Nox (NADPH Oxidase) 1, Nox4, and Nox5 Promote Vascular Permeability and Neovascularization in Retinopathy

Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke

(2019) Ana I. Casas et al.   JOURNAL OF CLINICAL INVESTIGATION

NOX5: Molecular biology and pathophysiology

(2019) Rhian M. Touyz et al.   EXPERIMENTAL PHYSIOLOGY

Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse

(2019) Jay C. Jha et al.   DIABETOLOGIA

Redox Control of Angiogenesis

(2018) Katrin Schröder   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

Intravitreal administration of endothelin type A receptor or endothelin type B receptor antagonists attenuates hypertensive and diabetic retinopathy in rats

(2018) Saeed F. Alrashdi et al.   EXPERIMENTAL EYE RESEARCH

Podocyte NADPH Oxidase 5 Promotes Renal Inflammation Regulated by the Toll-Like Receptor Pathway

(2018) Chet E. Holterman et al.   ANTIOXIDANTS & REDOX SIGNALING

Müller cells and diabetic retinopathy

(2017) Brandon A. Coughlin et al.   VISION RESEARCH

The inner blood-retinal barrier: Cellular basis and development

(2017) Mónica Díaz-Coránguez et al.   VISION RESEARCH

Early changes in system xc− and glutathione in the retina of diabetic rats

(2016) Raul Carpi-Santos et al.   EXPERIMENTAL EYE RESEARCH

NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages

(2016) Jong-Seok Moon et al.   NATURE MEDICINE

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

(2015) Sebastian Altenhöfer et al.   ANTIOXIDANTS & REDOX SIGNALING

Are reactive oxygen species still the basis for diabetic complications?

(2015) Elyse Di Marco et al.   CLINICAL SCIENCE

Novel Therapies in Development for Diabetic Macular Edema

(2015) Aniruddha Agarwal et al.   Current Diabetes Reports

Inhibition of NOX1/4 with GKT137831: a potential novel treatment to attenuate neuroglial cell inflammation in the retina

(2015) Devy Deliyanti et al.   Journal of Neuroinflammation

NADPH Oxidase 4-Derived H2O2Promotes Aberrant Retinal Neovascularization via Activation of VEGF Receptor 2 Pathway in Oxygen-Induced Retinopathy

(2015) Jingming Li et al.   Journal of Diabetes Research

NADPH Oxidase–Generated Reactive Oxygen Species Are Required for Stromal Cell–Derived Factor-1α–Stimulated Angiogenesis

(2014) Xinchun Pi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

NADPH Oxidase, NOX1, Mediates Vascular Injury in Ischemic Retinopathy

(2013) Jennifer L. Wilkinson-Berka et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy

(2013) Jennifer L. Wilkinson-Berka et al.   CLINICAL SCIENCE

Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune–inflammatory responses in diabetic Apoe −/− mice

(2013) E. Di Marco et al.   DIABETOLOGIA

Nephropathy and Elevated BP in Mice with Podocyte-Specific NADPH Oxidase 5 Expression

(2013) C. E. Holterman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury

(2013) Modesto Rojas et al.   PLoS One

Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes

(2012) Mona Sedeek et al.   CLINICAL SCIENCE

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

(2010) A. G. Miller et al.   DIABETES

Inhibition of Reactive Oxygen Species by Lovastatin Downregulates Vascular Endothelial Growth Factor Expression and Ameliorates Blood-Retinal Barrier Breakdown in db/db Mice: Role of NADPH Oxidase 4

(2010) J. Li et al.   DIABETES

Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life

(2010) Przemyslaw Sapieha et al.   JOURNAL OF CLINICAL INVESTIGATION

Diabetic Retinal Neurodegeneration Is Associated With Mitochondrial Oxidative Stress and Is Improved by an Angiotensin Receptor Blocker in a Model Combining Hypertension and Diabetes

(2009) K. C. Silva et al.   DIABETES

Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials

(2008) Nish Chaturvedi et al.   LANCET

Influence of rosuvastatin on the NAD(P)H oxidase activity in the retina and electroretinographic response of spontaneously hypertensive rats

(2007) P Sicard et al.   BRITISH JOURNAL OF PHARMACOLOGY