4.5 Article

Cladosporactone A, a Unique Polyketide with 7-Methylisochromen-3-one Skeleton from the Deep-Sea-Derived Fungus Cladosporium cladosporioides

Journal

CHEMISTRY & BIODIVERSITY
Volume 17, Issue 6, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.202000158

Keywords

deep sea; Cladosporium cladosporioides; fungus; polyketide

Funding

  1. COMRA program [DY135-B2-08]
  2. National Natural Science Foundation of China [21877022]

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A unique polyketide cladosporactone A along with eight known compounds were isolated from the deep-sea-derived Cladosporium cladosporioides. The structure of cladosporactone A was established by spectroscopic analyses, and the absolute configuration was clarified by the theoretical ECD calculation. Cladosporactone A is the first member of polyketide with the 7-methylisochromen-3-one skeleton.

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