Infection with the Lyme disease pathogen suppresses innate immunity in mice with diet-induced obesity

Hyperglycemia Impairs Neutrophil-Mediated Bacterial Clearance in Mice Infected with the Lyme Disease Pathogen

(2016) Ashkan Javid et al.   PLoS One

Macrophages: Development and Tissue Specialization

(2015) Chen Varol et al.   Annual Review of Immunology

Borrelia burgdorferi Pathogenesis and the Immune Response

(2015) Mary Petzke et al.   CLINICS IN LABORATORY MEDICINE

Epidermal Fatty Acid Binding Protein Promotes Skin Inflammation Induced by High-Fat Diet

(2015) Yuwen Zhang et al.   IMMUNITY

A Humoral Immune Defect Distinguishes the Response to Staphylococcus aureus Infections in Mice with Obesity and Type 2 Diabetes from That in Mice with Type 1 Diabetes

(2015) Christopher W. Farnsworth et al.   INFECTION AND IMMUNITY

Epidemiology of Lyme Disease

(2015) Paul S. Mead   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Differences in Hematopoietic Stem Cells Contribute to Sexually Dimorphic Inflammatory Responses to High Fat Diet-induced Obesity

(2015) Kanakadurga Singer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of obesity and infections

(2015) N. V. Dhurandhar et al.   Obesity Reviews

Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-feverBorrelia

(2015) Alvaro Toledo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The gut microbiota in human energy homeostasis and obesity

(2015) Michael Rosenbaum et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection

(2015) Rebecca A. Elsner et al.   PLoS Pathogens

Differential regulation of pancreatic digestive enzymes during chronic high-fat diet-induced obesity in C57BL/6J mice

(2014) Ruth Z. Birk et al.   BRITISH JOURNAL OF NUTRITION

Fractalkine (CX3CL1) Is Involved in the Early Activation of Hypothalamic Inflammation in Experimental Obesity

(2014) Joseane Morari et al.   DIABETES

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Neutrophils at work

(2014) William M Nauseef et al.   NATURE IMMUNOLOGY

Resurgence of Persisting Non-Cultivable Borrelia burgdorferi following Antibiotic Treatment in Mice

(2014) Emir Hodzic et al.   PLoS One

Mechanisms of Borrelia burgdorferi internalization and intracellular innate immune signaling

(2014) Tanja Petnicki-Ocwieja et al.   Frontiers in Cellular and Infection Microbiology

Phagosomal TLR signaling upon Borrelia burgdorferi infection

(2014)   Frontiers in Cellular and Infection Microbiology

Innate Immune Receptors: Key Regulators of Metabolic Disease Progression

(2013) Chengcheng Jin et al.   Cell Metabolism

Microbes and obesity—interrelationship between infection, adipose tissue and the immune system

(2013) V. Hegde et al.   CLINICAL MICROBIOLOGY AND INFECTION

CD14 Targets Complement Receptor 3 to Lipid Rafts during Phagocytosis of Borrelia burgdorferi

(2013) Kelly L. Hawley et al.   International Journal of Biological Sciences

SeXX matters in immunity

(2013) J.G. Markle et al.   TRENDS IN IMMUNOLOGY

Current insights into neutrophil homeostasis

(2012) Stefanie Bugl et al.   Annals of the New York Academy of Sciences

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

(2012) Lydia Lynch et al.   IMMUNITY

Insulin Treatment Directly Restores Neutrophil Phagocytosis and Bactericidal Activity in Diabetic Mice and Thereby Improves Surgical Site Staphylococcus aureus Infection

(2012) Hidekazu Yano et al.   INFECTION AND IMMUNITY

Spirochete antigens persist near cartilage after murine Lyme borreliosis therapy

(2012) Linda K. Bockenstedt et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage p38 Mitogen-Activated Protein Kinase Activity Regulates Invariant Natural Killer T-Cell Responses During Borrelia burgdorferi Infection

(2012) Kelly Hawley et al.   JOURNAL OF INFECTIOUS DISEASES

Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules

(2012) Tara J. Moriarty et al.   MOLECULAR MICROBIOLOGY

CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi

(2012) K. L. Hawley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD14 Modulates Inflammation-Driven Insulin Resistance

(2011) J. M. Fernandez-Real et al.   DIABETES

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

(2011) Mariel M Finucane et al.   LANCET

Tumor necrosis factor induces GSK3 kinase–mediated cross-tolerance to endotoxin in macrophages

(2011) Sung Ho Park et al.   NATURE IMMUNOLOGY

Sex differences in the clinical and serologic presentation of early lyme disease: Results from a retrospective review

(2010) Alison Schwarzwalder et al.   Gender Medicine

Rodent models of diabetic cardiomyopathy

(2009) H. Bugger et al.   Disease Models & Mechanisms

Local Production of IFN-  by Invariant NKT Cells Modulates Acute Lyme Carditis

(2009) C. M. Olson et al.   JOURNAL OF IMMUNOLOGY

Downstream Signals for MyD88-Mediated Phagocytosis of Borrelia burgdorferi Can Be Initiated by TRIF and Are Dependent on PI3K

(2009) O. S. Shin et al.   JOURNAL OF IMMUNOLOGY

CD14 Signaling Restrains Chronic Inflammation through Induction of p38-MAPK/SOCS-Dependent Tolerance

(2009) Bikash Sahay et al.   PLoS Pathogens

Real-Time High Resolution 3D Imaging of the Lyme Disease Spirochete Adhering to and Escaping from the Vasculature of a Living Host

(2008) Tara J. Moriarty et al.   PLoS Pathogens