Defining the Dynamic Conformational Networks of Cross-β Peptide Assembly

Stable, Metastable, and Kinetically Trapped Amyloid Aggregate Phases

(2014) Tatiana Miti et al.   BIOMACROMOLECULES

pH-controlled aggregation polymorphism of amyloidogenic Aβ(16–22): Insights for obtaining peptide tapes and peptide nanotubes, as function of the N-terminal capping moiety

(2014) Ronald C. Elgersma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Kinetic Approach to the Sequence–Aggregation Relationship in Disease-Related Protein Assembly

(2014) Bogdan Barz et al.   JOURNAL OF PHYSICAL CHEMISTRY B

How to Get Insight into Amyloid Structure and Formation from Infrared Spectroscopy

(2014) Sean D. Moran et al.   Journal of Physical Chemistry Letters

Kinetic Intermediates in Amyloid Assembly

(2014) Chen Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigation of the Aggregation Process of Amyloid-β-(16-22) Peptides and the Dissolution of Intermediate Aggregates

(2014) Dongdong Lin et al.   LANGMUIR

Intermolecular β-Strand Networks Avoid Hub Residues and Favor Low Interconnectedness: A Potential Protection Mechanism against Chain Dissociation upon Mutation

(2014) Giovanni Feverati et al.   PLoS One

Implications of prion adaptation and evolution paradigm for human neurodegenerative diseases

(2014) M Enamul Kabir et al.   Prion

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

(2014) Georg Meisl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of sequence on the molecular assembly of short amyloid peptides

(2014) Victoria A. Wagoner et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Mapping amyloid-β(16-22) nucleation pathways using fluorescence lifetime imaging microscopy

(2014) Neil R. Anthony et al.   Soft Matter

Electrostatic Effects in Filamentous Protein Aggregation

(2013) Alexander K. Buell et al.   BIOPHYSICAL JOURNAL

Infrared, Vibrational Circular Dichroism, and Raman Spectral Simulations for β-Sheet Structures with Various Isotopic Labels, Interstrand, and Stacking Arrangements Using Density Functional Theory

(2013) William R. W. Welch et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural Analyses of Experimental 13C Edited Amide I′ IR and VCD for Peptide β-Sheet Aggregates and Fibrils Using DFT-Based Spectral Simulations

(2013) William R. W. Welch et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Polymorph-Specific Kinetics and Thermodynamics of β-Amyloid Fibril Growth

(2013) Wei Qiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy

(2013) Dorothea Pinotsi et al.   NANO LETTERS

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient  -sheet

(2013) L. E. Buchanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Evolution of Transmissible Prions: The Role of Deformed Templating

(2013) Natallia Makarava et al.   PLoS Pathogens

Remodeling Cross-β Nanotube Surfaces with Peptide/Lipid Chimeras

(2012) Rong Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation

(2012) Samuel I.A. Cohen et al.   JOURNAL OF MOLECULAR BIOLOGY

Driving Forces and Structural Determinants of Steric Zipper Peptide Oligomer Formation Elucidated by Atomistic Simulations

(2012) Dirk Matthes et al.   JOURNAL OF MOLECULAR BIOLOGY

Phase Networks of Cross-β Peptide Assemblies

(2012) W. Seth Childers et al.   LANGMUIR

Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor

(2012) Chris T. Middleton et al.   Nature Chemistry

Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation

(2012) Y. Yoshimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Protein Seeding in Neurodegenerative Diseases

(2012) Lary C. Walker et al.   JAMA Neurology

Structural Characterization of Polyglutamine Fibrils by Solid-State NMR Spectroscopy

(2011) Robert Schneider et al.   JOURNAL OF MOLECULAR BIOLOGY

A Diversity of Assembly Mechanisms of a Generic Amyloid Fold

(2011) Timo Eichner et al.   MOLECULAR CELL

Effects of all-atom force fields on amyloid oligomerization: replica exchange molecular dynamics simulations of the Aβ16–22 dimer and trimer

(2011) Phuong H. Nguyen et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Spatial Extent of Charge Repulsion Regulates Assembly Pathways for Lysozyme Amyloid Fibrils

(2011) Shannon E. Hill et al.   PLoS One

Molecular basis for amyloid-  polymorphism

(2011) J.-P. Colletier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards a Pharmacophore for Amyloid

(2011) Meytal Landau et al.   PLOS BIOLOGY

Probing the Strand Orientation and Registry Alignment in the Propagation of Amyloid Fibrils

(2010) Jason A. Wallace et al.   BIOCHEMISTRY

Environmental Conditions Affect the Kinetics of Nucleation of Amyloid Fibrils and Determine Their Morphology

(2010) Bertrand Morel et al.   BIOPHYSICAL JOURNAL

Direct Observation of Nucleation and Growth in Amyloid Self-Assembly

(2010) Yan Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing aromatic, hydrophobic, and steric effects on the self-assembly of an amyloid-β fragment peptide

(2010) F. Timur Senguen et al.   Molecular BioSystems

Clarifying the influence of core amino acid hydrophobicity, secondary structure propensity, and molecular volume on amyloid-β 16–22 self-assembly

(2010) F. Timur Senguen et al.   Molecular BioSystems

Darwinian Evolution of Prions in Cell Culture

(2010) J. Li et al.   SCIENCE

Existence of Different Structural Intermediates on the Fibrillation Pathway of Human Serum Albumin

(2009) Josué Juárez et al.   BIOPHYSICAL JOURNAL

Simulations of nucleation and elongation of amyloid fibrils

(2009) Jianing Zhang et al.   JOURNAL OF CHEMICAL PHYSICS

Templating Molecular Arrays in Amyloid’s Cross-β Grooves

(2009) W. Seth Childers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamics of locking of peptides onto growing amyloid fibrils

(2009) G. Reddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution

(2009) S.-H. Shim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hofmeister effect on amyloid formation using yeast prion protein

(2009) Victor Yeh et al.   PROTEIN SCIENCE

Cross-Strand Pairing and Amyloid Assembly

(2008) Yan Liang et al.   BIOCHEMISTRY

Assembly of the Asparagine- and Glutamine-Rich Yeast Prions into Protein Fibrils

(2008) Luc Bousset et al.   Current Alzheimer Research

Role of Water in Mediating the Assembly of Alzheimer Amyloid-β Aβ16−22 Protofilaments

(2008) Mary Griffin Krone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facial Symmetry in Protein Self-Assembly

(2008) Anil K. Mehta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY