Rab proteins as regulators of lipid droplet formation and lipolysis

Depletion of Rab32 decreases intracellular lipid accumulation and induces lipolysis through enhancing ATGL expression in hepatocytes

(2016) Qing Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alcoholic vs non-alcoholic fatty liver in rats: distinct differences in endocytosis and vesicle trafficking despite similar pathology

(2016) Karuna Rasineni et al.   BMC GASTROENTEROLOGY

The role of cullin 5-containing ubiquitin ligases

(2016) Fumihiko Okumura et al.   Cell Division

The small GTPase Rab7 as a central regulator of hepatocellular lipophagy

(2015) Barbara Schroeder et al.   HEPATOLOGY

Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein

(2015) Fiona O'Mahony et al.   HEPATOLOGY

RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes

(2015) Soujiro Marubashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions

(2015) K. Takashima et al.   JOURNAL OF CELL SCIENCE

Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation

(2015) Mark T. Handley et al.   Open Biology

Regulation of autophagy by the Rab GTPase network

(2014) X Ao et al.   CELL DEATH AND DIFFERENTIATION

SOCS proteins in regulation of receptor tyrosine kinase signaling

(2014) Julhash U. Kazi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Golgi compartmentation and identity

(2014) Effrosyni Papanikou et al.   CURRENT OPINION IN CELL BIOLOGY

Rab8a-AS160-MSS4 Regulatory Circuit Controls Lipid Droplet Fusion and Growth

(2014) Lizhen Wu et al.   DEVELOPMENTAL CELL

Toward a Comprehensive Map of the Effectors of Rab GTPases

(2014) Alison K. Gillingham et al.   DEVELOPMENTAL CELL

Myosin Vc Interacts with Rab32 and Rab38 Proteins and Works in the Biogenesis and Secretion of Melanosomes

(2014) Jarred J. Bultema et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab18 and a Rab18 GEF complex are required for normal ER structure

(2014) Andreas Gerondopoulos et al.   JOURNAL OF CELL BIOLOGY

Recent Advances in Understanding Proteins Involved in Lipid Droplet Formation, Growth and Fusion

(2014) Jolene S.Y. Tan et al.   Journal of Genetics and Genomics

ARFGAP1 Is Dynamically Associated with Lipid Droplets in Hepatocytes

(2014) Joan Gannon et al.   PLoS One

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

(2014) Florian Wilfling et al.   eLife

Rab GTPases Associate with Isolated Lipid Droplets (LDs) and Show Altered Content After Ethanol Administration: Potential Role in Alcohol-Impaired LD Metabolism

(2013) Karuna Rasineni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans

(2013) Ryan P. Liegel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

β-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation

(2013) Analyn Lizaso et al.   Autophagy

FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes

(2013) Tan Hooi Min Grahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endocytic Rabs in membrane trafficking and signaling

(2013) Johannes Numrich et al.   BIOLOGICAL CHEMISTRY

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

Localization of Rab proteins to peroxisomes: A proteomics and immunofluorescence study

(2013) Thomas Gronemeyer et al.   FEBS LETTERS

Mutation Spectrum inRAB3GAP1,RAB3GAP2, andRAB18and Genotype-Phenotype Correlations in Warburg Micro Syndrome and Martsolf Syndrome

(2013) Mark T. Handley et al.   HUMAN MUTATION

Rab GTPases and membrane identity: Causal or inconsequential?

(2013) Francis A. Barr   JOURNAL OF CELL BIOLOGY

Targeting of the Arf-GEF GBF1 to lipid droplets and Golgi membranes

(2013) S. Bouvet et al.   JOURNAL OF CELL SCIENCE

Protein Correlation Profiles Identify Lipid Droplet Proteins with High Confidence

(2013) Natalie Krahmer et al.   MOLECULAR & CELLULAR PROTEOMICS

The biophysics and cell biology of lipid droplets

(2013) Abdou Rachid Thiam et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Small GTPase Rab40c Associates with Lipid Droplets and Modulates the Biogenesis of Lipid Droplets

(2013) Ran Tan et al.   PLoS One

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function

(2013) A. R. Thiam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cidea controls lipid droplet fusion and lipid storage in brown and white adipose tissue

(2013) LiZhen Wu et al.   Science China-Life Sciences

GTPase Networks in Membrane Traffic

(2012) Emi Mizuno-Yamasaki et al.   Annual Review of Biochemistry

CIDE Proteins and Lipid Metabolism

(2012) Li Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rab GTPase localization and Rab cascades in Golgi transport

(2012) Suzanne R. Pfeffer   BIOCHEMICAL SOCIETY TRANSACTIONS

RAB3GAP1,RAB3GAP2andRAB18: disease genes in Micro and Martsolf syndromes

(2012) Mark T. Handley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Rab proteins of the endoplasmic reticulum: functions and interactors

(2012) Carolina Ortiz Sandoval et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Maturation of autophagosomes and endosomes: A key role for Rab7

(2012) Juha M.T. Hyttinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Are Rab proteins the link between Golgi organization and membrane trafficking?

(2012) Shijie Liu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Controlling the size of lipid droplets: lipid and protein factors

(2012) Hongyuan Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Lipid droplet formation on opposing sides of the endoplasmic reticulum

(2012) Stephen L. Sturley et al.   JOURNAL OF LIPID RESEARCH

Characterization of the Lipid Droplet Proteome of a Clonal Insulin-producing β-Cell Line (INS-1 832/13)

(2012) Sara Larsson et al.   JOURNAL OF PROTEOME RESEARCH

Role for TBC1D20 and Rab1 in Hepatitis C Virus Replication via Interaction with Lipid Droplet-Bound Nonstructural Protein 5A

(2012) I. Nevo-Yassaf et al.   JOURNAL OF VIROLOGY

Rab32 Is Important for Autophagy and Lipid Storage in Drosophila

(2012) Chao Wang et al.   PLoS One

Loss-of-Function Mutations in RAB18 Cause Warburg Micro Syndrome

(2011) Danai Bem et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GBF1-Arf-COPI-ArfGAP–mediated Golgi-to-ER Transport Involved in Regulation of Lipid Homeostasis

(2011) Kouhei Takashima et al.   CELL STRUCTURE AND FUNCTION

Rab6, Rab8, and MICAL3 Cooperate in Controlling Docking and Fusion of Exocytotic Carriers

(2011) Ilya Grigoriev et al.   CURRENT BIOLOGY

Rab8 GTPase as a regulator of cell shape

(2011) Johan Peränen   Cytoskeleton

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Packaging of Fat: An Evolving Model of Lipid Droplet Assembly and Expansion

(2011) Dawn L. Brasaemle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

(2011) Jingyi Gong et al.   JOURNAL OF CELL BIOLOGY

Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity

(2011) Marina R. Pulido et al.   PLoS One

FSP27 Promotes Lipid Droplet Clustering and Then Fusion to Regulate Triglyceride Accumulation

(2011) Srikarthika Jambunathan et al.   PLoS One

Not Just Fat: The Structure and Function of the Lipid Droplet

(2011) T. Fujimoto et al.   Cold Spring Harbor Perspectives in Biology

Rab7: Role of its protein interaction cascades in endo-lysosomal traffic

(2010) Tuanlao Wang et al.   CELLULAR SIGNALLING

Rab GEFs and GAPs

(2010) Francis Barr et al.   CURRENT OPINION IN CELL BIOLOGY

Rab32 Modulates Apoptosis Onset and Mitochondria-associated Membrane (MAM) Properties

(2010) Michael Bui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores

(2009) Perry E. Bickel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Rab family small G proteins in regulation of epithelial apical junctions

(2009) Noriyuki Nishimura   Frontiers in Bioscience-Landmark

Coatomer-dependent protein delivery to lipid droplets

(2009) K. G. Soni et al.   JOURNAL OF CELL SCIENCE

Varp Is a Novel Rab32/38-binding Protein That Regulates Tyrp1 Trafficking in Melanocytes

(2009) Kanako Tamura et al.   MOLECULAR BIOLOGY OF THE CELL

Defining the boundaries: Rab GEFs and GAPs

(2009) R. M. Nottingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell biology of lipid droplets

(2008) Christoph Thiele et al.   CURRENT OPINION IN CELL BIOLOGY

Minireview: Lipid Droplets in Lipogenesis and Lipolysis

(2008) Nicole A. Ducharme et al.   ENDOCRINOLOGY

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

(2008) Martina Schweiger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab18 and Rab43 have key roles in ER-Golgi trafficking

(2008) S. Y. Dejgaard et al.   JOURNAL OF CELL SCIENCE

COPI Complex Is a Regulator of Lipid Homeostasis

(2008) Mathias Beller et al.   PLOS BIOLOGY