Covalent Tethering and Residues with Bulky Hydrophobic Side Chains Enable Self-Assembly of Distinct Amyloid Structures

Amyloid Fibrils as Building Blocks for Natural and Artificial Functional Materials

(2016) Tuomas P. J. Knowles et al.   ADVANCED MATERIALS

Polymorphism of Amyloid Fibrils In Vivo

(2016) Karthikeyan Annamalai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral recognition in amyloid fiber growth

(2016) Vladimir Torbeev et al.   JOURNAL OF PEPTIDE SCIENCE

Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils

(2016) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Huntingtin exon 1 fibrils feature an interdigitated β-hairpin–based polyglutamine core

(2016) Cody L. Hoop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril

(2016) Marielle Aulikki Wälti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering Amyloid Fibrils from β-Solenoid Proteins for Biomaterials Applications

(2015) Maria D.R. Peralta et al.   ACS Nano

Synthesis of chemically-tethered amyloid-β segment trimer possessing amyloidogenic properties

(2015) Kiyomichi Shinoda et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Defining the Dynamic Conformational Networks of Cross-β Peptide Assembly

(2015) Jillian E. Smith et al.   ISRAEL JOURNAL OF CHEMISTRY

Alignment of direct detection device micrographs using a robust Optical Flow approach

(2015) Vahid Abrishami et al.   JOURNAL OF STRUCTURAL BIOLOGY

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Amyloid Polymorphism: Structural Basis and Neurobiological Relevance

(2015) Robert Tycko   NEURON

Peptide dimer structure in an Aβ(1–42) fibril visualized with cryo-EM

(2015) Matthias Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling an In-Register, Parallel “Iowa” Aβ Fibril Structure Using Solid-State NMR Data from Labeled Samples with Rosetta

(2015) Nikolaos G. Sgourakis et al.   STRUCTURE

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation

(2014) Anne K. Schütz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Hexameric Peptide Barrel as Building Block of Amyloid-β Protofibrils

(2014) Christofer Lendel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conformational Switching in PolyGln Amyloid Fibrils Resulting from a Single Amino Acid Insertion

(2014) Rick K. Huang et al.   BIOPHYSICAL JOURNAL

Introducing charge transfer functionality into prebiotically relevant β-sheet peptide fibrils

(2014) Denis Ivnitski et al.   CHEMICAL COMMUNICATIONS

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular Structures of Amyloid and Prion Fibrils: Consensus versus Controversy

(2013) Robert Tycko et al.   ACCOUNTS OF CHEMICAL RESEARCH

Intrinsic Structural Heterogeneity and Long-Term Maturation of Amyloid β Peptide Fibrils

(2013) Jianqiang Ma et al.   ACS Chemical Neuroscience

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Infrared, Vibrational Circular Dichroism, and Raman Spectral Simulations for β-Sheet Structures with Various Isotopic Labels, Interstrand, and Stacking Arrangements Using Density Functional Theory

(2013) William R. W. Welch et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural Analyses of Experimental 13C Edited Amide I′ IR and VCD for Peptide β-Sheet Aggregates and Fibrils Using DFT-Based Spectral Simulations

(2013) William R. W. Welch et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling

(2013) Alexander M. Spokoyny et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atomic structure and hierarchical assembly of a cross-  amyloid fibril

(2013) A. W. P. Fitzpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solid-State NMR Spectroscopy of Functional Amyloid from a Fungal Hydrophobin: A Well-Ordered β-Sheet Core Amidst Structural Heterogeneity

(2012) Vanessa K. Morris et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Asymmetric Dimer as the Basic Subunit in Alzheimer’s Disease Amyloid β Fibrils

(2012) Juan Miguel Lopez del Amo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Role of Aromatic Interactions in Amyloid Formation by Islet Amyloid Polypeptide

(2012) Ling-Hsien Tu et al.   BIOCHEMISTRY

Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria

(2012) Lihi Adler-Abramovich et al.   Nature Chemical Biology

Antiparallel  -sheet architecture in Iowa-mutant  -amyloid fibrils

(2012) W. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Engineering of a Secreted, Highly Homogeneous, and Neurotoxic Aβ Dimer

(2011) Andreas Müller-Schiffmann et al.   ACS Chemical Neuroscience

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Mutations That Replace Aromatic Side Chains Promote Aggregation of the Alzheimer’s Aβ Peptide

(2011) Anne H. Armstrong et al.   BIOCHEMISTRY

Protein engineering to stabilize soluble amyloid β-protein aggregates for structural and functional studies

(2011) Torleif Härd   FEBS Journal

A New Structural Model of Aβ40Fibrils

(2011) Ivano Bertini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Disulfide-Linked Amyloid-β Peptide Dimer Forms a Protofibril-like Oligomer through a Distinct Pathway from Amyloid Fibril Formation

(2010) Takahiro Yamaguchi et al.   BIOCHEMISTRY

Amyloid  -Protein Dimers Rapidly Form Stable Synaptotoxic Protofibrils

(2010) B. O'Nuallain et al.   JOURNAL OF NEUROSCIENCE

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural polymorphism of Alzheimer Aβ and other amyloid fibrils

(2010) Marcus Fändrich et al.   Prion

Stabilization of neurotoxic Alzheimer amyloid-  oligomers by protein engineering

(2010) A. Sandberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

β arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils

(2009) Andrey V. Kajava et al.   FASEB JOURNAL

The effect of increasing hydrophobicity on the self-assembly of amphipathic β-sheet peptides

(2009) Charles J. Bowerman et al.   Molecular BioSystems

Interprotofilament interactions between Alzheimer's A 1-42 peptides in amyloid fibrils revealed by cryoEM

(2009) R. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Alzheimer A (1-40) and A (1-42) amyloid fibrils reveals similar protofilament structures

(2009) M. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-Strand Pairing and Amyloid Assembly

(2008) Yan Liang et al.   BIOCHEMISTRY

Molecular structural basis for polymorphism in Alzheimer's  -amyloid fibrils

(2008) A. K. Paravastu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA