Turning Defense into Offense: Defensin Mimetics as Novel Antibiotics Targeting Lipid II

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

CHARMM Additive All-Atom Force Field for Carbohydrate Derivatives and Its Utility in Polysaccharide and Carbohydrate–Protein Modeling

(2011) Olgun Guvench et al.   Journal of Chemical Theory and Computation

CHARMM Additive All-Atom Force Field for Phosphate and Sulfate Linked to Carbohydrates

(2011) Sairam S. Mallajosyula et al.   Journal of Chemical Theory and Computation

Structural determinants of antimicrobial activity in polymers which mimic host defense peptides

(2010) Edmund F. Palermo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II

(2010) Erik de Leeuw et al.   FEBS LETTERS

Human  -Defensin 3 Inhibits Cell Wall Biosynthesis in Staphylococci

(2010) V. Sass et al.   INFECTION AND IMMUNITY

Trp-26 Imparts Functional Versatility to Human α-Defensin HNP1

(2010) Gang Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insight into Invertebrate Defensin Mechanism of Action

(2010) Paulina Schmitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Synthetic Mimics of Antimicrobial Peptides-A Versatile Ring-Opening Metathesis Polymerization Based Platform for the Synthesis of Selective Antibacterial and Cell-Penetrating Polymers

(2009) Karen Lienkamp et al.   CHEMISTRY-A EUROPEAN JOURNAL

Through the Looking Glass, Mechanistic Insights from Enantiomeric Human Defensins

(2009) Gang Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY