetic Repression of Interleukin 2 Expression in Senescent CD4+T Cells During Chronic HIV Type 1 Infection

(2014) Kaori Nakayama-Hosoya et al.   JOURNAL OF INFECTIOUS DISEASES

Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis

(2014) Stephen H. Gillespie et al.   NEW ENGLAND JOURNAL OF MEDICINE

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Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity

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Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages

(2014) Alexandra K. Marr et al.   PLoS Pathogens

Transcription factor interplay in T helper cell differentiation

(2013) C. M. Evans et al.   Briefings in Functional Genomics

Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells

(2013) B. Youngblood et al.   JOURNAL OF IMMUNOLOGY

Inhibiting the Programmed Death 1 Pathway Rescues Mycobacterium tuberculosis–Specific Interferon γ–Producing T Cells From Apoptosis in Patients With Pulmonary Tuberculosis

(2013) Amar Singh et al.   JOURNAL OF INFECTIOUS DISEASES

Tuberculosis Recurrence after Completion Treatment in a European City: Reinfection or Relapse?

(2013) Juan-Pablo Millet et al.   PLoS One

Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory

(2012) Travis A. Doering et al.   IMMUNITY

Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection

(2012) A. M. Mandalakas et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

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Interferon-γ Release Assays for Active Pulmonary Tuberculosis Diagnosis in Adults in Low- and Middle-Income Countries: Systematic Review and Meta-analysis

(2011) John Z. Metcalfe et al.   JOURNAL OF INFECTIOUS DISEASES

Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease

(2011) Alexandre Harari et al.   NATURE MEDICINE

Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood Cells

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