Journal
CHINESE JOURNAL OF CHEMISTRY
Volume 38, Issue 7, Pages 683-689Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.202000109
Keywords
Asymmetric catalysis; Dearomatization; Homogeneous catalysis; Palladium; Phenol
Categories
Funding
- MOST [2016YFA0202900]
- NSFC [21821002, 91856201]
- Chinese Academy of Sciences [XDB20000000, QYZDY-SSW-SLH012]
Ask authors/readers for more resources
The Summary of main observation and conclusion Asymmetric arylative dearomatization reactions of para-aminophenols are realized by a Pd-catalyst consisting of a TADDOL (alpha,alpha,alpha',alpha'-tetraaryl-2,2-disubstituted 1,3-dioxolane-4,5-dimethanol)-derived chiral phosphoramidite ligand. The tetracyclic products bearing the key skeleton of Erythrina alkaloids are afforded in reasonable yields (up to 73%) with good to excellent enantioselectivity (up to 97% ee). Concise total synthesis of (-)-3-demethoxyerythratidinone is achieved by employing this method as the key step.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available