Outer membrane vesicles displaying engineered glycotopes elicit protective antibodies

Successful Protection against Tularemia in C57BL/6 Mice Is Correlated with Expansion of Francisella tularensis-Specific Effector T Cells

(2014) Amanda J. Griffin et al.   Clinical and Vaccine Immunology

Microbial biosynthesis of designer outer membrane vesicles

(2014) Jenny L Baker et al.   CURRENT OPINION IN BIOTECHNOLOGY

Francisella tularensis Schu S4 Lipopolysaccharide Core Sugar and O-Antigen Mutants Are Attenuated in a Mouse Model of Tularemia

(2014) Jed A. Rasmussen et al.   INFECTION AND IMMUNITY

Mechanistic Insight into the TH1-Biased Immune Response to Recombinant Subunit Vaccines Delivered by Probiotic Bacteria-Derived Outer Membrane Vesicles

(2014) Joseph A. Rosenthal et al.   PLoS One

Innate B cell helpers reveal novel types of antibody responses

(2013) Carola G Vinuesa et al.   NATURE IMMUNOLOGY

Modulating the innate immune response by combinatorial engineering of endotoxin

(2013) Brittany D. Needham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis

(2013) J. Cuccui et al.   Open Biology

Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia

(2012) Zhaohua Lu et al.   IMMUNOLOGY

Recent developments in bacterial protein glycan coupling technology and glycoconjugate vaccine design

(2012) V. S. Terra et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Evaluation of the establishment of herd immunity in the population by means of serological surveys and vaccination coverage

(2012) Pedro Plans-Rubió   Human Vaccines & Immunotherapeutics

Adjuvant properties of meningococcal outer membrane vesicles and the use of adjuvants inNeisseria meningitidisprotein vaccines

(2011) Holly Sanders et al.   Expert Review of Vaccines

Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy-acyltransferase and its role in innate immune recognition

(2011) Jessica V. Hankins et al.   MOLECULAR MICROBIOLOGY

Characterization of bacteria using its O-antigen with surface-enhanced Raman scattering

(2010) I. O. Osorio-Román et al.   ANALYST

Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles

(2010) Adam Kulp et al.   Annual Review of Microbiology

Production of Secretory and Extracellular N-Linked Glycoproteins inEscherichia coli

(2010) Adam C. Fisher et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Immunization withSalmonella entericaSerovar Typhimurium-Derived Outer Membrane Vesicles Delivering the Pneumococcal Protein PspA Confers Protection against Challenge withStreptococcus pneumoniae

(2010) Maneesha Muralinath et al.   INFECTION AND IMMUNITY

Naturally Produced Outer Membrane Vesicles from Pseudomonas aeruginosa Elicit a Potent Innate Immune Response via Combined Sensing of Both Lipopolysaccharide and Protein Components

(2010) T. N. Ellis et al.   INFECTION AND IMMUNITY

Production of glycoprotein vaccines in Escherichia coli

(2010) Julian Ihssen et al.   Microbial Cell Factories

New vaccine platform?

(2010) Alexandra Flemming   NATURE REVIEWS DRUG DISCOVERY

Carbohydrate vaccines: developing sweet solutions to sticky situations?

(2010) Rena D. Astronomo et al.   NATURE REVIEWS DRUG DISCOVERY

Identification, Characterization and Immunogenicity of an O-Antigen Capsular Polysaccharide of Francisella tularensis

(2010) Michael A. Apicella et al.   PLoS One

Delivery of foreign antigens by engineered outer membrane vesicle vaccines

(2010) D. J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Bacterial Carbohydrates Influence the Adaptive Immune System

(2009) Fikri Y. Avci et al.   Annual Review of Immunology

A Novel Role for Plasmin-Mediated Degradation of Opsonizing Antibody in the Evasion of Host Immunity by Virulent, but Not Attenuated, Francisella tularensis

(2009) D. D. Crane et al.   JOURNAL OF IMMUNOLOGY

Working toward the Future: Insights into Francisella tularensis Pathogenesis and Vaccine Development

(2009) R. D. Pechous et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis

(2009) Johan Holst et al.   VACCINE

Preparation of bacterial polysaccharide–protein conjugates: Analytical and manufacturing challenges

(2009) Carl E. Frasch   VACCINE

Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant

(2008) C. R. Casella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Discovery of new biosynthetic pathways: the lipid A story

(2008) Christian R. H. Raetz et al.   JOURNAL OF LIPID RESEARCH

Engineered Bacterial Outer Membrane Vesicles with Enhanced Functionality

(2008) Jae-Young Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

(2008) Caroline L. Trotter et al.   VACCINE