NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness
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Title
NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness
Authors
Keywords
Dynein, Microtubules, Neurodevelopment, Neuron differentiation, Oligopeptidase activity, Schizophrenia
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 74, Issue 7, Pages 1191-1210
Publisher
Springer Nature
Online
2016-10-14
DOI
10.1007/s00018-016-2395-7
References
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Note: Only part of the references are listed.- NDE1 and GSK3β Associate with TRAK1 and Regulate Axonal Mitochondrial Motility: Identification of Cyclic AMP as a Novel Modulator of Axonal Mitochondrial Trafficking
- (2016) Fumiaki Ogawa et al. ACS Chemical Neuroscience
- Overlapping 16p13.11 deletion and gain of copies variations associated with childhood onset psychosis include genes with mechanistic implications for autism associated pathways: Two case reports
- (2016) Catherine A. Brownstein et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Inflammatory mediator bradykinin increases population of sensory neurons expressing functional T-type Ca2+ channels
- (2016) Dongyang Huang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Developmental Alcohol Exposure Impairs Activity-DependentS-Nitrosylation of NDEL1 for Neuronal Maturation
- (2016) Atsushi Saito et al. CEREBRAL CORTEX
- CPAP promotes timely cilium disassembly to maintain neural progenitor pool
- (2016) Elke Gabriel et al. EMBO JOURNAL
- Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway
- (2016) Hironori Inaba et al. JOURNAL OF CELL BIOLOGY
- Ndel1 and Reelin Maintain Postnatal CA1 Hippocampus Integrity
- (2016) Yulan Jiang et al. JOURNAL OF NEUROSCIENCE
- Cloning of the promoter of NDE1, a gene implicated in psychiatric and neurodevelopmental disorders through copy number variation
- (2016) N.J. Bradshaw NEUROSCIENCE
- Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain
- (2016) Yun-Sik Choi et al. NEUROSCIENCE
- Genome-wide investigation of schizophrenia associated plasma Ndel1 enzyme activity
- (2016) Ary Gadelha et al. SCHIZOPHRENIA RESEARCH
- A maternally inherited 16p13.11-p12.3 duplication concomitant with a de novoSOX5deletion in a male patient with global developmental delay, disruptive and obsessive behaviors and minor dysmorphic features
- (2015) Ines Quintela et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Mechanism and Regulation of Cytoplasmic Dynein
- (2015) Michael A. Cianfrocco et al. Annual Review of Cell and Developmental Biology
- Protein-Protein and Peptide-Protein Interactions of NudE-Like 1 (Ndel1): A Protein Involved in Schizophrenia
- (2015) M.A.F. Hayashi et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length
- (2015) D. Maskey et al. EMBO JOURNAL
- Increased expression of NDEL1 and MBP genes in the peripheral blood of antipsychotic-naïve patients with first-episode psychosis
- (2015) Vanessa Kiyomi Ota et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- DBZ Regulates Cortical Cell Positioning and Neurite Development by Sustaining the Anterograde Transport of Lis1 and DISC1 through Control of Ndel1 Dual-Phosphorylation
- (2015) M. Okamoto et al. JOURNAL OF NEUROSCIENCE
- An interaction between NDE1 and high birth weight increases schizophrenia susceptibility
- (2015) Asko Wegelius et al. PSYCHIATRY RESEARCH
- GSK-3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility
- (2015) Feng J. Gao et al. TRAFFIC
- A CGH array study in nonsyndromic (primary) autism patients: deletions on16p13.11, 16p11.2, 1q21.1, 2q21.1q21.2, and 8p23.1
- (2015) Kudret Esen GÜMÜŞLÜ et al. Turkish Journal Of Medical Sciences
- Lis1 restricts the conformational changes in cytoplasmic dynein on microtubules
- (2015) Shiori Toba et al. Microscopy
- Neurotensin-Like Peptides as Potential Antipsychotics: Modulation of the Serotonin System
- (2014) N. V. Kost et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- The current view for the silencing of the spindle assembly checkpoint
- (2014) Yanchang Wang et al. CELL CYCLE
- Switching on sex: transcriptional regulation of the testis-determining gene Sry
- (2014) C. Larney et al. DEVELOPMENT
- SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown
- (2014) Yagmur Turgay et al. JOURNAL OF CELL BIOLOGY
- Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study
- (2014) Lauren M. McGrath et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- The expression and roles of Nde1 and Ndel1 in the adult mammalian central nervous system
- (2014) Z. Pei et al. NEUROSCIENCE
- NDEL1 was decreased in the CA3 region but increased in the hippocampal blood vessel network during the spontaneous seizure period after pilocarpine-induced status epilepticus
- (2014) Q. Wu et al. NEUROSCIENCE
- Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility
- (2014) Hiroki Kimura et al. SCHIZOPHRENIA BULLETIN
- Lis1 regulates dynein by sterically blocking its mechanochemical cycle
- (2014) Katerina Toropova et al. eLife
- The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation
- (2014) Shauna L Houlihan et al. eLife
- p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex
- (2014) C. Belzil et al. Biology Open
- Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation
- (2014) T Kuga et al. Oncogenesis
- Deletion 16p13.11 uncoversNDE1mutations on the non-deleted homolog and extends the spectrum of severe microcephaly to include fetal brain disruption
- (2013) Alex R. Paciorkowski et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Analysis of copy number variations at 15 schizophrenia-associated loci
- (2013) Elliott Rees et al. BRITISH JOURNAL OF PSYCHIATRY
- Tissue kallikrein mediates neurite outgrowth through epidermal growth factor receptor and flotillin-2 pathway in vitro
- (2013) Zhengyu Lu et al. CELLULAR SIGNALLING
- Iterative phenotyping of 15q11.2, 15q13.3 and 16p13.11 microdeletion carriers in pediatric epilepsies
- (2013) Johanna A. Jähn et al. EPILEPSY RESEARCH
- Identification of altered dipeptidyl-peptidase activities as potential biomarkers for unipolar depression
- (2013) Jingti Deng et al. JOURNAL OF AFFECTIVE DISORDERS
- Big steps toward understanding dynein
- (2013) Masahide Kikkawa JOURNAL OF CELL BIOLOGY
- Systematic dissection of dynein regulators in mitosis
- (2013) Jonne A. Raaijmakers et al. JOURNAL OF CELL BIOLOGY
- Cortical Murine Neurons Lacking the Neurofilament Light Chain Protein Have an Attenuated Response to Injury In Vitro
- (2013) Catherine A. Blizzard et al. JOURNAL OF NEUROTRAUMA
- Plasma Ndel1 enzyme activity is reduced in patients with schizophrenia – A potential biomarker?
- (2013) Ary Gadelha et al. JOURNAL OF PSYCHIATRIC RESEARCH
- The Phosphatase PP4c Controls Spindle Orientation to Maintain Proliferative Symmetric Divisions in the Developing Neocortex
- (2013) Yunli Xie et al. NEURON
- Male-Biased Autosomal Effect of 16p13.11 Copy Number Variation in Neurodevelopmental Disorders
- (2013) Maria Tropeano et al. PLoS One
- Ohnologs are overrepresented in pathogenic copy number mutations
- (2013) A. McLysaght et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct Functions of Nuclear Distribution Proteins LIS1, Ndel1 and NudCL in Regulating Axonal Mitochondrial Transport
- (2013) Chong-Yu Shao et al. TRAFFIC
- The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity
- (2012) Zoltán Szeltner et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase
- (2012) Karol Kaszuba et al. BIOCHIMIE
- CNVs: Harbingers of a Rare Variant Revolution in Psychiatric Genetics
- (2012) Dheeraj Malhotra et al. CELL
- Lis1 Acts as a “Clutch” between the ATPase and Microtubule-Binding Domains of the Dynein Motor
- (2012) Julie Huang et al. CELL
- Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions
- (2012) Shuang Wu et al. CELL RESEARCH
- Misfolded Gβ is recruited to cytoplasmic dynein by Nudel for efficient clearance
- (2012) Yihan Wan et al. CELL RESEARCH
- Intrinsic Disorder in Dynein Intermediate Chain Modulates Its Interactions with NudE and Dynactin
- (2012) Afua Nyarko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Mitosis and Neurodevelopment Proteins NDE1 and NDEL1 Form Dimers, Tetramers, and Polymers with a Folded Back Structure in Solution
- (2012) Dinesh C. Soares et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The human testis-determining factor SRY localizes in midbrain dopamine neurons and regulates multiple components of catecholamine synthesis and metabolism
- (2012) Daniel P. Czech et al. JOURNAL OF NEUROCHEMISTRY
- Activation of Aurora-A Is Essential for Neuronal Migration via Modulation of Microtubule Organization
- (2012) T. Takitoh et al. JOURNAL OF NEUROSCIENCE
- Novel NDE1 homozygous mutation resulting in microhydranencephaly and not microlyssencephaly
- (2012) Ayse Guven et al. NEUROGENETICS
- The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB
- (2012) Eric R Kandel Molecular Brain
- Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon
- (2012) M. Segal et al. Biology Open
- The Essential Role of Centrosomal NDE1 in Human Cerebral Cortex Neurogenesis
- (2011) Mehmet Bakircioglu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Human Mutations in NDE1 Cause Extreme Microcephaly with Lissencephaly
- (2011) Fowzan S. Alkuraya et al. AMERICAN JOURNAL OF HUMAN GENETICS
- De Novo Rates and Selection of Schizophrenia-Associated Copy Number Variants
- (2011) Elliott Rees et al. BIOLOGICAL PSYCHIATRY
- Prolyl Oligopeptidase: A Rising Star on the Stage of Neuroinflammation Research
- (2011) Anne Penttinen et al. CNS & Neurological Disorders-Drug Targets
- Copy number variants of schizophrenia susceptibility loci are associated with a spectrum of speech and developmental delays and behavior problems
- (2011) Trilochan Sahoo et al. GENETICS IN MEDICINE
- Molecular Characterization of Disrupted in Schizophrenia-1 Risk Variant S704C Reveals the Formation of Altered Oligomeric Assembly
- (2011) Saravanakumar Narayanan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutually Exclusive Cytoplasmic Dynein Regulation by NudE-Lis1 and Dynactin
- (2011) Richard J. McKenney et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein
- (2011) Eliza Żyłkiewicz et al. JOURNAL OF CELL BIOLOGY
- A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase
- (2011) Stéphanie Bolhy et al. JOURNAL OF CELL BIOLOGY
- MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells
- (2011) Atsuhiro Tanabe et al. JOURNAL OF CELLULAR PHYSIOLOGY
- 16p13.11 duplication is a risk factor for a wide spectrum of neuropsychiatric disorders
- (2011) Arivudainambi Ramalingam et al. JOURNAL OF HUMAN GENETICS
- PKA Phosphorylation of NDE1 Is DISC1/PDE4 Dependent and Modulates Its Interaction with LIS1 and NDEL1
- (2011) N. J. Bradshaw et al. JOURNAL OF NEUROSCIENCE
- A Cdk5-Dependent Switch Regulates Lis1/Ndel1/Dynein-Driven Organelle Transport in Adult Axons
- (2011) J. P. Pandey et al. JOURNAL OF NEUROSCIENCE
- Genome-wide association analysis of copy number variation in recurrent depressive disorder
- (2011) J J H Rucker et al. MOLECULAR PSYCHIATRY
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry
- (2011) Sehyun Kim et al. NATURE CELL BIOLOGY
- A copy number variation morbidity map of developmental delay
- (2011) Gregory M Cooper et al. NATURE GENETICS
- Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia
- (2011) Detelina Grozeva et al. SCHIZOPHRENIA RESEARCH
- Three-Dimensional Regulation of Radial Glial Functions by Lis1-Nde1 and Dystrophin Glycoprotein Complexes
- (2011) Ashley S. Pawlisz et al. PLOS BIOLOGY
- Rare Deletions at 16p13.11 Predispose to a Diverse Spectrum of Sporadic Epilepsy Syndromes
- (2010) Erin L. Heinzen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- LIS1 and NudE Induce a Persistent Dynein Force-Producing State
- (2010) Richard J. McKenney et al. CELL
- Phenotypic manifestations of copy number variation in chromosome 16p13.11
- (2010) Sandesh C Sreenath Nagamani et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging
- (2010) Kristin K. Nicodemus et al. HUMAN GENETICS
- Functional Dissection of LIS1 and NDEL1 Towards Understanding the Molecular Mechanisms of Cytoplasmic Dynein Regulation
- (2010) Takayuki Torisawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a Novel Dynein Binding Domain in Nudel Essential for Spindle Pole Organization inXenopusEgg Extract
- (2010) Shusheng Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning
- (2010) C. Lam et al. JOURNAL OF CELL SCIENCE
- Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis
- (2010) Nigel M Williams et al. LANCET
- Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth
- (2010) Mirian A.F. Hayashi et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Genetic Mosaic Dissection of Lis1 and Ndel1 in Neuronal Migration
- (2010) Simon Hippenmeyer et al. NEURON
