A flexible network of vimentin intermediate filaments promotes migration of amoeboid cancer cells through confined environments

Mechanisms of 3D cell migration

(2019) Kenneth M. Yamada et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype

(2018) Masaki Makise et al.   BMC CANCER

An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells

(2018) Kathryn P. Trogden et al.   FASEB JOURNAL

c-Src activity is differentially required by cancer cell motility modes

(2018) Jeremy S. Logue et al.   ONCOGENE

Regulation of microtubule-associated motors drives intermediate filament network polarization

(2017) Cécile Leduc et al.   JOURNAL OF CELL BIOLOGY

Vimentin fibers orient traction stress

(2017) Nancy Costigliola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration

(2016) Zhuo Gan et al.   Cell Systems

Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility

(2015) Verena Ruprecht et al.   CELL

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Force transmission during adhesion-independent migration

(2015) Martin Bergert et al.   NATURE CELL BIOLOGY

Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers

(2015) Yaming Jiu et al.   Cell Reports

Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration

(2015) Jeremy S Logue et al.   eLife

Vimentin Enhances Cell Elastic Behavior and Protects against Compressive Stress

(2014) M.G. Mendez et al.   BIOPHYSICAL JOURNAL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Quantitative and unbiased analysis of directional persistence in cell migration

(2014) Roman Gorelik et al.   Nature Protocols

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

(2013) Melda Tozluoğlu et al.   NATURE CELL BIOLOGY

Molecular insight in the multifunctional activities of Withaferin A

(2012) Wim Vanden Berghe et al.   BIOCHEMICAL PHARMACOLOGY

Statin Use and Reduced Cancer-Related Mortality

(2012) Sune F. Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Withaferin A Alters Intermediate Filament Organization, Cell Shape and Behavior

(2012) Boris Grin et al.   PLoS One

Low-Density Lipoprotein Cholesterol and the Risk of Cancer: A Mendelian Randomization Study

(2011) Marianne Benn et al.   JNCI-Journal of the National Cancer Institute

Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

(2010) Melissa G. Mendez et al.   FASEB JOURNAL

A novel function for vimentin: the potential biomarker for predicting melanoma hematogenous metastasis

(2010) Man Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

(2010) K Vuoriluoto et al.   ONCOGENE

Vimentin Regulates Scribble Activity by Protecting It from Proteasomal Degradation

(2009) Dominic C.Y. Phua et al.   MOLECULAR BIOLOGY OF THE CELL