Approaches for recombinant human factor IX production in serum-free suspension cultures

Serum-free cell culture: the serum-free media interactive online database

(2016) Daniel Brunner   ALTEX-Alternatives to Animal Experimentation

Functional expression of the human coagulation factor IX using heterologous signal peptide and propeptide sequences in mammalian cell line

(2015) Shohreh Khorshidi et al.   BIOTECHNOLOGY LETTERS

Expression and characterization of a novel human recombinant factor IX molecule with enhanced in vitro and in vivo clotting activity

(2015) Eloïse Perot et al.   THROMBOSIS RESEARCH

Improved Expression of Recombinant Human Factor IX by Co-expression of GGCX, VKOR and Furin

(2014) Jianming Liu et al.   PROTEIN JOURNAL

HEK293 cell culture media study towards bioprocess optimization: Animal derived component free and animal derived component containing platforms

(2013) Leticia Liste-Calleja et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Generation of HIV-1 Gag VLPs by transient transfection of HEK 293 suspension cell cultures using an optimized animal-derived component free medium

(2013) Laura Cervera et al.   JOURNAL OF BIOTECHNOLOGY

Production platforms for biotherapeutic glycoproteins. Occurrence, impact, and challenges of non-human sialylation

(2012) Darius Ghaderi et al.   Biotechnology & Genetic Engineering Reviews

Comparison of commercial serum-free media for CHO-K1 cell growth and monoclonal antibody production

(2012) Maria Elisa Rodrigues et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Human cells: New platform for recombinant therapeutic protein production

(2012) Kamilla Swiech et al.   PROTEIN EXPRESSION AND PURIFICATION

Human hepatoma cell line HuH-7 is an effective cellular system to produce recombinant factor IX with improved post-translational modifications

(2012) Nathalie Enjolras et al.   THROMBOSIS RESEARCH

Stable and high-level production of recombinant Factor IX in human hepatic cell line

(2011) Andrielle de Castilho Fernandes et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Expression of biologically active human clotting factor IX in Drosophila S2 cells: γ-carboxylation of a human vitamin K-dependent protein by the insect enzyme

(2011) Jafar Vatandoost et al.   BIOTECHNOLOGY PROGRESS

Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII

(2011) Kamilla Swiech et al.   BMC BIOTECHNOLOGY

Production of Inactivated Influenza H5N1 Vaccines from MDCK Cells in Serum-Free Medium

(2011) Alan Yung-Chih Hu et al.   PLoS One

Generation of a novel factor IX with augmented clotting activitiesin vitroandin vivo

(2010) C. N. LIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Forum on: the role of recombinant factor VIII in children with severe haemophilia A

(2009) M. FRANCHINI et al.   HAEMOPHILIA

Sex hormones affect the production of recombinant Factor IX in CHO and HEK-293 cell lines

(2008) Nazanin Dadehbeigi et al.   BIOTECHNOLOGY LETTERS

Analysis of the N-glycans of recombinant human Factor IX purified from transgenic pig milk

(2008) Geun-Cheol Gil et al.   GLYCOBIOLOGY

The carboxylation efficiency of the vitamin K-dependent clotting factors: studies with factor IX

(2008) M. BLOSTEIN et al.   HAEMOPHILIA