HMGB1 impairs endothelium‐dependent relaxation in diabetes through TLR4/eNOS pathway

Elevated high-density lipoprotein in adolescents with Type 1 diabetes is associated with endothelial dysfunction in the presence of systemic inflammation

(2019) Scott T Chiesa et al.   EUROPEAN HEART JOURNAL

Intensive Glucose Control in Patients with Type 2 Diabetes — 15-Year Follow-up

(2019) Peter D. Reaven et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association between Radiation Exposure and Endothelium-Dependent Vasodilation: Results from Clinical and Experimental Studies

(2019) Zhaowei Zhu et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

High-mobility group box 1 protein (HMGB1) operates as an alarmin outside as well as inside cells

(2018) Ulf Andersson et al.   SEMINARS IN IMMUNOLOGY

Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

(2018) Raminderjit Kaur et al.   Cardiovascular Diabetology

2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2019

(2018)   DIABETES CARE

HMGB1 and repair: focus on the heart

(2018) Laura Pellegrini et al.   PHARMACOLOGY & THERAPEUTICS

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Thirty Years of Saying NO

(2016) Paul M. Vanhoutte et al.   CIRCULATION RESEARCH

Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes

(2016) Theodora Szasz et al.   DIABETES

Vascular effects of linagliptin in non-obese diabetic mice are glucose-independent and involve positive modulation of the endothelial nitric oxide synthase (eNOS)/caveolin-1 (CAV-1) pathway

(2016) Valentina Vellecco et al.   DIABETES OBESITY & METABOLISM

Hypothermia inhibits the propagation of acute ischemic injury by inhibiting HMGB1

(2016) Jung Ho Lee et al.   Molecular Brain

Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming

(2015) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension

(2015) R Hernanz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Uncoupling Caveolae From Intracellular Signaling In VivoNovelty and Significance

(2015) Jan R. Kraehling et al.   CIRCULATION RESEARCH

Plasma HMGB-1 Levels in Subjects with Obesity and Type 2 Diabetes: A Cross-Sectional Study in China

(2015) Hang Wang et al.   PLoS One

Bilirubin inhibits the up-regulation of inducible nitric oxide synthase by scavenging reactive oxygen species generated by the toll-like receptor 4-dependent activation of NADPH oxidase

(2015) Gila Idelman et al.   Redox Biology

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-  Production in Human Monocytes

(2014) J. H. Youn et al.   JOURNAL OF IMMUNOLOGY

Hypoxic Trophoblast HMGB1 Induces Endothelial Cell Hyperpermeability via the TRL-4/Caveolin-1 Pathway

(2014) Rongzhen Jiang et al.   JOURNAL OF IMMUNOLOGY

High-mobility group box-1 and its role in angiogenesis

(2014) S. Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of Toll-like Receptors 2 and 4 in Mediating Endothelial Dysfunction and Arterial Remodeling in Primary Arterial Antiphospholipid Syndrome

(2014) Ygal Benhamou et al.   Arthritis & Rheumatology

Toll-Like Receptor 4 Mutation Protects Obese Mice Against Endothelial Dysfunction by Decreasing NADPH Oxidase Isoforms 1 and 4

(2013) Chao-Fan Liang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors

(2013) Christian Rask-Madsen et al.   Cell Metabolism

High-mobility group protein B1: a new biomarker of metabolic syndrome in obese children

(2013) Teresa Arrigo et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Increased serum HMGB1 related with HbA1c in coronary artery disease with type 2 diabetes mellitus

(2013) Dongdong Zhao et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

HMGB1 and TLR4 mediate skeletal muscle recovery in a murine model of hindlimb ischemia

(2013) Ulka Sachdev et al.   JOURNAL OF VASCULAR SURGERY

An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies

(2013) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling

(2013) Ibrahim Yazji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of neointimal hyperplasia in the rat carotid artery injury model by a HMGB1 inhibitor

(2012) Jing Chen et al.   ATHEROSCLEROSIS

High Mobility Group Box 1 Inhibits Human Pulmonary Artery Endothelial Cell Migration via a Toll-like Receptor 4- and Interferon Response Factor 3-dependent Mechanism(s)

(2012) Eileen M. Bauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-mobility group box family of proteins: ligand and sensor for innate immunity

(2012) Hideyuki Yanai et al.   TRENDS IN IMMUNOLOGY

High-Mobility Group Box 1, Oxidative Stress, and Disease

(2010) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING