The interferon-inducible protein TDRD7 inhibits AMP-activated protein kinase and thereby restricts autophagy-independent virus replication

Interferon-Independent Upregulation of Interferon-Stimulated Genes during Human Cytomegalovirus Infection is Dependent on IRF3 Expression

(2019) Caroline Ashley et al.   Viruses-Basel

Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy

(2019) Xing Liu et al.   JOURNAL OF VIROLOGY

The ICP0 protein of herpes simplex virus 1 (HSV-1) down-regulates major autophagy adaptor proteins, sequestosome 1 (SQSTM1/p62) and optineurin (OPTN), during the early stages of HSV-1 infection.

(2019) Hope Waisner et al.   JOURNAL OF VIROLOGY

Special Issue "IFN-Independent ISG Expression and its Role in Antiviral Cell-Intrinsic Innate Immunity"

(2019) Thomas et al.   Viruses-Basel

AMPK: Sensing Glucose as well as Cellular Energy Status

(2018) Sheng-Cai Lin et al.   Cell Metabolism

Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis

(2018) Miao Li et al.   JOURNAL OF VIROLOGY

A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

(2018) Gayatri Subramanian et al.   PLoS Pathogens

Intracellular Staphylococcus aureus Modulates Host Central Carbon Metabolism To Activate Autophagy

(2018) Natalia Bravo-Santano et al.   mSphere

AMP-Activated Protein Kinase and Host Defense against Infection

(2018) Prashanta Silwal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress

(2017) Elizabeth I. Vink et al.   JOURNAL OF VIROLOGY

Dengue Virus Activates the AMP Kinase-mTOR Axis To Stimulate a Proviral Lipophagy

(2017) Tristan X. Jordan et al.   JOURNAL OF VIROLOGY

Role of autophagy in Zika virus infection and pathogenesis

(2017) Abhilash I. Chiramel et al.   VIRUS RESEARCH

Autophagy interaction with herpes simplex virus type-1 infection

(2016) Douglas O'Connell et al.   Autophagy

STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection

(2016) Xin Wang et al.   Cell Host & Microbe

AMP-activated Protein Kinase As a Target For Pathogens: Friends Or Foes?

(2016) Diana Moreira et al.   CURRENT DRUG TARGETS

Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

(2016) Saurabh Chattopadhyay et al.   IMMUNITY

AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling

(2016) Daniel Prantner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53 Is a Host Cell Regulator during Herpes Simplex Encephalitis

(2016) Yuhei Maruzuru et al.   JOURNAL OF VIROLOGY

Intrinsic and Innate Defenses of Neurons: Détente with the Herpesviruses

(2016) Lynn W. Enquist et al.   JOURNAL OF VIROLOGY

Dissection and integration of the autophagy signaling network initiated by bluetongue virus infection: crucial candidates ERK1/2, Akt and AMPK

(2016) Shuang Lv et al.   Scientific Reports

The AMPKα1 Pathway Positively Regulates the Developmental Transition from Proliferation to Quiescence in Trypanosoma brucei

(2016) Manuel Saldivia et al.   Cell Reports

The KSHV K1 Protein Modulates AMPK Function to Enhance Cell Survival

(2016) Penny M. Anders et al.   PLoS Pathogens

Early activation of MyD88-mediated autophagy sustains HSV-1 replication in human monocytic THP-1 cells

(2016) Gabriel Siracusano et al.   Scientific Reports

The pros and cons of autophagic flux among herpesviruses

(2015) Charles Grose et al.   Autophagy

Mx GTPases: dynamin-like antiviral machines of innate immunity

(2015) Otto Haller et al.   TRENDS IN MICROBIOLOGY

RIG-I in RNA virus recognition

(2015) Alison M. Kell et al.   VIROLOGY

Dendritic Cell Autophagy Contributes to Herpes Simplex Virus-Driven Stromal Keratitis and Immunopathology

(2015) Yike Jiang et al.   mBio

RIG-I-like receptor regulation in virus infection and immunity

(2015) Ying Kai Chan et al.   Current Opinion in Virology

No Love Lost Between Viruses and Interferons

(2015) Volker Fensterl et al.   Annual Review of Virology

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Tyrosine phosphorylation in Toll-like receptor signaling

(2014) Saurabh Chattopadhyay et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Antiviral RNA recognition and assembly by RLR family innate immune sensors

(2014) Annie M. Bruns et al.   CYTOKINE & GROWTH FACTOR REVIEWS

dsRNA-Activation of TLR3 and RLR Signaling: Gene Induction-Dependent and Independent Effects

(2014) Saurabh Chattopadhyay et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Beta Interferon Regulation of Glucose Metabolism Is PI3K/Akt Dependent and Important for Antiviral Activity against Coxsackievirus B3

(2014) J. D. Burke et al.   JOURNAL OF VIROLOGY

Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis

(2014) Volker Fensterl et al.   JOURNAL OF VIROLOGY

The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling

(2014) Xin Cai et al.   MOLECULAR CELL

Autophagic flux without a block differentiates varicella-zoster virus infection from herpes simplex virus infection

(2014) Erin M. Buckingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirtuins Are Evolutionarily Conserved Viral Restriction Factors

(2014) Emre Koyuncu et al.   mBio

Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling

(2013) Hiroyasu Konno et al.   CELL

STING-dependent cytosolic DNA sensing pathways

(2013) Glen N. Barber   TRENDS IN IMMUNOLOGY

Viperin Regulates Cellular Lipid Metabolism during Human Cytomegalovirus Infection

(2013) Jun-Young Seo et al.   PLoS Pathogens

Feeding Uninvited Guests: mTOR and AMPK Set the Table for Intracellular Pathogens

(2013) Jason Brunton et al.   PLoS Pathogens

IFITM Proteins Restrict Viral Membrane Hemifusion

(2013) Kun Li et al.   PLoS Pathogens

A Neuron-Specific Role for Autophagy in Antiviral Defense against Herpes Simplex Virus

(2012) Brian Yordy et al.   Cell Host & Microbe

Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection

(2012) L. J. Terry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HCMV Targets the Metabolic Stress Response through Activation of AMPK Whose Activity Is Important for Viral Replication

(2012) Jessica McArdle et al.   PLoS Pathogens

AMPK and autophagy get connected

(2011) D Grahame Hardie   EMBO JOURNAL

AMP-activated Protein Kinase Suppresses Matrix Metalloproteinase-9 Expression in Mouse Embryonic Fibroblasts

(2011) Yuki Morizane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early Induction of Autophagy in Human Fibroblasts after Infection with Human Cytomegalovirus or Herpes Simplex Virus 1

(2011) S. McFarlane et al.   JOURNAL OF VIROLOGY

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma

(2011) S. A. Lachke et al.   SCIENCE

Stress Granules in the Viral Replication Cycle

(2011) Hilda Montero et al.   Viruses-Basel

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Viral apoptosis is induced by IRF-3-mediated activation of Bax

(2010) Saurabh Chattopadhyay et al.   EMBO JOURNAL

New Insights into the Role of RNase L in Innate Immunity

(2010) Arindam Chakrabarti et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Human Cytomegalovirus Activates Glucose Transporter 4 Expression To Increase Glucose Uptake during Infection

(2010) Y. Yu et al.   JOURNAL OF VIROLOGY

Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

(2010) J. Mankouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Kinome RNAi Screen Identified AMPK as Promoting Poxvirus Entry through the Control of Actin Dynamics

(2010) Theresa S. Moser et al.   PLoS Pathogens

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic  -helix

(2009) E. R. Hinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE