Efficacy of the sphingosine-1-phosphate receptor agonist fingolimod in animal models of stroke: an updated meta-analysis

Simultaneous revascularization of the occluded internal carotid artery using the Solitaire as a workhorse wire during acute ischemic stroke intervention

(2019) Alexandra R Paul et al.   INTERVENTIONAL NEURORADIOLOGY

Fingolimod enhances the efficacy of delayed alteplase administration in acute ischemic stroke by promoting anterograde reperfusion and retrograde collateral flow

(2018) De-Cai Tian et al.   ANNALS OF NEUROLOGY

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

(2017) Takashi Shichita et al.   NATURE MEDICINE

Fingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia

(2016) Maryam Nazari et al.   BRAIN RESEARCH BULLETIN

Resolving Thromboinflammation in the Brain After Ischemic Stroke?

(2016) Beate E. Kehrel et al.   CIRCULATION

Fingolimod (FTY720) Reduces Cortical Infarction and Neurological Deficits During Ischemic Stroke Through Potential Maintenance of Microvascular Patency

(2016) Michael K. Schuhmann et al.   CURRENT NEUROVASCULAR RESEARCH

Combination of the Immune Modulator Fingolimod With Alteplase in Acute Ischemic StrokeCLINICAL PERSPECTIVE

(2015) Zilong Zhu et al.   CIRCULATION

Progress in Intravenous Thrombolytic Therapy for Acute Stroke

(2015) Randolph S. Marshall   JAMA Neurology

Impact of an immune modulator fingolimod on acute ischemic stroke

(2014) Ying Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meta-analysis of data from animal studies: A practical guide

(2013) H.M. Vesterinen et al.   JOURNAL OF NEUROSCIENCE METHODS

Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke

(2013) Joseph P. Broderick et al.   NEW ENGLAND JOURNAL OF MEDICINE

FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

(2013) Robert Brunkhorst et al.   PLoS One

Fingolimod Reduces Hemorrhagic Transformation Associated With Delayed Tissue Plasminogen Activator Treatment in a Mouse Thromboembolic Model

(2013) Francisco Campos et al.   STROKE

FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection

(2013) Peter Kraft et al.   STROKE

Role of the Sphingosine Metabolism Pathway on Neurons Against Experimental Cerebral Ischemia in Rats

(2013) Yu Hasegawa et al.   Translational Stroke Research

Systematic Review and Meta-Analysis of the Efficacy of Sphingosine-1-Phosphate (S1P) Receptor Agonist FTY720 (Fingolimod) in Animal Models of Stroke

(2012) Junfeng Liu et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

Clinical Pharmacokinetics of Fingolimod

(2011) Olivier J. David et al.   CLINICAL PHARMACOKINETICS

FTY720 Reduces Post-Ischemic Brain Lymphocyte Influx but Does Not Improve Outcome in Permanent Murine Cerebral Ischemia

(2011) Arthur Liesz et al.   PLoS One

Fingolimod provides long-term protection in rodent models of cerebral ischemia

(2010) Ying Wei et al.   ANNALS OF NEUROLOGY

The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia

(2009) Bozena Czech et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Hypoxic Preconditioning-Induced Cerebral Ischemic Tolerance

(2009) Bradley K. Wacker et al.   STROKE

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Activation of Sphingosine 1-Phosphate Receptor-1 by FTY720 Is Neuroprotective After Ischemic Stroke in Rats

(2009) Yu Hasegawa et al.   STROKE

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL