The proinflammatory cytokines IL‐1β and TNF‐α modulate corneal epithelial wound healing through p16 Ink4a suppressing STAT3 activity

Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants

(2019) Holly Bachus et al.   IMMUNITY

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

(2019) Georgios Kalamakis et al.   CELL

Targeting Interleukin-6 Signaling in Clinic

(2019) Sujin Kang et al.   IMMUNITY

TNF and IL-1 Play Essential but Temporally Distinct Roles in Driving Cardiac Inflammation in a Murine Model of Kawasaki Disease

(2019) Angus T. Stock et al.   JOURNAL OF IMMUNOLOGY

TIPE2 suppresses Pseudomonas aeruginosa keratitis by inhibiting NF-κB signaling and the infiltration of inflammatory cells

(2019) Qun Wang et al.   JOURNAL OF INFECTIOUS DISEASES

Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING

(2019) Lauren D. Aarreberg et al.   MOLECULAR CELL

The impact of hyperglycemia on the corneal epithelium: Molecular mechanisms and insight

(2019) Luke Zhu et al.   Ocular Surface

Corneal Repair and Regeneration: Current Concepts and Future Directions

(2019) Mohammadmahdi Mobaraki et al.   Frontiers in Bioengineering and Biotechnology

Pivotal Role of STAT3 in Shaping Glioblastoma Immune Microenvironment

(2019) Christina Piperi et al.   Cells

Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice

(2018) Delphine Gomez et al.   NATURE MEDICINE

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

GRIM‐19 repressed hypoxia‐induced invasion and EMT of colorectal cancer by repressing autophagy through inactivation of STAT3/HIF‐1α signaling axis

(2018) Juan Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Different Effects of Pro-Inflammatory Factors and Hyperosmotic Stress on Corneal Epithelial Stem/Progenitor Cells and Wound Healing in Mice

(2018) Lingling Yang et al.   Stem Cells Translational Medicine

17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway

(2017) Pei Li et al.   International Journal of Biological Sciences

Diabetic Foot Ulcers and Their Recurrence

(2017) David G. Armstrong et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diabetic complications in the cornea

(2017) Alexander V. Ljubimov   VISION RESEARCH

Targeting Imbalance between IL-1β and IL-1 Receptor Antagonist Ameliorates Delayed Epithelium Wound Healing in Diabetic Mouse Corneas

(2016) Chenxi Yan et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-1β and tumour necrosis factor-α levels in conjunctiva of diabetic patients with symptomatic moderate dry eye: case–control study

(2016) Chen Zhang et al.   BMJ Open

Dry Eye Syndrome in Patients with Diabetes Mellitus: Prevalence, Etiology, and Clinical Characteristics

(2016) Xinyuan Zhang et al.   Journal of Ophthalmology

Senescence Mediated by p16INK4a Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest Progenitors

(2016) Wen-Juan Lu et al.   Scientific Reports

Infection risk associated with anti-TNF-α agents: a review

(2015) Giuseppe Murdaca et al.   Expert Opinion On Drug Safety

Progress in corneal wound healing

(2015) Alexander V. Ljubimov et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Ciliary Neurotrophic Factor Promotes the Activation of Corneal Epithelial Stem/Progenitor Cells and Accelerates Corneal Epithelial Wound Healing

(2015) Qingjun Zhou et al.   STEM CELLS

An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

(2014) Marco Demaria et al.   DEVELOPMENTAL CELL

Substance P Promotes Diabetic Corneal Epithelial Wound Healing Through Molecular Mechanisms Mediated via the Neurokinin-1 Receptor

(2014) L. Yang et al.   DIABETES

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Crosstalk between the Rb Pathway and AKT Signaling Forms a Quiescence-Senescence Switch

(2014) Yoshinori Imai et al.   Cell Reports

Rebamipide increases barrier function and attenuates TNFα-induced barrier disruption and cytokine expression in human corneal epithelial cells

(2013) Hiroshi Tanaka et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis

(2013) Takahiro Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of epithelial STAT3 regulates intestinal homeostasis

(2011) Clemens Neufert et al.   CELL CYCLE

Role of senescent fibroblasts on alkali-induced corneal neovascularization

(2011) Qingjun Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

GRIM-19 and p16INK4aSynergistically Regulate Cell Cycle Progression and E2F1-responsive Gene Expression

(2010) Peng Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

(2010) Maoyin Pang et al.   KIDNEY INTERNATIONAL

High Glucose Suppresses Epidermal Growth Factor Receptor/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and Attenuates Corneal Epithelial Wound Healing

(2009) K.-P. Xu et al.   DIABETES

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stratified epithelial sheets engineered from a single adult murine corneal/limbal progenitor cell

(2008) Tetsuya Kawakita et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

SOCS3 Negatively Regulates the gp130–STAT3 Pathway in Mouse Skin Wound Healing

(2008) Bing-Mei Zhu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE