M2 polarization of tumor‐associated macrophages is dependent on integrin β 3 via peroxisome proliferator‐activated receptor‐ γ up‐regulation in breast cancer

Tailoring Nanomaterials for Targeting Tumor‐Associated Macrophages

(2019) Muhammad Ovais et al.   ADVANCED MATERIALS

Triptolide and Its Derivatives as Cancer Therapies

(2019) Pawan Noel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Re-education of macrophages as a therapeutic strategy in cancer

(2019) Joanna Kowal et al.   Immunotherapy

CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

(2019) Luigi Racioppi et al.   Nature Communications

Crosstalk between cancer and immune cells: Role of tumor-associated macrophages in the tumor microenvironment

(2019) Jing Wang et al.   Cancer Medicine

Macrophage-expressed CD51 promotes cancer stem cell properties via the TGF-β1/smad2/3 axis in pancreatic cancer

(2019) Bin Zhang et al.   CANCER LETTERS

Triptolide-loaded nanoparticles targeting breast cancer in vivo with reduced toxicity

(2019) Wei Zheng et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PPARγ induces the gene expression of integrin ανβ5 to promote macrophage M2 polarization

(2018) Qinyu Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential effects of integrin αv knockdown and cilengitide on sensitisation of triple-negative breast cancer and melanoma cells to microtubule poisons

(2018) Nikolina Stojanovic et al.   MOLECULAR PHARMACOLOGY

Downregulation of ZC3H14 driven by chromosome 14q31 deletion promotes hepatocellular carcinoma progression by activating integrin signaling

(2018) Chuxiao Zhang et al.   CARCINOGENESIS

Monocyte Adhesion, Migration, and Extracellular Matrix Breakdown Are Regulated by Integrin αVβ3 inMycobacterium tuberculosisInfection

(2017) Sara Brilha et al.   JOURNAL OF IMMUNOLOGY

Triptolide represses oral cancer cell proliferation, invasion, migration, and angiogenesis in co-inoculation with U937 cells

(2016) Cheng-Yu Yang et al.   Clinical Oral Investigations

PI3Kγ is a molecular switch that controls immune suppression

(2016) Megan M. Kaneda et al.   NATURE

Remodulation of the tumor microenvironment by regulatory T cells

(2015) Chang Liu et al.   Journal for ImmunoTherapy of Cancer

TAB1: A Target of Triptolide in Macrophages

(2014) Yan Lu et al.   CHEMISTRY & BIOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Triptolide induces apoptosis of breast cancer cells via a mechanism associated with the Wnt/β-catenin signaling pathway

(2014) HONGMIN SHAO et al.   Experimental and Therapeutic Medicine

Triptolide Downregulates Treg Cells and the Level of IL-10, TGF-β, and VEGF in Melanoma-Bearing Mice

(2013) Biao Liu et al.   PLANTA MEDICA

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Epidermal α6β4 integrin stimulates the influx of immunosuppressive cells during skin tumor promotion

(2012) Samar W. Maalouf et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Tumour-infiltrating macrophages and clinical outcome in breast cancer

(2011) S M A Mahmoud et al.   JOURNAL OF CLINICAL PATHOLOGY

Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy

(2011) Zhen Huang et al.   JOURNAL OF CONTROLLED RELEASE

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

(2010) Attila Szanto et al.   IMMUNITY