Challenges in the development of next-generation antibiotics: opportunities of small molecules mimicking mode of action of host-defense peptides

Outer membrane interaction kinetics of new polymyxin B analogs in Gram-negative bacilli

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Rational Design of Dimeric Lysine N-Alkylamides as Potent and Broad-Spectrum Antibacterial Agents

(2018) Youhong Niu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Membrane-Active Hydantoin Derivatives as Antibiotic Agents

(2017) Ma Su et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanisms and consequences of bacterial resistance to antimicrobial peptides

(2016) D.I. Andersson et al.   DRUG RESISTANCE UPDATES

Small Antimicrobial Agents Based on Acylated Reduced Amide Scaffold

(2016) Peng Teng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Turning Defense into Offense: Defensin Mimetics as Novel Antibiotics Targeting Lipid II

(2013) Kristen M. Varney et al.   PLoS Pathogens

Synthetic Mimics of Antimicrobial Peptides from Triaryl Scaffolds

(2011) Hitesh D. Thaker et al.   JOURNAL OF MEDICINAL CHEMISTRY

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

Role of the Conformational Rigidity in the Design of Biomimetic Antimicrobial Compounds

(2010) Andrey Ivankin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

(2009) S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA