Generic Raman-based calibration models enabling real-time monitoring of cell culture bioreactors

Mid-infrared spectroscopy-based analysis of mammalian cell culture Parameters

(2015) Florian Capito et al.   BIOTECHNOLOGY PROGRESS

Fluorescence-based soft sensor for at situ monitoring of chinese hamster ovary cell cultures

(2014) Kaveh Ohadi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development of a soft-sensor based on multi-wavelength fluorescence spectroscopy and a dynamic metabolic model for monitoring mammalian cell cultures

(2014) Kaveh Ohadi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Glucose concentration control of a fed-batch mammalian cell bioprocess using a nonlinear model predictive controller

(2014) Stephen Craven et al.   JOURNAL OF PROCESS CONTROL

Chemometrics and in-line near infrared spectroscopic monitoring of a biopharmaceutical Chinese hamster ovary cell culture: Prediction of multiple cultivation variables

(2013) Matthieu Clavaud et al.   TALANTA

Automated dynamic fed-batch process and media optimization for high productivity cell culture process development

(2012) Franklin Lu et al.   BIOTECHNOLOGY AND BIOENGINEERING

In situ Raman spectroscopy for simultaneous monitoring of multiple process parameters in mammalian cell culture bioreactors

(2012) Jessica Whelan et al.   BIOTECHNOLOGY PROGRESS

CHO cells in biotechnology for production of recombinant proteins: current state and further potential

(2011) Jee Yon Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

High-End pH-controlled delivery of glucose effectively suppresses lactate accumulation in CHO Fed-batch cultures

(2011) Matthew Gagnon et al.   BIOTECHNOLOGY AND BIOENGINEERING

Design and validation of an innovative soft-sensor for pharmaceuticals freeze-drying monitoring

(2011) Serena Bosca et al.   CHEMICAL ENGINEERING SCIENCE

Process analytical technology (PAT) for biopharmaceutical products

(2010) A. S. Rathore et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Real time monitoring of multiple parameters in mammalian cell culture bioreactors using an in-line Raman spectroscopy probe

(2010) Nicholas R. Abu-Absi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Rapid characterization and quality control of complex cell culture media solutions using raman spectroscopy and chemometrics

(2010) Boyan Li et al.   BIOTECHNOLOGY AND BIOENGINEERING

Advances in on-line monitoring and control of mammalian cell cultures: Supporting the PAT initiative

(2009) A.P. Teixeira et al.   BIOTECHNOLOGY ADVANCES

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Analytical applications of Raman spectroscopy

(2008) Andrzej Kudelski   TALANTA