Cardiomyocyte proliferation in zebrafish and mammals: lessons for human disease

CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart

(2015) G. Matrone et al.   JOURNAL OF CELL SCIENCE

Redox Signaling in Cardiac Renewal

(2014) Wataru Kimura et al.   ANTIOXIDANTS & REDOX SIGNALING

CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes

(2014) Shoji Tane et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

Macro advances in microRNAs and myocardial regeneration

(2014) Jun Wang et al.   CURRENT OPINION IN CARDIOLOGY

The zebrafish as a tool to identify novel therapies for human cardiovascular disease

(2014) A. Asnani et al.   Disease Models & Mechanisms

Influenza A virus infection in zebrafish recapitulates mammalian infection and sensitivity to anti-influenza drug treatment

(2014) Kristin A. Gabor et al.   Disease Models & Mechanisms

Macrophages are required for neonatal heart regeneration

(2014) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation

(2014) Zhiqiang Lin et al.   Stem Cell Research

Targeted Laser Ablation of the Zebrafish Larval Heart Induces Models of Heart Block, Valvular Regurgitation, and Outflow Tract Obstruction

(2014) Gianfranco Matrone et al.   Zebrafish

Is it ever possible to treat left ventricular free wall rupture conservatively?

(2014) Abdul Nasir et al.   Interactive Cardiovascular and Thoracic Surgery

Mammalian Cardiac Regeneration After Fetal Myocardial Infarction Requires Cardiac Progenitor Cell Recruitment

(2013) Myron Allukian et al.   ANNALS OF THORACIC SURGERY

Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function

(2013) B. Guner-Ataman et al.   DEVELOPMENT

In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration

(2013) W.-Y. Choi et al.   DEVELOPMENT

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success

(2013) G. Dragneva et al.   Disease Models & Mechanisms

Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair

(2013) Gianfranco Matrone et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Hyaluronan Enhances Bone Marrow Cell Therapy for Myocardial Repair After Infarction

(2013) Chien-Hsi Chen et al.   MOLECULAR THERAPY

A systematic genome-wide analysis of zebrafish protein-coding gene function

(2013) Ross N. W. Kettleborough et al.   NATURE

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

(2013) Ahmed I. Mahmoud et al.   NATURE

Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration

(2013) Ying Huang et al.   PLoS One

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiomyocyte proliferation contributes to heart growth in young humans

(2013) Mariya Mollova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heart repair: from natural mechanisms of cardiomyocyte production to the design of new cardiac therapies

(2012) Silvia Martin-Puig et al.   Annals of the New York Academy of Sciences

Cardiac Regenerative Capacity and Mechanisms

(2012) Kazu Kikuchi et al.   Annual Review of Cell and Developmental Biology

Uncovering the Molecular and Cellular Mechanisms of Heart Development Using the Zebrafish

(2012) David Staudt et al.   Annual Review of Genetics

Cardiac progenitors derived from reprogrammed mesenchymal stem cells contribute to angiomyogenic repair of the infarcted heart

(2012) Stephanie Buccini et al.   BASIC RESEARCH IN CARDIOLOGY

Evolution and development of the building plan of the vertebrate heart

(2012) Bjarke Jensen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regenerating functional heart tissue for myocardial repair

(2012) Andre Alcon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Heart Disease and Stroke Statistics—2013 Update

(2012) Alan S. Go et al.   CIRCULATION

Zebrafish in the Study of Early Cardiac Development

(2012) Jiandong Liu et al.   CIRCULATION RESEARCH

The regenerative capacity of the zebrafish heart is dependent on TGF  signaling

(2012) F. Chablais et al.   DEVELOPMENT

Cell cycle regulation in mouse heart during embryonic and postnatal stages

(2012) Aiko Ikenishi et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Zebrafish models in cardiac development and congenital heart birth defects

(2012) Shu Tu et al.   DIFFERENTIATION

Functional screening identifies miRNAs inducing cardiac regeneration

(2012) Ana Eulalio et al.   NATURE

Cryoinjury as a myocardial infarction model for the study of cardiac regeneration in the zebrafish

(2012) Juan Manuel González-Rosa et al.   Nature Protocols

Development and Validation of an Automated High-Throughput System for Zebrafish In Vivo Screenings

(2012) Ainhoa Letamendia et al.   PLoS One

Hypoxic Preconditioning Improves Survival of Cardiac Progenitor Cells: Role of Stromal Cell Derived Factor-1α–CXCR4 Axis

(2012) Fengdi Yan et al.   PLoS One

Heart repair and regeneration: Recent insights from zebrafish studies

(2012) Ching-Ling Lien et al.   WOUND REPAIR AND REGENERATION

Zebrafish as a model to study cardiac development and human cardiac disease

(2011) J. Bakkers   CARDIOVASCULAR RESEARCH

Adult Cardiac-Resident MSC-like Stem Cells with a Proepicardial Origin

(2011) James J.H. Chong et al.   Cell Stem Cell

Stem cell therapy for chronic heart failure. Lessons from a 15-year experience

(2011) Philippe Menasché   COMPTES RENDUS BIOLOGIES

Imaged-based High-Throughput Screening for Anti-Angiogenic Drug Discovery

(2011) Lasse Evensen et al.   CURRENT PHARMACEUTICAL DESIGN

Zebrafish cardiac development requires a conserved secondary heart field

(2011) D. Hami et al.   DEVELOPMENT

Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2

(2011) J. A. Guadix et al.   DEVELOPMENT

Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish

(2011) J. R. Becker et al.   Disease Models & Mechanisms

Redox signaling in cardiac myocytes

(2011) Celio X.C. Santos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardiac muscle regeneration: lessons from development

(2011) M. Mercola et al.   GENES & DEVELOPMENT

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Pervasive roles of microRNAs in cardiovascular biology

(2011) Eric M. Small et al.   NATURE

De novo cardiomyocytes from within the activated adult heart after injury

(2011) Nicola Smart et al.   NATURE

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

Regeneration of Cryoinjury Induced Necrotic Heart Lesions in Zebrafish Is Associated with Epicardial Activation and Cardiomyocyte Proliferation

(2011) Kristin Schnabel et al.   PLoS One

PlGF Repairs Myocardial Ischemia through Mechanisms of Angiogenesis, Cardioprotection and Recruitment of Myo-Angiogenic Competent Marrow Progenitors

(2011) Hiroto Iwasaki et al.   PLoS One

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Genetic Origins of Birth Defects Revealed by New Animal Model

(2011) Janelle Weaver   PLOS BIOLOGY

Return to the fetal gene program

(2010) Heinrich Taegtmeyer et al.   Annals of the New York Academy of Sciences

C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

(2010) Pontus Boström et al.   CELL

Cyclin-dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes

(2010) Shinji Kaichi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Improved myocardial performance in infarcted rat heart by co-injection of basic fibroblast growth factor with temperature-responsive Chitosan hydrogel

(2010) Haibin Wang et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes

(2010) Kazu Kikuchi et al.   NATURE

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

Lessons for cardiac regeneration and repair through development

(2010) Jeffrey M. Alexander et al.   TRENDS IN MOLECULAR MEDICINE

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

(2009) Kevin Bersell et al.   CELL

Common genetic control of haemangioblast and cardiac development in zebrafish

(2009) T. Peterkin et al.   DEVELOPMENT

Animal Models of Myocardial and Vascular Injury

(2009) Aaron M. Abarbanell et al.   JOURNAL OF SURGICAL RESEARCH

Analysis of Ventricular Hypertrabeculation and Noncompaction Using Genetically Engineered Mouse Models

(2009) Hanying Chen et al.   PEDIATRIC CARDIOLOGY

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Coadministration of Endothelial and Smooth Muscle Progenitor Cells Enhances the Efficiency of Proangiogenic Cell-Based Therapy

(2008) Philippe Foubert et al.   CIRCULATION RESEARCH

Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number

(2008) Kimara L. Targoff et al.   DEVELOPMENTAL BIOLOGY

ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration

(2008) Agustin Rojas-Muñoz et al.   DEVELOPMENTAL BIOLOGY

Compensatory Growth of Healthy Cardiac Cells in the Presence of Diseased Cells Restores Tissue Homeostasis during Heart Development

(2008) Jörg-Detlef Drenckhahn et al.   DEVELOPMENTAL CELL

A Jumonji (Jarid2) Protein Complex Repressescyclin D1Expression by Methylation of Histone H3-K9

(2008) Haruki Shirato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY