Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll‐like 4 receptor signaling

Correction to: Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance

(2018) Mingzhu He et al.   MOLECULAR MEDICINE

Macrophage Markers are Poorly Associated with Liver Histology in Children with Non-Alcoholic Fatty Liver Disease

(2018) Konstantin Kazankov et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Chondroitin sulfate–mediated N-cadherin/β-catenin signaling is associated with basal-like breast cancer cell invasion

(2017) Satomi Nadanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparan sulfate proteoglycans fine-tune macrophage inflammation via IFN-β

(2015) Philip L.S.M. Gordts et al.   CYTOKINE

Reducing Macrophage Proteoglycan Sulfation Increases Atherosclerosis and Obesity through Enhanced Type I Interferon Signaling

(2014) Philip L.S.M. Gordts et al.   Cell Metabolism

An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages

(2014) Anthony Troegeler et al.   IMMUNOLOGY AND CELL BIOLOGY

Endocan: A novel circulating proteoglycan

(2014) Arunava Kali et al.   INDIAN JOURNAL OF PHARMACOLOGY

Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

(2014) Adil Mardinoglu et al.   Nature Communications

Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes

(2013) Satomi Nadanaka et al.   BIOCHEMICAL JOURNAL

Biosynthesis and function of chondroitin sulfate

(2013) Tadahisa Mikami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

EXTL2, a Member of theEXTFamily of Tumor Suppressors, Controls Glycosaminoglycan Biosynthesis in a Xylose Kinase-dependent Manner

(2013) Satomi Nadanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma

(2013) Masato Fujii et al.   Medical Molecular Morphology

Glycosaminoglycan Overproduction in the Aorta Increases Aortic Calcification in Murine Chronic Kidney Disease

(2013) Eko Purnomo et al.   Journal of the American Heart Association

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

(2012) Dianne H. Dapito et al.   CANCER CELL

Dermatan Sulfate Is Involved in the Tumorigenic Properties of Esophagus Squamous Cell Carcinoma

(2012) M. A. Thelin et al.   CANCER RESEARCH

Glycosaminoglycans: key players in cancer cell biology and treatment

(2012) Nikos Afratis et al.   FEBS Journal

Biglycan

(2012) Madalina V. Nastase et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Down-regulation of Chondroitin 4-O-Sulfotransferase-1 by Wnt Signaling Triggers Diffusion of Wnt-3a

(2010) Satomi Nadanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

Important role of heparan sulfate in postnatal islet growth and insulin secretion

(2009) Iwao Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

(2009) Andrea Babelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparan Sulphate Biosynthesis and Disease

(2008) Satomi Nadanaka et al.   JOURNAL OF BIOCHEMISTRY

Chondroitin 4-O-Sulfotransferase-1 Modulates Wnt-3a Signaling through Control of E Disaccharide Expression of Chondroitin Sulfate

(2008) Satomi Nadanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE