Bacterial membrane vesicles: Biogenesis, immune regulation and pathogenesis

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

(2016) Sivapriya Kailasan Vanaja et al.   CELL

Extracellular Vesicles from Trypanosoma brucei Mediate Virulence Factor Transfer and Cause Host Anemia

(2016) Anthony J. Szempruch et al.   CELL

Porphyromonas gingivalis Outer Membrane Vesicles Induce Selective Tumor Necrosis Factor Tolerance in a Toll-Like Receptor 4- and mTOR-Dependent Manner

(2016) Tobias Waller et al.   INFECTION AND IMMUNITY

Cytotoxic and Inflammatory Responses Induced by Outer Membrane Vesicle-Associated Biologically Active Proteases from Vibrio cholerae

(2016) Ayan Mondal et al.   INFECTION AND IMMUNITY

Naturally Occurring IgG Antibodies Provide Innate Protection against Vibrio cholerae Bacteremia by Recognition of the Outer Membrane Protein U

(2016) Kyaw Min Aung et al.   Journal of Innate Immunity

Outer membrane vesicles displaying engineered glycotopes elicit protective antibodies

(2016) Linxiao Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

(2016) H. Chu et al.   SCIENCE

Development of a cost-effective vaccine candidate with outer membrane vesicles of a tolA-disrupted Shigella boydii strain

(2016) Soma Mitra et al.   VACCINE

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

(2016) Merijn L.M. Salverda et al.   VACCINE

Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice

(2016) C. Garrett Rappazzo et al.   VACCINE

LPS Remodeling Triggers Formation of Outer Membrane Vesicles in Salmonella

(2016) Wael Elhenawy et al.   mBio

Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms

(2016) Lynne Turnbull et al.   Nature Communications

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

(2016) Sandro Roier et al.   Nature Communications

A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles

(2016) Katja Koeppen et al.   PLoS Pathogens

Extracellular vesicle proteomes reflect developmental phases of Bacillus subtilis

(2016) Yeji Kim et al.   Clinical Proteomics

Differential Responses of Pattern Recognition Receptors to Outer Membrane Vesicles of Three Periodontal Pathogens

(2016) Jessica D. Cecil et al.   PLoS One

Characterisation of the Immunomodulatory Effects of Meningococcal Opa Proteins on Human Peripheral Blood Mononuclear Cells and CD4+ T Cells

(2016) Claire Jones et al.   PLoS One

Glycoengineered Outer Membrane Vesicles: A Novel Platform for Bacterial Vaccines

(2016) Nancy L. Price et al.   Scientific Reports

Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles

(2015) Christina A. Hickey et al.   Cell Host & Microbe

Increased Outer Membrane Vesicle Formation in aHelicobacter pylori tolBMutant

(2015) Lorinda Turner et al.   HELICOBACTER

Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype

(2015) Sujittra Chaiyadet et al.   JOURNAL OF INFECTIOUS DISEASES

Outer membrane vesicles isolated from two clinical Acinetobacter baumannii strains exhibit different toxicity and proteome characteristics

(2015) Zhi-Tao Li et al.   MICROBIAL PATHOGENESIS

The Human PathogenStreptococcus pyogenesReleases Lipoproteins as Lipoprotein-rich Membrane Vesicles

(2015) Massimiliano Biagini et al.   MOLECULAR & CELLULAR PROTEOMICS

Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

(2015) Lisa Brown et al.   NATURE REVIEWS MICROBIOLOGY

Active Immunization with Extracellular Vesicles Derived from Staphylococcus aureus Effectively Protects against Staphylococcal Lung Infections, Mainly via Th1 Cell-Mediated Immunity

(2015) Seng Jin Choi et al.   PLoS One

Altered host immune responses to membrane vesicles from Salmonella and Gram-negative pathogens

(2015) Richard C. Laughlin et al.   VACCINE

Virulence from vesicles: Novel mechanisms of host cell injury by Escherichia coli O104:H4 outbreak strain

(2015) Lisa Kunsmann et al.   Scientific Reports

NlpI-mediated modulation of outer membrane vesicle production through peptidoglycan dynamics inEscherichia coli

(2015) Carmen Schwechheimer et al.   MicrobiologyOpen

The extracellular RNA complement ofEscherichia coli

(2015) Anubrata Ghosal et al.   MicrobiologyOpen

Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

(2015) Barbara Bottazzi et al.   PLoS One

Functional Advantages of Porphyromonas gingivalis Vesicles

(2015) Meng-Hsuan Ho et al.   PLoS One

Membrane vesicle-mediated release of bacterial RNA

(2015) Annika E. Sjöström et al.   Scientific Reports

Modulation of bacterial outer membrane vesicle production by envelope structure and content

(2014) Carmen Schwechheimer et al.   BMC MICROBIOLOGY

The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling

(2014) Aaron T. Irving et al.   Cell Host & Microbe

Helicobacter pylori Membrane Vesicles Stimulate Innate Pro- and Anti-Inflammatory Responses and Induce Apoptosis in Jurkat T Cells

(2014) Jody Winter et al.   INFECTION AND IMMUNITY

Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles Are Internalized in Human Host Cells and Trigger NOD1- and NOD2-Dependent NF-κB Activation

(2014) Bernard Thay et al.   INFECTION AND IMMUNITY

Membrane vesicles of Clostridium perfringens type A strains induce innate and adaptive immunity

(2014) Yanlong Jiang et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Peptidyl Arginine Deiminase fromPorphyromonas gingivalisAbolishes Anaphylatoxin C5a Activity

(2014) Ewa Bielecka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diversion of the host humoral response: a novel virulence mechanism of Haemophilus influenzae mediated via outer membrane vesicles

(2014) Florence Deknuydt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae

(2014) Alfonso Olaya-Abril et al.   Journal of Proteomics

Mycobacterial Membrane Vesicles Administered Systemically in Mice Induce a Protective Immune Response to Surface Compartments of Mycobacterium tuberculosis

(2014) R. Prados-Rosales et al.   mBio

Preferential Packing of Acidic Glycosidases and Proteases into Bacteroides Outer Membrane Vesicles

(2014) W. Elhenawy et al.   mBio

A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut

(2014) Régis Stentz et al.   Cell Reports

Cell-Cell Communication between Malaria-Infected Red Blood Cells via Exosome-like Vesicles

(2013) Neta Regev-Rudzki et al.   CELL

Malaria-Infected Erythrocyte-Derived Microvesicles Mediate Cellular Communication within the Parasite Population and with the Host Immune System

(2013) Pierre-Yves Mantel et al.   Cell Host & Microbe

Staphylococcus aureus α-Toxin-Dependent Induction of Host Cell Death by Membrane-Derived Vesicles

(2013) Bernard Thay et al.   PLoS One

Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions

(2013) Olivia Twu et al.   PLoS Pathogens

Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection

(2012) Yue Shen et al.   Cell Host & Microbe

Campylobacter jejuni Outer Membrane Vesicles Play an Important Role in Bacterial Interactions with Human Intestinal Epithelial Cells

(2012) Abdi Elmi et al.   INFECTION AND IMMUNITY

Biogenesis of Outer Membrane Vesicles in Serratia marcescens Is Thermoregulated and Can Be Induced by Activation of the Rcs Phosphorelay System

(2012) K. J. McMahon et al.   JOURNAL OF BACTERIOLOGY

Microparticles from Mycobacteria-Infected Macrophages Promote Inflammation and Cellular Migration

(2012) S. B. Walters et al.   JOURNAL OF IMMUNOLOGY

Acinetobacter baumannii outer membrane protein a modulates the biogenesis of outer membrane vesicles

(2012) Dong Chan Moon et al.   JOURNAL OF MICROBIOLOGY

NOD-Like Receptor Activation by Outer Membrane Vesicles fromVibrio choleraeNon-O1 Non-O139 Strains Is Modulated by the Quorum-Sensing Regulator HapR

(2011) H. Bielig et al.   INFECTION AND IMMUNITY

Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion

(2010) N. Rolhion et al.   GUT

Selective Sorting of Cargo Proteins into Bacterial Membrane Vesicles

(2010) M. Florencia Haurat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

B Cell Activation by Outer Membrane Vesicles—A Novel Virulence Mechanism

(2010) Maria Laura A. Perez Vidakovics et al.   PLoS Pathogens

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

(2009) Maria Kaparakis et al.   CELLULAR MICROBIOLOGY

Porphyromonas gingivalis Outer Membrane Vesicles Enter Human Epithelial Cells via an Endocytic Pathway and Are Sorted to Lysosomal Compartments

(2009) N. Furuta et al.   INFECTION AND IMMUNITY

Long-Distance Delivery of Bacterial Virulence Factors by Pseudomonas aeruginosa Outer Membrane Vesicles

(2009) Jennifer M. Bomberger et al.   PLoS Pathogens