- New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0
- (2010) Stéphane Guindon et al. SYSTEMATIC BIOLOGY
- Long-Term Culture of Mouse Embryonic Stem Cell-Derived Adherent Neurospheres and Functional Neurons
- (2010) Mirian A.F. Hayashi et al. TISSUE ENGINEERING PART C-METHODS
- Genome-Wide Copy Number Variation in Epilepsy: Novel Susceptibility Loci in Idiopathic Generalized and Focal Epilepsies
- (2010) Heather C. Mefford et al. PLoS Genetics
- Association Between Genes of Disrupted in Schizophrenia 1 (DISC1) Interactors and Schizophrenia Supports the Role of the DISC1 Pathway in the Etiology of Major Mental Illnesses
- (2009) Liisa Tomppo et al. BIOLOGICAL PSYCHIATRY
- Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies
- (2009) C. G. F. de Kovel et al. BRAIN
- Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity
- (2009) Anat Shmueli et al. EMBO JOURNAL
- A method for rapid, targeted CNV genotyping identifies rare variants associated with neurocognitive disease
- (2009) H. C. Mefford et al. GENOME RESEARCH
- Opposing effects of Ndel1 and 1 or 2 on cytoplasmic dynein through competitive binding to Lis1
- (2009) C. Ding et al. JOURNAL OF CELL SCIENCE
- Molecular analysis of pericentrin gene (PCNT) in a series of 24 Seckel/microcephalic osteodysplastic primordial dwarfism type II (MOPD II) families
- (2009) M. Willems et al. JOURNAL OF MEDICAL GENETICS
- Distinct Dose-Dependent Cortical Neuronal Migration and Neurite Extension Defects in Lis1 and Ndel1 Mutant Mice
- (2009) Y. H. Youn et al. JOURNAL OF NEUROSCIENCE
- Copy number variations of chromosome 16p13.1 region associated with schizophrenia
- (2009) A Ingason et al. MOLECULAR PSYCHIATRY
- An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics
- (2009) Daisuke Mori et al. NATURE CELL BIOLOGY
- Requirement for Nudel and dynein for assembly of the lamin B spindle matrix
- (2009) Li Ma et al. NATURE CELL BIOLOGY
- The DISC1 Pathway Modulates Expression of Neurodevelopmental, Synaptogenic and Sensory Perception Genes
- (2009) William Hennah et al. PLoS One
- Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport
- (2009) Qiangge Zhang et al. TRAFFIC
- Nudel and FAK as Antagonizing Strength Modulators of Nascent Adhesions through Paxillin
- (2009) Yongli Shan et al. PLOS BIOLOGY
- A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia
- (2009) Anna C. Need et al. PLoS Genetics
- DISC1, PDE4B, and NDE1 at the centrosome and synapse
- (2008) Nicholas J. Bradshaw et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division
- (2008) Jessica Yingling et al. CELL
- Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA)
- (2008) Daniel M. Collins et al. CELLULAR SIGNALLING
- Nudel Binds Cdc42GAP to Modulate Cdc42 Activity at the Leading Edge of Migrating Cells
- (2008) Yidong Shen et al. DEVELOPMENTAL CELL
- LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein
- (2008) Masami Yamada et al. EMBO JOURNAL
- Lis1–Nde1-dependent neuronal fate control determines cerebral cortical size and lamination
- (2008) Ashley S. Pawlisz et al. HUMAN MOLECULAR GENETICS
- Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding
- (2008) K. E. Burdick et al. HUMAN MOLECULAR GENETICS
- Ndel1 Controls the Dynein-mediated Transport of Vimentin during Neurite Outgrowth
- (2008) Su Yeon Shim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
- (2008) Sachin Hebbar et al. JOURNAL OF CELL BIOLOGY
- Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation
- (2008) Kazuhito Toyo-oka et al. JOURNAL OF CELL BIOLOGY
- Recurrent reciprocal deletions and duplications of 16p13.11: the deletion is a risk factor for MR/MCA while the duplication may be a rare benign variant
- (2008) F D Hannes et al. JOURNAL OF MEDICAL GENETICS
- Dynein Light Intermediate Chain: An Essential Subunit That Contributes to Spindle Checkpoint Inactivation
- (2008) Sarah Mische et al. MOLECULAR BIOLOGY OF THE CELL
- NDE1 and NDEL1: Multimerisation, alternate splicing and DISC1 interaction
- (2008) Nicholas J. Bradshaw et al. NEUROSCIENCE LETTERS
- Ndel1 Promotes Axon Regeneration via Intermediate Filaments
- (2008) Cory Toth et al. PLoS One
- Mutations in the Pericentrin (PCNT) Gene Cause Primordial Dwarfism
- (2008) A. Rauch et al. SCIENCE
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