Inhibition of Autophagy by Chloroquine Enhances the Antitumor Efficacy of Sorafenib in Glioblastoma

Invasive Glioblastoma Cells Acquire Stemness and Increased Akt Activation

(2015) Jennifer R. Molina et al.   NEOPLASIA

Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma

(2014) A F Hottinger et al.   BRITISH JOURNAL OF CANCER

Sorafenib Inhibition of Hepatic Stellate Cell Proliferation in Tumor Microenvironment of Hepatocellular Carcinoma: A Study of the Sorafenib Mechanisms

(2014) Zhi-min Geng et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells

(2014) Dali Zhao et al.   CELLULAR SIGNALLING

Sorafenib Blocks the HIF-1α/VEGFA Pathway, Inhibits Tumor Invasion, and Induces Apoptosis in Hepatoma Cells

(2014) Ming Xu et al.   DNA AND CELL BIOLOGY

Sorafenib/Regorafenib and Lapatinib Interact to kill CNS Tumor Cells

(2014) Hossein A. Hamed et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Raloxifene Induces Autophagy-Dependent Cell Death in Breast Cancer Cells via the Activation of AMP-Activated Protein Kinase

(2014) Dong Eun Kim et al.   MOLECULES AND CELLS

Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas

(2014) M. A. Karajannis et al.   NEURO-ONCOLOGY

New Molecules and Old Drugs as Emerging Approaches to Selectively Target Human Glioblastoma Cancer Stem Cells

(2014) Roberto Würth et al.   Biomed Research International

Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures

(2013) Elisa Carra et al.   CELL CYCLE

Phase II Study of Bevacizumab in Combination with Sorafenib in Recurrent Glioblastoma (N0776): A North Central Cancer Treatment Group Trial

(2013) E. Galanis et al.   CLINICAL CANCER RESEARCH

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

(2013)   NATURE GENETICS

NABTT 0502: a phase II and pharmacokinetic study of erlotinib and sorafenib for patients with progressive or recurrent glioblastoma multiforme

(2013) David M. Peereboom et al.   NEURO-ONCOLOGY

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process

(2012) P Gonzalez et al.   CELL DEATH AND DIFFERENTIATION

Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02

(2012) E. Q. Lee et al.   NEURO-ONCOLOGY

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

(2011) Ying-Hong Shi et al.   Autophagy

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

(2011) Satoshi Shimizu et al.   INTERNATIONAL JOURNAL OF CANCER

Phase I trial of sorafenib in patients with recurrent or progressive malignant glioma

(2011) L. B. Nabors et al.   NEURO-ONCOLOGY

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Sorafenib exerts anti-glioma activity in vitro and in vivo

(2010) Markus D. Siegelin et al.   NEUROSCIENCE LETTERS

Chloroquine in glioblastoma-New horizons for an old drug

(2009) Anusheel Munshi   CANCER

STAT3 Regulation of Glioblastoma Pathogenesis

(2009) Nuria la Iglesia et al.   CURRENT MOLECULAR MEDICINE

Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2

(2009) Boris R. A. Blechacz et al.   HEPATOLOGY

Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas

(2008) F. Yang et al.   MOLECULAR CANCER THERAPEUTICS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE