Model-driven intracellular redox status modulation for increasing isobutanol production in Escherichia coli

NADH plays the vital role for chiral pure D-(−)-2,3-butanediol production inBacillus subtilisunder limited oxygen conditions

(2014) Jing Fu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production

(2014) Justyna Nocon et al.   METABOLIC ENGINEERING

Optimal cofactor swapping can increase the theoretical yield for chemical production in Escherichia coli and Saccharomyces cerevisiae

(2014) Zachary A. King et al.   METABOLIC ENGINEERING

A de novo NADPH generation pathway for improving lysine production of Corynebacterium glutamicum by rational design of the coenzyme specificity of glyceraldehyde 3-phosphate dehydrogenase

(2014) Rajesh Reddy Bommareddy et al.   METABOLIC ENGINEERING

Model-Driven Redox Pathway Manipulation for Improved Isobutanol Production in Bacillus subtilis Complemented with Experimental Validation and Metabolic Profiling Analysis

(2014) Haishan Qi et al.   PLoS One

Metabolic and transcriptional response of Escherichia coli with a NADP+-dependent glyceraldehyde 3-phosphate dehydrogenase from Streptococcus mutans

(2013) Sara Centeno-Leija et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Enhancement of succinate production by metabolically engineered Escherichia coli with co-expression of nicotinic acid phosphoribosyltransferase and pyruvate carboxylase

(2013) Jiangfeng Ma et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cofactor engineering through heterologous expression of an NADH oxidase and its impact on metabolic flux redistribution in Klebsiella pneumoniae

(2013) Xiao-Jun Ji et al.   Biotechnology for Biofuels

Activation of glyoxylate pathway without the activation of its related gene in succinate-producing engineered Escherichia coli

(2013) Li-Wen Zhu et al.   METABOLIC ENGINEERING

Model-driven rebalancing of the intracellular redox state for optimization of a heterologous n-butanol pathway in Escherichia coli

(2013) Jae Hyung Lim et al.   METABOLIC ENGINEERING

Engineering of carboligase activity reaction in Candida glabrata for acetoin production

(2013) Shubo Li et al.   METABOLIC ENGINEERING

Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement

(2013) Di Huang et al.   Microbial Cell Factories

Engineering NAD+ availability for Escherichia coli whole-cell biocatalysis: a case study for dihydroxyacetone production

(2013) Yongjin J Zhou et al.   Microbial Cell Factories

Engineering Escherichia coli with acrylate pathway genes for propionic acid synthesis and its impact on mixed-acid fermentation

(2012) Vijayalakshmi Kandasamy et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effects of NADH kinase on NADPH-dependent biotransformation processes in Escherichia coli

(2012) Won-Heong Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Elucidating and reprogramming Escherichia coli metabolisms for obligate anaerobic n-butanol and isobutanol production

(2012) Cong T. Trinh   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Activating transhydrogenase and NAD kinase in combination for improving isobutanol production

(2012) Aiqin Shi et al.   METABOLIC ENGINEERING

Rational improvement of the engineered isobutanol-producing Bacillus subtilis by elementary mode analysis

(2012) Shanshan Li et al.   Microbial Cell Factories

Redesigning Escherichia coli Metabolism for Anaerobic Production of Isobutanol

(2011) Cong T. Trinh et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

In silico improvement of heterologous biosynthesis of erythromycin precursor 6-deoxyerythronolide B in Escherichia coli

(2011) Hailin Meng et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli

(2011) Sabine Bastian et al.   METABOLIC ENGINEERING

A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011

(2011) J. D. Orth et al.   Molecular Systems Biology

Genome-Scale Consequences of Cofactor Balancing in Engineered Pentose Utilization Pathways in Saccharomyces cerevisiae

(2011) Amit Ghosh et al.   PLoS One

Engineering of Corynebacterium glutamicum with an NADPH-Generating Glycolytic Pathway for L-Lysine Production

(2010) S. Takeno et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Engineering Corynebacterium glutamicum for isobutanol production

(2010) Kevin Michael Smith et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Evaluation of Genetic Manipulation Strategies on d-Lactate Production by Escherichia coli

(2010) Li Zhou et al.   CURRENT MICROBIOLOGY

Manipulating redox and ATP balancing for improved production of succinate in E. coli

(2010) Amarjeet Singh et al.   METABOLIC ENGINEERING

Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes

(2009) Shota Atsumi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Different Biochemical Mechanisms Ensure Network-Wide Balancing of Reducing Equivalents in Microbial Metabolism

(2009) T. Fuhrer et al.   JOURNAL OF BACTERIOLOGY

ATP Regulates Calcium Efflux and Growth in E. coli

(2009) Riffat Naseem et al.   JOURNAL OF MOLECULAR BIOLOGY

Computational analysis of phenotypic space in heterologous polyketide biosynthesis—Applications to Escherichia coli, Bacillus subtilis, and Saccharomyces cerevisiae

(2009) Brett A. Boghigian et al.   JOURNAL OF THEORETICAL BIOLOGY

Genes restoring redox balance in fermentation-deficient E. coli NZN111

(2009) Amarjeet Singh et al.   METABOLIC ENGINEERING

An integrated network approach identifies the isobutanol response network of Escherichia coli

(2009) Mark P Brynildsen et al.   Molecular Systems Biology

Replacing Escherichia coli NAD-dependent glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with a NADP-dependent enzyme from Clostridium acetobutylicum facilitates NADPH dependent pathways

(2008) Irene Martínez et al.   METABOLIC ENGINEERING

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

(2008) Shota Atsumi et al.   NATURE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Performance and emission characteristics of a diesel engine using isobutanol–diesel fuel blends

(2008) Murat Karabektas et al.   RENEWABLE ENERGY

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING