Imaging the Perivascular Space as a Potential Biomarker of Neurovascular and Neurodegenerative Diseases

Development and initial evaluation of a semi-automatic approach to assess perivascular spaces on conventional magnetic resonance images

(2016) Xin Wang et al.   JOURNAL OF NEUROSCIENCE METHODS

Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People

(2016) Andrew S.P. Lim et al.   STROKE

Venular degeneration leads to vascular dysfunction in a transgenic model of Alzheimer’s disease

(2015) Aaron Y. Lai et al.   BRAIN

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia

(2015) Aiqing Chen et al.   BRAIN

Cerebral Perivascular Spaces Visible on Magnetic Resonance Imaging: Development of a Qualitative Rating Scale and its Observer Reliability

(2015) Gillian M. Potter et al.   CEREBROVASCULAR DISEASES

Lymphatic vessels of the dura mater: a new discovery?

(2015) Fabio Bucchieri et al.   JOURNAL OF ANATOMY

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Forgotten findings of brain lymphatics

(2015) Éva Mezey et al.   NATURE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

The Glymphatic System: A Beginner’s Guide

(2015) Nadia Aalling Jessen et al.   NEUROCHEMICAL RESEARCH

White Matter Perivascular Spaces on Magnetic Resonance Imaging

(2015) Andreas Charidimou et al.   STROKE

Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease

(2015) Ibrahim González-Marrero et al.   Frontiers in Cellular Neuroscience

COLLAGENOSIS OF THE DEEP MEDULLARY VEINS CORRELATES WITH PERIVENTRICULAR WHITE MATTER CHANGES IN ALZHEIMER'S DISEASE

(2014) Fuqiang Gao et al.   Alzheimers & Dementia

Impairment of paravascular clearance pathways in the aging brain

(2014) Benjamin T. Kress et al.   ANNALS OF NEUROLOGY

White Matter Changes in Dementia: Role of Impaired Drainage of Interstitial Fluid

(2014) Roy O. Weller et al.   BRAIN PATHOLOGY

Failure of Perivascular Drainage of β-amyloid in Cerebral Amyloid Angiopathy

(2014) Cheryl A. Hawkes et al.   BRAIN PATHOLOGY

Amyloid-β diurnal pattern: possible role of sleep in Alzheimer's disease pathogenesis

(2014) Brendan P. Lucey et al.   NEUROBIOLOGY OF AGING

Circulating Inflammatory Markers Are Associated With Magnetic Resonance Imaging-Visible Perivascular Spaces But Not Directly With White Matter Hyperintensities

(2014) Benjamin S. Aribisala et al.   STROKE

Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease

(2013) Sarah M. Rothman et al.   BRAIN RESEARCH

Enlarged Perivascular Spaces and Cerebral Small Vessel Disease

(2013) Gillian M. Potter et al.   International Journal of Stroke

Towards the automatic computational assessment of enlarged perivascular spaces on brain magnetic resonance images: A systematic review

(2013) Maria del C. Valdés Hernández et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study

(2013) A. Charidimou et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain

(2013) J. J. Iliff et al.   JOURNAL OF NEUROSCIENCE

A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric A , and Frank Neuronal Loss

(2013) R. M. Cohen et al.   JOURNAL OF NEUROSCIENCE

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Lymphatic Function and Immune Regulation in Health and Disease

(2013) Shan Liao et al.   Lymphatic Research and Biology

Physiology of the Intrathecal Bolus: The Leptomeningeal Route for Macromolecule and Particle Delivery to CNS

(2013) Mikhail I. Papisov et al.   MOLECULAR PHARMACEUTICS

Topography of dilated perivascular spaces in subjects from a memory clinic cohort

(2013) S. Martinez-Ramirez et al.   NEUROLOGY

White matter perivascular spaces: An MRI marker in pathology-proven cerebral amyloid angiopathy?

(2013) A. Charidimou et al.   NEUROLOGY

Garbage Truck of the Brain

(2013) M. Nedergaard   SCIENCE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Is There a Cerebral Lymphatic System?

(2013) J. J. Iliff et al.   STROKE

Rating Method for Dilated Virchow–Robin Spaces on Magnetic Resonance Imaging

(2013) Hieab H.H. Adams et al.   STROKE

Real-Time In Vivo Imaging Reveals the Ability of Monocytes to Clear Vascular Amyloid Beta

(2013) Jean-Philippe Michaud et al.   Cell Reports

Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease

(2012) Adrienne Dorr et al.   BRAIN

Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele

(2012) Cheryl A. Hawkes et al.   PLoS One

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

Assessment of the Virchow-Robin Spaces in Alzheimer Disease, Mild Cognitive Impairment, and Normal Aging, Using High-Field MR Imaging

(2011) W. Chen et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Frequency and Location of Dilated Virchow-Robin Spaces in Elderly People: A Population-Based 3D MR Imaging Study

(2011) Y.-C. Zhu et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Effects of Age and Amyloid Deposition on Aβ Dynamics in the Human Central Nervous System

(2011) Yafei Huang   ARCHIVES OF NEUROLOGY

Evaluation of Specific Metabolic Rates of Major Organs and Tissues: Comparison Between Nonobese and Obese Women

(2011) ZiMian Wang et al.   Obesity

Sex differences in the inflammatory response of primary astrocytes to lipopolysaccharide

(2011) María Santos-Galindo et al.   Biology of Sex Differences

Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations

(2010) A. A. Gouw et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

(2010) Leonardo Pantoni   LANCET NEUROLOGY

Severity of Dilated Virchow-Robin Spaces Is Associated With Age, Blood Pressure, and MRI Markers of Small Vessel Disease

(2010) Yi-Cheng Zhu et al.   STROKE

Enlarged Perivascular Spaces on MRI Are a Feature of Cerebral Small Vessel Disease

(2010) Fergus N. Doubal et al.   STROKE

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy

(2009) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE

Lymphatic drainage of the brain and the pathophysiology of neurological disease

(2008) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

Perivascular spaces--MRI marker of inflammatory activity in the brain?

(2008) J. Wuerfel et al.   BRAIN

Virchow-Robin spaces relate to cerebral small vessel disease severity

(2008) R. P. W. Rouhl et al.   JOURNAL OF NEUROLOGY

The Lymphatic System in Health and Disease

(2008) Leah N. Cueni et al.   Lymphatic Research and Biology

Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

(2008) R. O. Carare et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease

(2008) E. P. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding White Matter Disease: Imaging-Pathological Correlations in Vascular Cognitive Impairment

(2008) S. Black et al.   STROKE