A New Role for the Aldosterone/Mineralocorticoid Receptor Pathway in the Development of Mitral Valve Prolapse

Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation

(2018) Kathryn H. Driesbaugh et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Neutrophil Gelatinase-Associated Lipocalin from immune cells is mandatory for aldosterone-induced cardiac remodeling and inflammation

(2018) Mathieu Buonafine et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts

(2017) Ernesto Martínez-Martínez et al.   Scientific Reports

CD45 Expression in Mitral Valve Endothelial Cells After Myocardial InfarctionNovelty and Significance

(2016) Joyce Bischoff et al.   CIRCULATION RESEARCH

Protective Effect of Spironolactone on Endothelial-to-Mesenchymal Transition in HUVECs via Notch Pathway

(2015) Xiao Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

CD14 as a Mediator of the Mineralocorticoid Receptor–Dependent Anti-apolipoprotein A-1 IgG Chronotropic Effect on Cardiomyocytes

(2015) Tiphaine Mannic et al.   ENDOCRINOLOGY

Reciprocal interactions between mitral valve endothelial and interstitial cells reduce endothelial-to-mesenchymal transition and myofibroblastic activation

(2015) Kayle Shapero et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitral valve disease—morphology and mechanisms

(2015) Robert A. Levine et al.   Nature Reviews Cardiology

Developmental pathways and endothelial to mesenchymal transition in canine myxomatous mitral valve disease

(2015) Chi-Chien Lu et al.   VETERINARY JOURNAL

TAK-242, a Toll-Like Receptor 4 Antagonist, Protects against Aldosterone-Induced Cardiac and Renal Injury

(2015) Yide Zhang et al.   PLoS One

Epidemiology and Pathophysiology of Mitral Valve Prolapse

(2014) Francesca N. Delling et al.   CIRCULATION

Cardiac valve cells and their microenvironment—insights from in vitro studies

(2014) Huan Wang et al.   Nature Reviews Cardiology

Cardiovascular Complications Associated With Primary Aldosteronism

(2013) Sébastien Savard et al.   HYPERTENSION

Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data

(2012) Alexia Hulin et al.   CARDIOVASCULAR PATHOLOGY

A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone

(2011) Natalia López-Andrés et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitral Valve Endothelial Cells With Osteogenic Differentiation Potential

(2010) Jill Wylie-Sears et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Efficacy of Spironolactone on Survival in Dogs with Naturally Occurring Mitral Regurgitation Caused by Myxomatous Mitral Valve Disease

(2010) F. Bernay et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Active Adaptation of the Tethered Mitral Valve

(2009) Jacob P. Dal-Bianco et al.   CIRCULATION

Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves

(2008) Vishal Gupta et al.   CARDIOVASCULAR PATHOLOGY

Aldosterone Induces Cardiotrophin-1 Expression in HL-1 Adult Cardiomyocytes

(2008) Natalia López-Andrés et al.   ENDOCRINOLOGY

Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse

(2008) Olivia Wendling et al.   GENESIS