Seizure‐induced impairment in neuronal ketogenesis: Role of zinc‐α2‐glycoprotein in mitochondria

Concurrent exercise improves insulin resistance and nonalcoholic fatty liver disease by upregulating PPAR-γ and genes involved in the beta-oxidation of fatty acids in ApoE-KO mice fed a high-fat diet

(2019) Fan Zheng et al.   Lipids in Health and Disease

Expression and Function of Zinc-α2-Glycoprotein

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Insulin attenuates epileptiform discharge-induced oxidative stress by increasing zinc-α2-glycoprotein in primary cultured cortical neurons

(2019) Xin Wei et al.   NEUROREPORT

The tumor secretory factor ZAG promotes white adipose tissue browning and energy wasting

(2018) Sawsan Elattar et al.   FASEB JOURNAL

Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats

(2018) Ying Liu et al.   Journal of Neuroinflammation

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

(2018) Katrin Augustin et al.   LANCET NEUROLOGY

High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR-γ

(2018) Kunal Sikder et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Synergistic protection against acute flurothyl-induced seizures by adjuvant treatment of the ketogenic diet with the type 2 diabetes drug pioglitazone

(2017) Timothy A. Simeone et al.   EPILEPSIA

Neuronal inhibition and seizure suppression by acetoacetate and its analog, 2-phenylbutyrate

(2017) Atsushi Kadowaki et al.   EPILEPSIA

Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy

(2017) Timothy A. Simeone et al.   EXPERIMENTAL NEUROLOGY

Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes

(2017) Xinhua Xiao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ketone Bodies as Anti-Seizure Agents

(2017) Timothy A. Simeone et al.   NEUROCHEMICAL RESEARCH

Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats

(2017) Ying Liu et al.   NEUROSCIENCE

A randomized controlled trial of the ketogenic diet in refractory childhood epilepsy

(2016) D. A. J. E. Lambrechts et al.   ACTA NEUROLOGICA SCANDINAVICA

New differentially expressed genes and differential DNA methylation underlying refractory epilepsy

(2016) Xi Liu et al.   Oncotarget

Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor Increases Circulating Zinc-Α2-Glycoprotein Levels in Patients with Type 2 Diabetes

(2016) Xin Liao et al.   Scientific Reports

Targeting LDH enzymes with a stiripentol analog to treat epilepsy

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Roles and Regulation of Ketogenesis in Cultured Astroglia and Neurons Under Hypoxia and Hypoglycemia

(2014) Shinichi Takahashi et al.   ASN Neuro

The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages

(2014) Mahbubur Rahman et al.   Nature Communications

Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity

(2014) Linlin Zhang et al.   Protein & Cell

HSPA8/HSC70 chaperone protein

(2013) François Stricher et al.   Autophagy

The PPARγ agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus

(2013) Sun Hong et al.   NEUROCHEMISTRY INTERNATIONAL

Inhibition of preadipocyte differentiation and adipogenesis by zinc-α2-glycoprotein treatment in 3T3-L1 cells

(2013) Hui-Juan Zhu et al.   Journal of Diabetes Investigation

Impaired fatty acid oxidation in a Drosophila model of mitochondrial trifunctional protein (MTP) deficiency

(2012) Yoshihito Kishita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Downregulation of Fetuin-B and Zinc-a2-glycoprotein is Linked to Impaired Fatty Acid Metabolism in Liver Cells

(2012) Jung-Won Choi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Possible involvement of PPAR-gamma receptor and nitric oxide pathway in the anticonvulsant effect of acute pioglitazone on pentylenetetrazole-induced seizures in mice

(2012) Razieh Adabi Mohazab et al.   EPILEPSY RESEARCH

Comprehensive review on the HSC70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potential

(2012) Tuoen Liu et al.   PHARMACOLOGY & THERAPEUTICS

Ketogenic diet-induced peroxisome proliferator-activated receptor-γ activation decreases neuroinflammation in the mouse hippocampus after kainic acid-induced seizures

(2011) Eun Ae Jeong et al.   EXPERIMENTAL NEUROLOGY

Polyunsaturated fatty acids and epilepsy

(2010) Ameer Y. Taha et al.   EPILEPSIA

Studies on the anti-obesity activity of zinc-α2-glycoprotein in the rat

(2010) S T Russell et al.   INTERNATIONAL JOURNAL OF OBESITY

Metabolic Control of Vesicular Glutamate Transport and Release

(2010) Narinobu Juge et al.   NEURON

Effectiveness of the ketogenic diet in a broad range of seizure types and EEG features for severe childhood epilepsies

(2009) S. Beniczky et al.   ACTA NEUROLOGICA SCANDINAVICA

Diet-induced acidosis: is it real and clinically relevant?

(2009) Joseph Pizzorno et al.   BRITISH JOURNAL OF NUTRITION

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

(2008) Elizabeth G Neal et al.   LANCET NEUROLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols