Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology

Immunogen design for HIV-1 and influenza

(2014) Ujjwal Rathore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Encapsulation of adenovirus serotype 5 in anionic lecithin liposomes using a bead-based immunoprecipitation technique enhances transfection efficiency

(2014) Natalie Mendez et al.   BIOMATERIALS

MLV based viral-like-particles for delivery of toxic proteins and nuclear transcription factors

(2014) Dai-Tze Wu et al.   BIOMATERIALS

Generation and characterization of a new mammalian cell line continuously expressing virus-like particles of Japanese encephalitis virus for a subunit vaccine candidate

(2014) Rong-Hong Hua et al.   BMC BIOTECHNOLOGY

Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens

(2014) Neil C. Sheppard et al.   INTERNATIONAL IMMUNOLOGY

Efficient in vitro gene delivery by hybrid biopolymer/virus nanobiovectors

(2014) Rahul Keswani et al.   JOURNAL OF CONTROLLED RELEASE

Thirty years of baculovirus-insect cell protein expression: from dark horse to mainstream technology

(2014) M. M. van Oers et al.   JOURNAL OF GENERAL VIROLOGY

Relative Efficacy of AS03-Adjuvanted Pandemic Influenza A(H1N1) Vaccine in Children: Results of a Controlled, Randomized Efficacy Trial

(2014) Terry Nolan et al.   JOURNAL OF INFECTIOUS DISEASES

Adenoviral targeting using genetically incorporated camelid single variable domains

(2014) Sergey A Kaliberov et al.   LABORATORY INVESTIGATION

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2

(2014) Abdul Ghafoor Khan et al.   NATURE

Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells

(2014) Ana F. Rodrigues et al.   TRENDS IN BIOTECHNOLOGY

Rabies virus-like particles expressed in HEK293 cells

(2014) Diego Fontana et al.   VACCINE

Improved characteristics and protective efficacy in an animal model of E. coli-derived recombinant double-layered rotavirus virus-like particles

(2014) Tingdong Li et al.   VACCINE

Model based estimates of long-term persistence of inactivated hepatitis A vaccine-induced antibodies in adults

(2014) Niel Hens et al.   VACCINE

Rabies virus glycoprotein and immune response pattern using recombinant protein or recombinant RNA viral vectors

(2014) Renato M. Astray et al.   VACCINE

Protection and Antibody Response Caused by Turkey Herpesvirus Vector Newcastle Disease Vaccine

(2013) Motoyuki Esaki et al.   AVIAN DISEASES

Chimeric Derivatives of Hepatitis B Virus Core Particles Carrying Major Epitopes of the Rubella Virus E1 Glycoprotein

(2013) Dace Skrastina et al.   Clinical and Vaccine Immunology

Recombinant Trivalent Influenza Vaccine (Flublok®): A Review of Its Use in the Prevention of Seasonal Influenza in Adults

(2013) Lily P. H. Yang   DRUGS

Virus-like particle-based vaccines against hepatitis C virus infection

(2013) Bertrand Bellier et al.   Expert Review of Vaccines

Efficacy of DNA Vaccines Forming E7 Recombinant Retroviral Virus-Like Particles for the Treatment of Human Papillomavirus-Induced Cancers

(2013) Geraldine Lescaille et al.   HUMAN GENE THERAPY

Efficacy of RG1-VLP Vaccination against Infections with Genital and Cutaneous Human Papillomaviruses

(2013) Christina Schellenbacher et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group

(2013) R. J. de Groot et al.   JOURNAL OF VIROLOGY

Designing Tomorrow's Vaccines

(2013) Gary J. Nabel   NEW ENGLAND JOURNAL OF MEDICINE

High Yield Production of Influenza Virus in Madin Darby Canine Kidney (MDCK) Cells with Stable Knockdown of IRF7

(2013) Itsuki Hamamoto et al.   PLoS One

Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

(2013) L. Kong et al.   SCIENCE

Antibodies in HIV-1 Vaccine Development and Therapy

(2013) F. Klein et al.   SCIENCE

The prospects and challenges of universal vaccines for influenza

(2013) Kanta Subbarao et al.   TRENDS IN MICROBIOLOGY

Self-adjuvanting modular virus-like particles for mucosal vaccination against group A streptococcus (GAS)

(2013) Tania Rivera-Hernandez et al.   VACCINE

Establishment of cell lines with increased susceptibility to EV71/CA16 by stable overexpression of SCARB2

(2013) Xiaojun Li et al.   Virology Journal

A novel platform for virus-like particle-display of flaviviral envelope domain III: induction of Dengue and West Nile virus neutralizing antibodies

(2013) Anthony JS Chua et al.   Virology Journal

Analytical technologies for influenza virus-like particle candidate vaccines: challenges and emerging approaches

(2013) Christine M Thompson et al.   Virology Journal

Assembly and immunological properties of a bivalent virus-like particle (VLP) for avian influenza and Newcastle disease

(2013) Huifang Shen et al.   VIRUS RESEARCH

Antibody Quality and Protection from Lethal Ebola Virus Challenge in Nonhuman Primates Immunized with Rabies Virus Based Bivalent Vaccine

(2013) Joseph E. Blaney et al.   PLoS Pathogens

CAP, a new human suspension cell line for influenza virus production

(2012) Yvonne Genzel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Flipase-mediated cassette exchange inSf9insect cells for stable gene expression

(2012) Fabiana Fernandes et al.   BIOTECHNOLOGY AND BIOENGINEERING

Can an immune-regulatory vaccine prevent HIV infection?

(2012) Tobias Boettler et al.   Expert Review of Anti-Infective Therapy

Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells

(2012) C Goyvaerts et al.   GENE THERAPY

Virus-like particles and α-galactosylceramide form a self-adjuvanting composite particle that elicits anti-tumor responses

(2012) Sara J. McKee et al.   JOURNAL OF CONTROLLED RELEASE

Characterization of Humoral and Cellular Immune Responses Elicited by a Recombinant Adenovirus Serotype 26 HIV-1 Env Vaccine in Healthy Adults (IPCAVD 001)

(2012) Dan H. Barouch et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of cross-protective vaccines on epidemiological and evolutionary dynamics of influenza

(2012) N. Arinaminpathy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant protein vaccines produced in insect cells

(2012) Manon M.J. Cox   VACCINE

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

Production and immunogenicity of chimeric virus-like particles containing porcine reproductive and respiratory syndrome virus GP5 protein

(2012) Wei Wang et al.   VACCINE

Chimeric hepatitis E virus-like particle as a carrier for oral-delivery

(2012) Pitchanee Jariyapong et al.   VACCINE

Recombinant retrovirus-derived virus-like particle-based vaccines induce hepatitis C virus-specific cellular and neutralizing immune responses in mice

(2012) Christophe Huret et al.   VACCINE

The role of vaccination in rabies prevention

(2012) Deborah J Briggs   Current Opinion in Virology

Glycated AAV Vectors: Chemical Redirection of Viral Tissue Tropism

(2011) Eric D. Horowitz et al.   BIOCONJUGATE CHEMISTRY

Self-Assembled Virus-Like Particles from Rotavirus Structural Protein VP6 for Targeted Drug Delivery

(2011) Qinghuan Zhao et al.   BIOCONJUGATE CHEMISTRY

Down-regulation of CD81 tetraspanin in human cells producing retroviral-based particles: Tailoring vector composition

(2011) A.F. Rodrigues et al.   BIOTECHNOLOGY AND BIOENGINEERING

Projecting the effectiveness of RotaTeq® against rotavirus-related hospitalizations and deaths in six Asian countries

(2011) Antoine El Khoury et al.   Human vaccines & immunotherapeutics

Cell selective targeting of a simian virus 40 virus-like particle conjugated to epidermal growth factor

(2011) Yuichi Kitai et al.   JOURNAL OF BIOTECHNOLOGY

A Prime-Boost Strategy Using Virus-Like Particles Pseudotyped for HCV Proteins Triggers Broadly Neutralizing Antibodies in Macaques

(2011) P. Garrone et al.   Science Translational Medicine

Inactivated polio vaccine development for technology transfer using attenuated Sabin poliovirus strains to shift from Salk-IPV to Sabin-IPV

(2011) Wilfried A.M. Bakker et al.   VACCINE

MDCK cell line with inducible allele B NS1 expression propagates delNS1 influenza virus to high titres

(2011) R. van Wielink et al.   VACCINE

HIV-Gag VLPs presenting trimeric HIV-1 gp140 spikes constitutively expressed in stable double transfected insect cell line

(2011) M. Tagliamonte et al.   VACCINE

Generation of HIV-1 Virus-Like Particles expressing different HIV-1 glycoproteins

(2011) M.L. Visciano et al.   VACCINE

The development of recombinant subunit envelope-based vaccines to protect against dengue virus induced disease

(2011) Beth-Ann G. Coller et al.   VACCINE

From research to phase III: Preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine

(2011) Bruno Guy et al.   VACCINE

Engineering of baculovirus vectors for the manufacture of virion-free biopharmaceuticals

(2010) Martin Marek et al.   BIOTECHNOLOGY AND BIOENGINEERING

Production of Retroviral Vectors: Review

(2010) Ana S. Coroadinha et al.   CURRENT GENE THERAPY

Cross-protective immunity to influenza A viruses

(2010) Suzanne L Epstein et al.   Expert Review of Vaccines

DNA vaccines: an historical perspective and view to the future

(2010) Margaret A. Liu   IMMUNOLOGICAL REVIEWS

Rational Design of Immunostimulatory siRNAs

(2010) Michael P Gantier et al.   MOLECULAR THERAPY

Intranasal Immunization with Influenza VLPs Incorporating Membrane-Anchored Flagellin Induces Strong Heterosubtypic Protection

(2010) Bao-Zhong Wang et al.   PLoS One

Multiple tandem copies of conserved gp41 epitopes incorporated in gag virus-like particles elicit systemic and mucosal antibodies in an optimized heterologous vector delivery regimen

(2010) Sumiti Jain et al.   VACCINE

Adenoviral Producer Cells

(2010) Imre Kovesdi et al.   Viruses-Basel

Novel adenovirus vector-based vaccines for HIV-1

(2010) Dan H Barouch   Current Opinion in HIV and AIDS

Prevalence of cross-reactive HIV-1-neutralizing activity in HIV-1-infected patients with rapid or slow disease progression

(2009) Marit J van Gils et al.   AIDS

FluBlok, a next generation influenza vaccine manufactured in insect cells

(2009) Manon M.J. Cox et al.   BIOLOGICALS

Trivalent MDCK cell culture-derived influenza vaccine Optaflu®(Novartis Vaccines)

(2009) Alexander Doroshenko et al.   Expert Review of Vaccines

Influenza and vaccine development: a continued battle

(2009) Karl G Nicholson   Expert Review of Vaccines

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production

(2009) C. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suitability of PER.C6® cells to generate epidemic and pandemic influenza vaccine strains by reverse genetics

(2009) W. Koudstaal et al.   VACCINE

DNA vaccines expressing retrovirus-like particles are efficient immunogens to induce neutralizing antibodies

(2009) Bertrand Bellier et al.   VACCINE

Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers

(2009) David I. Bernstein et al.   VACCINE

ACAM2000: a newly licensed cell culture-based live vaccinia smallpox vaccine

(2008) Richard N Greenberg et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Definition of a Conserved Immunodominant Domain on Hepatitis C Virus E2 Glycoprotein by Neutralizing Human Monoclonal Antibodies

(2008) Z.-Y. Keck et al.   JOURNAL OF VIROLOGY

An avian cell line designed for production of highly attenuated viruses

(2008) Ingo Jordan et al.   VACCINE