Scarless wound healing: finding the right cells and signals

Extracorporeal shock waves modulate myofibroblast differentiation of adipose-derived stem cells

(2016) Letizia Rinella et al.   WOUND REPAIR AND REGENERATION

Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages

(2016) Beate M. Lichtenberger et al.   Nature Communications

Stem Cells in Skin Wound Healing: Are We There Yet?

(2016) Mariana Teixeira Cerqueira et al.   Advances in Wound Care

Potency of umbilical cord blood- and Wharton’s jelly-derived mesenchymal stem cells for scarless wound healing

(2016) Hanako Doi et al.   Scientific Reports

miRNA Control of Tissue Repair and Regeneration

(2015) Chandan K. Sen et al.   AMERICAN JOURNAL OF PATHOLOGY

The number of immune cells is lower in healthy oral mucosa compared to skin and does not increase after scarring

(2015) Judith E. Glim et al.   ARCHIVES OF ORAL BIOLOGY

Phenotypic and functional modulation of 20–30 year old dermal fibroblasts by mid- and late-gestational keratinocytes in vitro

(2015) Zhe Wang et al.   BURNS

Improved cutaneous wound healing after intraperitoneal injection of alpha-melanocyte-stimulating hormone

(2015) Kênia Soares de Souza et al.   EXPERIMENTAL DERMATOLOGY

Inhibition of Wnt/β-catenin pathway promotes regenerative repair of cutaneous and cartilage injury

(2015) Dikshya Bastakoty et al.   FASEB JOURNAL

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

(2015) Soung-Hoon Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

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(2015) Christiane Gras et al.   MOLECULAR MEDICINE

Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation and Attenuates Adverse Cardiac Remodeling in the Infarcted Diabetic Heart

(2015) Dinender K. Singla et al.   PLoS One

Identification and isolation of a dermal lineage with intrinsic fibrogenic potential

(2015) Y. Rinkevich et al.   SCIENCE

Understanding fibroblast heterogeneity in the skin

(2015) Ryan R. Driskell et al.   TRENDS IN CELL BIOLOGY

Endothelial-to-mesenchymal transition induced by Wnt 3a in keloid pathogenesis

(2015) Won Jai Lee et al.   WOUND REPAIR AND REGENERATION

Mesenchymal stem cell-conditioned medium accelerates wound healing with fewer scars

(2015) Meirong Li et al.   International Wound Journal

Wnt signaling induces epithelial differentiation during cutaneous wound healing

(2015) Khosrow S Houschyar et al.   Organogenesis

Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately

(2015) Yan Shi et al.   Stem Cell Research & Therapy

Dynamic Expression of Novel MiRNA Candidates and MiRNA-34 Family Members in Early- to Mid-Gestational Fetal Keratinocytes Contributes to Scarless Wound Healing by Targeting the TGF-β Pathway

(2015) Feng Zhao et al.   PLoS One

Extracellular matrix components of oral mucosa differ from skin and resemble that of foetal skin

(2014) Judith E. Glim et al.   ARCHIVES OF ORAL BIOLOGY

LEF1 and B9L Shield  -Catenin from Inactivation by Axin, Desensitizing Colorectal Cancer Cells to Tankyrase Inhibitors

(2014) M. de la Roche et al.   CANCER RESEARCH

Gene expression in fetal murine keratinocytes and fibroblasts

(2014) Michael S. Hu et al.   JOURNAL OF SURGICAL RESEARCH

A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling

(2014) Michael Monaghan et al.   MOLECULAR THERAPY

A Randomized Controlled Trial of the embrace Advanced Scar Therapy Device to Reduce Incisional Scar Formation

(2014) Michael T. Longaker et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Reversible Modulation of Myofibroblast Differentiation in Adipose-Derived Mesenchymal Stem Cells

(2014) Vivek D. Desai et al.   PLoS One

Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth

(2014) Vikram Sabapathy et al.   PLoS One

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

The therapeutic potential of a C-X-C chemokine receptor type 4 (CXCR-4) antagonist on hypertrophic scarring in vivo

(2014) Jie Ding et al.   WOUND REPAIR AND REGENERATION

Modulation of the inflammatory response by increasing fetal wound size or interleukin-10 overexpression determines wound phenotype and scar formation

(2014) Michael W. Morris et al.   WOUND REPAIR AND REGENERATION

Intradermal adipocytes mediate fibroblast recruitment during skin wound healing

(2013) B. A. Schmidt et al.   DEVELOPMENT

Distinct fibroblast lineages determine dermal architecture in skin development and repair

(2013) Ryan R. Driskell et al.   NATURE

Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding

(2013) Denise Gay et al.   NATURE MEDICINE

The embrace Device Significantly Decreases Scarring following Scar Revision Surgery in a Randomized Controlled Trial

(2013) Angeline F. Lim et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Interleukin-10 reduces scar formation in both animal and human cutaneous wounds: Results of two preclinical and phase II randomized control studies

(2013) Ingrid Kieran et al.   WOUND REPAIR AND REGENERATION

Activity of mesenchymal stem cells in therapies for chronic skin wound healing

(2013) Austin Nuschke   Organogenesis

Distinct contribution of stem and progenitor cells to epidermal maintenance

(2012) Guilhem Mascré et al.   NATURE

Lineage tracing and genetic ablation of ADAM12+ perivascular cells identify a major source of profibrotic cells during acute tissue injury

(2012) Sophie Dulauroy et al.   NATURE MEDICINE

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

β-catenin signaling

(2011) Anna P. Lam et al.   CURRENT OPINION IN RHEUMATOLOGY

Reprogramming adult dermis to a neonatal state through epidermal activation of  -catenin

(2011) C. A. Collins et al.   DEVELOPMENT

Hair follicle dermal papilla cells at a glance

(2011) R. R. Driskell et al.   JOURNAL OF CELL SCIENCE

Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling

(2011) Victor W Wong et al.   NATURE MEDICINE

Scarless Fetal Wound Healing: A Basic Science Review

(2010) Barrett J. Larson et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

MicroRNA Profiling in Mid- and Late-Gestational Fetal Skin: Implication for Scarless Wound Healing

(2010) Jie Cheng et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells

(2009) Jeffrey Biernaskie et al.   Cell Stem Cell

Interaction of Wingless Protein (Wnt), Transforming Growth Factor-β1, and Hyaluronan Production in Fetal and Postnatal Fibroblasts

(2009) Antoine L. Carre et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Human skin wounds: A major and snowballing threat to public health and the economy

(2009) Chandan K. Sen et al.   WOUND REPAIR AND REGENERATION

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Inhibitors of Dipeptidyl Peptidase IV-Like Activity Mediate Antifibrotic Effects in Normal and Keloid-Derived Skin Fibroblasts

(2007) Anja Thielitz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY