Polyphosphate as a metabolic fuel in Metazoa: A foundational breakthrough invention for biomedical applications

Nonenzymatic Transformation of Amorphous CaCO3into Calcium Phosphate Mineral after Exposure to Sodium Phosphate in Vitro: Implications for in Vivo Hydroxyapatite Bone Formation

(2015) Werner E. G. Müller et al.   CHEMBIOCHEM

Retinol encapsulated into amorphous Ca2+ polyphosphate nanospheres acts synergistically in MC3T3-E1 cells

(2015) Werner E.G. Müller et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Amorphous Ca2+ polyphosphate nanoparticles regulate the ATP level in bone-like SaOS-2 cells

(2015) W. E. G. Muller et al.   JOURNAL OF CELL SCIENCE

Polyphosphate: A Morphogenetically Active Implant Material Serving as Metabolic Fuel for Bone Regeneration

(2015) Werner E. G. Müller et al.   MACROMOLECULAR BIOSCIENCE

A new polyphosphate calcium material with morphogenetic activity

(2015) Werner E.G. Müller et al.   MATERIALS LETTERS

Protein Polyphosphorylation of Lysine Residues by Inorganic Polyphosphate

(2015) Cristina Azevedo et al.   MOLECULAR CELL

Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use

(2015) Jaromir Pastorek et al.   SEMINARS IN CANCER BIOLOGY

Polyphosphate accelerates factor V activation by factor XIa

(2015) Sharon Choi et al.   THROMBOSIS AND HAEMOSTASIS

A new printable and durable N,O-carboxymethyl chitosan–Ca2+–polyphosphate complex with morphogenetic activity

(2015) Werner E. G. Müller et al.   Journal of Materials Chemistry B

Positively-Charged Semi-Tunnel Is a Structural and Surface Characteristic of Polyphosphate-Binding Proteins: An In-Silico Study

(2015) Zheng Zachory Wei et al.   PLoS One

Functions of inorganic polyphosphates in eukaryotic cells: a coat of many colours

(2014) Cristina Azevedo et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Engineering a morphogenetically active hydrogel for bioprinting of bioartificial tissue derived from human osteoblast-like SaOS-2 cells

(2014) Meik Neufurth et al.   BIOMATERIALS

Biosilica-loaded poly(ϵ-caprolactone) nanofibers mats provide a morphogenetically active surface scaffold for the growth and mineralization of the osteoclast-related SaOS-2 cells

(2014) Werner E.G. Müller et al.   Biotechnology Journal

Mitochondrial dysfunction: a neglected component of skin diseases

(2014) René G. Feichtinger et al.   EXPERIMENTAL DERMATOLOGY

Osteogenic Cell Cultures Cannot Utilize Exogenous Sources of Synthetic Polyphosphate for Mineralization

(2014) Marianne B. Ariganello et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Morphogenetic Study on the Maturation of Osteoblastic Cell as Induced by Inorganic Polyphosphate

(2014) Kaori Tsutsumi et al.   PLoS One

Enzyme-based biosilica and biocalcite: biomaterials for the future in regenerative medicine

(2014) Xiaohong Wang et al.   TRENDS IN BIOTECHNOLOGY

Neuronal Signaling through Endocytosis

(2014) K. E. Cosker et al.   Cold Spring Harbor Perspectives in Biology

Biocalcite, a multifunctional inorganic polymer: Building block for calcareous sponge spicules and bioseed for the synthesis of calcium phosphate-based bone

(2014) Xiaohong Wang et al.   Beilstein Journal of Nanotechnology

Inositol pyrophosphates: between signalling and metabolism

(2013) Miranda S. C. Wilson et al.   BIOCHEMICAL JOURNAL

Modulation of the Initial Mineralization Process of SaOS-2 Cells by Carbonic Anhydrase Activators and Polyphosphate

(2013) Xiaohong Wang et al.   CALCIFIED TISSUE INTERNATIONAL

Signalling properties of inorganic polyphosphate in the mammalian brain

(2013) Kira M. Holmström et al.   Nature Communications

Gene expression analysis of mTOR pathway: association with human longevity

(2012) Willemijn M. Passtoors et al.   AGING CELL

Nocturnin in the demospongeSuberites domuncula: a potential circadian clock protein controlling glycogenin synthesis in sponges

(2012) Werner E. G. Müller et al.   BIOCHEMICAL JOURNAL

Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia

(2012) B. Yu et al.   BLOOD

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

(2012) J. H. Morrissey et al.   BLOOD

Cellular Uptake Mechanisms and Endosomal Trafficking of Supercharged Proteins

(2012) David B. Thompson et al.   CHEMISTRY & BIOLOGY

Bio-silica and bio-polyphosphate: applications in biomedicine (bone formation)

(2012) Xiaohong Wang et al.   CURRENT OPINION IN BIOTECHNOLOGY

Activation of the FGF signaling pathway and subsequent induction of mesenchymal stem cell differentiation by inorganic polyphosphate

(2012) Yumi Kawazoe et al.   International Journal of Biological Sciences

Polyphosphate: a link between platelets, coagulation and inflammation

(2012) James H. Morrissey   INTERNATIONAL JOURNAL OF HEMATOLOGY

Structural annotation of human carbonic anhydrases

(2012) Mayank Aggarwal et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inorganic polyphosphate is a potent activator of the mitochondrial permeability transition pore in cardiac myocytes

(2012) Lea K. Seidlmayer et al.   JOURNAL OF GENERAL PHYSIOLOGY

Identification and characterization of a human mitochondrial NAD kinase

(2012) Kazuto Ohashi et al.   Nature Communications

Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2+ level in osteoblasts (SaOS-2 cells) in vitro

(2011) Werner E.G. Müller et al.   Acta Biomaterialia

Role of Inorganic Polyphosphate for Cardiac Mitochondrial Function in Ischemia/Reperfusion

(2011) Lea K. Seidlmayer et al.   BIOPHYSICAL JOURNAL

Acidocalcisomes

(2011) Roberto Docampo et al.   CELL CALCIUM

Identification of an Evolutionarily Conserved Family of Inorganic Polyphosphate Endopolyphosphatases

(2011) Annalisa Lonetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP distribution and localization of mitochondria in Suberites domuncula (Olivi 1792) tissue

(2011) L. Lukic-Bilela et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation

(2010) Glenda Parra-Bonilla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells

(2010) Matthias Wiens et al.   BIOMATERIALS

Osteogenic Potential of Biosilica on Human Osteoblast-Like (SaOS-2) Cells

(2010) Matthias Wiens et al.   CALCIFIED TISSUE INTERNATIONAL

The emergence of phosphate as a specific signaling molecule in bone and other cell types in mammals

(2010) Solmaz Khoshniat et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sulfide induces phosphate release from polyphosphate in cultures of a marine Beggiatoa strain

(2010) Jörg Brock et al.   ISME Journal

Inorganic Polyphosphate and Energy Metabolism in Mammalian Cells

(2010) Evgeny Pavlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic fuels: regulating fluxes to select mix

(2010) J.-M. Weber   JOURNAL OF EXPERIMENTAL BIOLOGY

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recent Discoveries on the Roles of Polyphosphates in Plants

(2010) Manfredo J. Seufferheld et al.   PLANT MOLECULAR BIOLOGY REPORTER

Inorganic Polyphosphate: Essential for Growth and Survival

(2009) Narayana N. Rao et al.   Annual Review of Biochemistry

Use of Wound-Protection System and Postoperative Wound-Infection Rates in Open Appendectomy

(2009) Pamela Lee   ARCHIVES OF SURGERY

Inorganic phosphate regulates Glvr-1 and -2 expression: Role of calcium and ERK1/2

(2009) Y. Wittrant et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial calcium as a key regulator of mitochondrial ATP production in mammalian cells

(2009) Elinor J. Griffiths et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors

(2009) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease

(2009) Lars Muhl et al.   FEBS Journal

Inhibitors of clathrin-dependent endocytosis enhance TGF  signaling and responses

(2009) C.-L. Chen et al.   JOURNAL OF CELL SCIENCE

Catalytic Core of a Membrane-Associated Eukaryotic Polyphosphate Polymerase

(2009) M. Hothorn et al.   SCIENCE

Mitochondrial fusion and division: Regulation and role in cell viability

(2009) Giovanni Benard et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Human Metastasis Regulator Protein H-Prune is a Short-Chain Exopolyphosphatase†

(2008) Marko Tammenkoski et al.   BIOCHEMISTRY

The AP3 adaptor is involved in the transport of membrane proteins to acidocalcisomes of Leishmania

(2008) S. Besteiro et al.   JOURNAL OF CELL SCIENCE

Modulation of mitochondrial morphology by bioenergetics defects in primary human fibroblasts

(2008) O. Guillery et al.   NEUROMUSCULAR DISORDERS

Paleoenvironmental implications of high-density records in Co-rich seamount crusts from the Pacific Ocean

(2008) XiaoHong Wang et al.   Science in China. Series D, Earth sciences / Chinese Academy of Sciences