Efficient SNP editing in haploid human pluripotent stem cells

In vitro expansion of human sperm through nuclear transfer

(2019) Xiaoyu Merlin Zhang et al.   CELL RESEARCH

Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base Editing in Human Cells and Heterozygous Embryos

(2018) Yanting Zeng et al.   MOLECULAR THERAPY

Inter-homologue repair in fertilized human eggs?

(2018) Dieter Egli et al.   NATURE

Large deletions induced by Cas9 cleavage

(2018) Fatwa Adikusuma et al.   NATURE

CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein

(2017) Lichun Tang et al.   MOLECULAR GENETICS AND GENOMICS

Correction of a pathogenic gene mutation in human embryos

(2017) Hong Ma et al.   NATURE

Genome editing reveals a role for OCT4 in human embryogenesis

(2017) Norah M. E. Fogarty et al.   NATURE

Genomic instability during reprogramming by nuclear transfer is DNA replication dependent

(2017) Gloryn Chia et al.   NATURE CELL BIOLOGY

An important intestinal transporter that regulates the enterohepatic circulation of bile acids and cholesterol homeostasis: The apical sodium-dependent bile acid transporter (SLC10A2/ASBT)

(2017) Ling Xiao et al.   Clinics and Research in Hepatology and Gastroenterology

Derivation and differentiation of haploid human embryonic stem cells

(2016) Ido Sagi et al.   NATURE

Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

(2016) Dominik Paquet et al.   NATURE

The mutation significance cutoff: gene-level thresholds for variant predictions

(2016) Yuval Itan et al.   NATURE METHODS

Identification and propagation of haploid human pluripotent stem cells

(2016) Ido Sagi et al.   Nature Protocols

Genome Editing Using Mammalian Haploid Cells

(2015) Takuro Horii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells

(2015) Yasuyoshi Kimura et al.   Scientific Reports

CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

(2015) Puping Liang et al.   Protein & Cell

Haploid Mouse Embryonic Stem Cells: Rapid Genetic Screening and Germline Transmission

(2014) Anton Wutz   Annual Review of Cell and Developmental Biology

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

Parthenogenetic haploid embryonic stem cells produce fertile mice

(2013) Haifeng Wan et al.   CELL RESEARCH

Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells

(2013) Wei Li et al.   Cell Stem Cell

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

(2013) Seung Woo Cho et al.   NATURE BIOTECHNOLOGY

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants

(2012) Daniel Paull et al.   NATURE

Androgenetic haploid embryonic stem cells produce live transgenic mice

(2012) Wei Li et al.   NATURE

Human Genome Sequencing in Health and Disease

(2011) Claudia Gonzaga-Jauregui et al.   Annual Review of Medicine

Derivation of haploid embryonic stem cells from mouse embryos

(2011) Martin Leeb et al.   NATURE

Parthenogenesis as an Approach to Pluripotency: Advantages and Limitations Involved

(2008) Tiziana A. L. Brevini et al.   Stem Cell Reviews and Reports