Pattern recognition receptors in zebrafish provide functional and evolutionary insight into innate immune signaling pathways

Structure and evolutionary history of a large family of NLR proteins in the zebrafish

(2016) Kerstin Howe et al.   Open Biology

Common and specific downstream signaling targets controlled by Tlr2 and Tlr5 innate immune signaling in zebrafish

(2015) Shuxin Yang et al.   BMC GENOMICS

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Md1 and Rp105 regulate innate immunity and viral resistance in zebrafish

(2015) Sergio Candel et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A DN-mda5 transgenic zebrafish model demonstrates that Mda5 plays an important role in snakehead rhabdovirus resistance

(2015) K.A. Gabor et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Involvement of zebrafish RIG-I in NF-κB and IFN signaling pathways: Insights into functional conservation of RIG-I in antiviral innate immunity

(2015) Li Nie et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7

(2015) Long-Feng Lu et al.   FISH & SHELLFISH IMMUNOLOGY

Abortive Infection of Snakehead Fish Vesiculovirus in ZF4 Cells Was Associated with the RLRs Pathway Activation by Viral Replicative Intermediates

(2015) Wenwen Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

(2015) Umeharu Ohto et al.   NATURE

Embryo engineering study splits scientific community

(2015) J. Kaiser et al.   SCIENCE

The fate of recent duplicated genes following a fourth-round whole genome duplication in a tetraploid fish, common carp (Cyprinus carpio)

(2015) Jiong-Tang Li et al.   Scientific Reports

Understanding the distinguishable structural and functional features in zebrafish TLR3 and TLR22, and their binding modes with fish dsRNA viruses: an exploratory structural model analysis

(2014) Bikash Ranjan Sahoo et al.   AMINO ACIDS

Toll-like receptor recognition of bacteria in fish: Ligand specificity and signal pathways

(2014) Jie Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Zebrafish TRIF, a Golgi-Localized Protein, Participates in IFN Induction and NF- B Activation

(2014) S. Fan et al.   JOURNAL OF IMMUNOLOGY

Teleost TLR22 Recognizes RNA Duplex to Induce IFN and Protect Cells from Birnaviruses

(2014) A. Matsuo et al.   JOURNAL OF IMMUNOLOGY

Inefficient star formation in extremely metal poor galaxies

(2014) Yong Shi et al.   NATURE

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

(2014) Alys Peisley et al.   NATURE

Ligand specificities of Toll-like receptors in fish: Indications from infection studies

(2013) Danilo Pietretti et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Expression profiles of toll-like receptors in channel catfish (Ictalurus punctatus) after infection with Ichthyophthirius multifiliis

(2013) Fei Zhao et al.   FISH & SHELLFISH IMMUNOLOGY

Cell Swelling and the NLRP3 Inflammasome

(2013) Joseph P. Boyle et al.   IMMUNITY

Identification and functional characterization of nonmammalian Toll-like receptor 20

(2013) Danilo Pietretti et al.   IMMUNOGENETICS

Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish

(2013) D.-W. Yeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

(2013) N. Kayagaki et al.   SCIENCE

Diversification of the expanded teleost-specific toll-like receptor family in Atlantic cod, Gadus morhua

(2012) Arvind YM Sundaram et al.   BMC EVOLUTIONARY BIOLOGY

The mammalian PYHIN gene family: Phylogeny, evolution and expression

(2012) Jasmyn A Cridland et al.   BMC EVOLUTIONARY BIOLOGY

Molecular regulation of interferon antiviral response in fish

(2012) Yi-Bing Zhang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

(2012) Tengchuan Jin et al.   IMMUNITY

Roles of Inflammatory Caspases during Processing of Zebrafish Interleukin-1β in Francisella noatunensis Infection

(2012) Lucia N. Vojtech et al.   INFECTION AND IMMUNITY

Structural insights of rohu TLR3, its binding site analysis with fish reovirus dsRNA, poly I:C and zebrafish TRIF

(2012) Bikash R. Sahoo et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Caspase-1 and IL-1β Processing in a Teleost Fish

(2012) Marta I. R. Reis et al.   PLoS One

Teleost fish interferons and their role in immunity

(2011) Jun Zou et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The interleukins of fish

(2011) C.J. Secombes et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish

(2011) S. H. Oehlers et al.   Disease Models & Mechanisms

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7

(2011) F. Sun et al.   JOURNAL OF IMMUNOLOGY

Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)

(2011) M. Chang et al.   JOURNAL OF VIROLOGY

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

The genome sequence of Atlantic cod reveals a unique immune system

(2011) Bastiaan Star et al.   NATURE

Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution

(2010) Bei Huang et al.   BMC IMMUNOLOGY

Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing

(2010) Petr Broz et al.   Cell Host & Microbe

Recognition of viruses by cytoplasmic sensors

(2010) Courtney Wilkins et al.   CURRENT OPINION IN IMMUNOLOGY

Phylogenetic and expression analysis of lamprey toll-like receptors

(2010) Jun Kasamatsu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Deep sequencing of the innate immune transcriptomic response of zebrafish embryos to Salmonella infection

(2010) Anita Ordas et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular cloning and characterization of Toll-like receptor 14 in Japanese flounder, Paralichthys olivaceus

(2010) Seong Don Hwang et al.   FISH & SHELLFISH IMMUNOLOGY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

A Unique Feature of Toll/IL-1 Receptor Domain-Containing Adaptor Protein Is Partially Responsible for Lipopolysaccharide Insensitivity in Zebrafish with a Highly Conserved Function of Myd88

(2010) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

In Vivo Analysis of Ifn- 1 and Ifn- 2 Signaling in Zebrafish

(2010) D. Aggad et al.   JOURNAL OF IMMUNOLOGY

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome

(2009) Kate Schroder et al.   CURRENT BIOLOGY

NOD-like subfamily of the nucleotide-binding domain and leucine-rich repeat containing family receptors and their expression in channel catfish

(2009) Zhenxia Sha et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses

(2009) S. Lipinski et al.   JOURNAL OF CELL SCIENCE

Evolution of Lipopolysaccharide (LPS) Recognition and Signaling: Fish TLR4 Does Not Recognize LPS and Negatively Regulates NF- B Activation

(2009) M. P. Sepulcre et al.   JOURNAL OF IMMUNOLOGY

The Two Groups of Zebrafish Virus-Induced Interferons Signal via Distinct Receptors with Specific and Shared Chains

(2009) D. Aggad et al.   JOURNAL OF IMMUNOLOGY

The Gene History of Zebrafish tlr4a and tlr4b Is Predictive of Their Divergent Functions

(2009) C. Sullivan et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Antiviral Signaling Protein Plays a Major Role in Induction of the Fish Innate Immune Response against RNA and DNA Viruses

(2009) S. Biacchesi et al.   JOURNAL OF VIROLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish

(2008) Kerry J Laing et al.   BMC EVOLUTIONARY BIOLOGY

Zebrafish as a model for infectious disease and immune function

(2008) Con Sullivan et al.   FISH & SHELLFISH IMMUNOLOGY