Effects of kynurenic acid analogue 1 (KYNA-A1) in nitroglycerin-induced hyperalgesia: Targets and anti-migraine mechanisms

Manipulating Kynurenic Acid Levels in the Brain – On the Edge Between Neuroprotection and Cognitive Dysfunction

(2017) Levente Szalardy et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The modulatory effect of anandamide on nitroglycerin-induced sensitization in the trigeminal system of the rat

(2016) Gábor Nagy-Grócz et al.   CEPHALALGIA

Activity-triggered tetrapartite neuron–glial interactions following peripheral injury

(2016) Ke Ren et al.   CURRENT OPINION IN PHARMACOLOGY

Calcitonin gene-related peptide mediates an inflammatory response in Schwann cells via cAMP-dependent ERK signaling cascade

(2016) Kannika Permpoonputtana et al.   LIFE SCIENCES

Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood–brain barrier

(2015) Sajedeh Eftekhari et al.   BRAIN RESEARCH

Evaluation of ADMA-DDAH-NOS axis in specific brain areas following nitroglycerin administration: study in an animal model of migraine

(2015) Rosaria Greco et al.   JOURNAL OF HEADACHE AND PAIN

TRPA1, NMDA receptors and nitric oxide mediate mechanical hyperalgesia induced by local injection of magnesium sulfate into the rat hind paw

(2015) Dragana P. Srebro et al.   PHYSIOLOGY & BEHAVIOR

Inhibition of Opioid Receptor Mediated G-Protein Activity After Chronic Administration of Kynurenic Acid and its Derivative without Direct Binding to Opioid Receptors

(2014) Ferenc Zador et al.   CNS & Neurological Disorders-Drug Targets

Activation of CB2 receptors as a potential therapeutic target for migraine: evaluation in an animal model

(2014) Rosaria Greco et al.   JOURNAL OF HEADACHE AND PAIN

Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus

(2014) María T Santamarta et al.   JOURNAL OF PSYCHOPHARMACOLOGY

A rat model of full thickness thermal injury characterized by thermal hyperalgesia, mechanical allodynia, pronociceptive peptide release and tramadol analgesia

(2013) Marcie Fowler et al.   BURNS

Nitric oxide synthase, calcitonin gene-related peptide and NK-1 receptor mechanisms are involved in GTN-induced neuronal activation

(2013) Roshni Ramachandran et al.   CEPHALALGIA

Migraine pathophysiology: Anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain

(2013) Rodrigo Noseda et al.   PAIN

Evidence for Glutamate as a Neuroglial Transmitter within Sensory Ganglia

(2013) Ling-Hsuan Kung et al.   PLoS One

Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: Facts and challenges

(2012) Edson X. Albuquerque et al.   BIOCHEMICAL PHARMACOLOGY

MK801 attenuates secondary injury in a mouse experimental compression model of spinal cord trauma

(2011) Emanuela Esposito et al.   BMC NEUROSCIENCE

New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

(2011) Jan Hoffmann et al.   Current Treatment Options in Neurology

Identification of Cytokines and Signaling Proteins Differentially Regulated by Sumatriptan/Naproxen

(2011) Carrie V. Vause et al.   HEADACHE

Time-course of kynurenic acid concentration in mouse serum following the administration of a novel kynurenic acid analog

(2011) Dénes Zádori et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The Mu-Opioid Receptor and the NMDA Receptor Associate in PAG Neurons: Implications in Pain Control

(2011) María Rodríguez-Muñoz et al.   NEUROPSYCHOPHARMACOLOGY

Fos expression induced by activation of NMDA and neurokinin-1 receptors in the trigeminal subnucleus caudalis in vitro: Role of protein kinases

(2010) Ceri E. Allen et al.   BRAIN RESEARCH

Increase in CGRP- and nNOS-immunoreactive neurons in the rat trigeminal ganglion after infusion of an NO donor

(2010) Anne Dieterle et al.   CEPHALALGIA

Oral nitric-oxide donor glyceryl-trinitrate induces sensitization in spinal cord pain processing in migraineurs: A double-blind, placebo-controlled, cross-over study

(2010) Armando Perrottal et al.   EUROPEAN JOURNAL OF PAIN

Nitric Oxide Synthase Modulates CFA-Induced Thermal Hyperalgesia through Cytokine Regulation in Mice

(2010) Yong Chen et al.   Molecular Pain

Increase in NADPH-Diaphorase-Positive and Neuronal NO Synthase Immunoreactive Neurons in the Rat Spinal Trigeminal Nucleus Following Infusion of a NO Donor—Evidence for a Feed-Forward Process in NO Production Involved in Trigeminal Nociception

(2009) PM Schlechtweg et al.   CEPHALALGIA

Pharmacological Manipulation of Kynurenic Acid

(2009) Sophie Erhardt et al.   CNS DRUGS

Kynurenate Derivative Attenuates the Nitroglycerin-Induced CamKIIα and CGRP Expression Changes

(2009) Enikő Vámos et al.   HEADACHE

l-kynurenine combined with probenecid and the novel synthetic kynurenic acid derivative attenuate nitroglycerin-induced nNOS in the rat caudal trigeminal nucleus

(2009) Enikő Vámos et al.   NEUROPHARMACOLOGY

MAP kinase and pain

(2008) Ru-Rong Ji et al.   BRAIN RESEARCH REVIEWS

Cytokine regulation in animal models of neuropathic pain and in human diseases

(2008) Nurcan Üçeyler et al.   NEUROSCIENCE LETTERS

The kynurenate analog SZR-72 prevents the nitroglycerol-induced increase of c-fos immunoreactivity in the rat caudal trigeminal nucleus: Comparative studies of the effects of SZR-72 and kynurenic acid

(2008) E. Knyihar-Csillik et al.   NEUROSCIENCE RESEARCH