β -Glucuronidase- and OATP2B1-mediated drug interaction of scutellarin in Dengzhan Xixin Injection: A formulation aspect

Organic anion transporter 3 (OAT3)-mediated transport of dicaffeoylquinic acids and prediction of potential drug-drug interaction

(2019) Yan Wang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Reviewing the mechanisms of natural product-drug interactions involving efflux transporters and metabolic enzymes

(2019) Clarissa Feltrin et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Renal organic anion transporters in drug–drug interactions and diseases

(2018) Xiaokui Huo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Clinical benefits and pharmacology of scutellarin: A comprehensive review

(2018) Liping Wang et al.   PHARMACOLOGY & THERAPEUTICS

A highly selective ratiometric fluorescent probe for real-time imaging of β -glucuronidase in living cells and zebrafish

(2018) Xiaokui Huo et al.   SENSORS AND ACTUATORS B-CHEMICAL

Engineering yeast for the production of breviscapine by genomic analysis and synthetic biology approaches

(2018) Xiaonan Liu et al.   Nature Communications

Highly Selective NIR Probe for Intestinal β-Glucuronidase and High-Throughput Screening Inhibitors to Therapy Intestinal Damage

(2018) Lei Feng et al.   ACS Sensors

Structure-activity relationships of flavonoids as natural inhibitors against E. coli β-glucuronidase

(2017) Zi-Miao Weng et al.   FOOD AND CHEMICAL TOXICOLOGY

Comparative pharmacokinetic study of baicalin and its metabolites after oral administration of baicalin and Chaiqin Qingning capsule in normal and febrile rats

(2017) Xiao-Kui Huo et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Intestinal Drug Interactions Mediated by OATPs: A Systematic Review of Preclinical and Clinical Findings

(2017) Jingjing Yu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential

(2017) Xiaokui Huo et al.   JOURNAL OF PINEAL RESEARCH

Therapeutic Effects of Breviscapine in Cardiovascular Diseases: A Review

(2017) Jialiang Gao et al.   Frontiers in Pharmacology

Pharmacokinetic herb–drug interactions with traditional Chinese medicine: progress, causes of conflicting results and suggestions for future research

(2016) Bing-Liang Ma et al.   DRUG METABOLISM REVIEWS

Scutellarin attenuates vasospasm through the Erk5-KLF2-eNOS pathway after subarachnoid hemorrhage in rats

(2016) Qiang Li et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Safety Surveillance of Traditional Chinese Medicine: Current and Future

(2015) Shwu-Huey Liu et al.   DRUG SAFETY

Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia

(2015) Yun Yuan et al.   Journal of Neuroinflammation

Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake

(2015) Fengjiao Wen et al.   PHARMACEUTICAL BIOLOGY

Clinical tolerability and pharmacokinetics of Erigerontis hydroxybenzene injection: Results of a randomized phase I study in healthy Chinese volunteers

(2015) Wen-Zheng Ju et al.   PHYTOMEDICINE

Mixed Polyethylene Glycol-Modified Breviscapine-Loaded Solid Lipid Nanoparticles for Improved Brain Bioavailability: Preparation, Characterization, and In Vivo Cerebral Microdialysis Evaluation in Adult Sprague Dawley Rats

(2014) Zhidong Liu et al.   AAPS PHARMSCITECH

Sustained release and enhanced bioavailability of injectable scutellarin-loaded bovine serum albumin nanoparticles

(2014) Yuanfeng Wei et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Scutellarin and caffeic acid ester fraction, active components of Dengzhanxixin injection, upregulate neurotrophins synthesis and release in hypoxia/reoxygenation rat astrocytes

(2013) Lijuan Chai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats

(2013) Chao Guo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Intestinal transport of scutellarein and scutellarin and first-pass metabolism by UDP-glucuronosyltransferase-mediated glucuronidation of scutellarein and hydrolysis of scutellarin

(2011) Yazhi Wang et al.   XENOBIOTICA

Measurement of caffeic and ferulic acid equivalents in plasma after coffee consumption: Small intestine and colon are key sites for coffee metabolism

(2009) Mathieu Renouf et al.   MOLECULAR NUTRITION & FOOD RESEARCH