Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors

Recipient c-Kit Lineage Cells Repopulate Smooth Muscle Cells of Transplant Arteriosclerosis in Mouse Models

(2019) Zhichao Ni et al.   CIRCULATION RESEARCH

Single-Cell RNA-Sequencing and Metabolomics Analyses Reveal the Contribution of Perivascular Adipose Tissue Stem Cells to Vascular Remodeling

(2019) Wenduo Gu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing

(2019) Wenduo Gu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations

(2019) Aditya S. Kalluri et al.   CIRCULATION

Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies—Statement From ATVB CouncilHighlights

(2018) Peggy Robinet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties

(2018) Taku Wakabayashi et al.   Cell Stem Cell

Genetic Lineage Tracing of Sca-1+Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart

(2018) Ronald J. Vagnozzi et al.   CIRCULATION

Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis

(2018) Li Zhang et al.   CIRCULATION RESEARCH

Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques

(2018) Lukas Tomas et al.   EUROPEAN HEART JOURNAL

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Endothelial Cell Metabolism

(2018) Guy Eelen et al.   PHYSIOLOGICAL REVIEWS

Endothelial Cell Metabolism in Health and Disease

(2018) Katerina Rohlenova et al.   TRENDS IN CELL BIOLOGY

Adult Stem Cells in Vascular Remodeling

(2018) Dong Wang et al.   Theranostics

Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease

(2018) Daniel G. Sedding et al.   Frontiers in Immunology

Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities

(2018) Austin I. McDonald et al.   Cell Stem Cell

Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells

(2018) Subba Rao Mekala et al.   CIRCULATION RESEARCH

Genetic lineage tracing analysis of c-kit+ stem/progenitor cells revealed a contribution to vascular injury-induced neointimal lesions

(2018) Qishan Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1–Positive Cells in the Adult Mouse Heart

(2018) Lauren E. Neidig et al.   CIRCULATION

Cardiac Sca-1 + Cells Are Not Intrinsic Stem Cells for Myocardial Development, Renewal, and Repair

(2018) Lu Zhang et al.   CIRCULATION

Fate Mapping of Sca1 + Cardiac Progenitor Cells in the Adult Mouse Heart

(2018) Juan Tang et al.   CIRCULATION

Glycolytic Switch Is Required for Transdifferentiation to Endothelial Lineage

(2018) Li Lai et al.   CIRCULATION

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels

(2018) Lina Dobnikar et al.   Nature Communications

Enhancing the precision of genetic lineage tracing using dual recombinases

(2017) Lingjuan He et al.   NATURE MEDICINE

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair

(2017) Urmas Roostalu et al.   CIRCULATION RESEARCH

Identification of blood vascular endothelial stem cells by the expression of protein C receptor

(2016) Qing Cissy Yu et al.   CELL RESEARCH

Functional Definition of Progenitors Versus Mature Endothelial Cells Reveals Key SoxF-Dependent Differentiation ProcessClinical Perspective

(2016) Jatin Patel et al.   CIRCULATION

Design and Analysis of Single-Cell Sequencing Experiments

(2015) Dominic Grün et al.   CELL

Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes

(2015) Qiaozhen Liu et al.   CELL RESEARCH

c-kit+ cells adopt vascular endothelial but not epithelial cell fates during lung maintenance and repair

(2015) Qiaozhen Liu et al.   NATURE MEDICINE

Resident c-kit+ cells in the heart are not cardiac stem cells

(2015) Nishat Sultana et al.   Nature Communications

Characterization of a Resident Population of Adventitial Macrophage Progenitor Cells in Postnatal Vasculature

(2014) Peter J. Psaltis et al.   CIRCULATION RESEARCH

c-kit+ cells minimally contribute cardiomyocytes to the heart

(2014) Jop H. van Berlo et al.   NATURE

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

Adventitial Stem Cells in Vein Grafts Display Multilineage Potential That Contributes to Neointimal Formation

(2013) Yikuan Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Parabiosis in Mice: A Detailed Protocol

(2013) Paniz Kamran et al.   Jove-Journal of Visualized Experiments

Lineage Tracing

(2012) Kai Kretzschmar et al.   CELL

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Stem Cell Factor Receptor/c-Kit: From Basic Science to Clinical Implications

(2012) Johan Lennartsson et al.   PHYSIOLOGICAL REVIEWS

Generation of Functional Blood Vessels from a Single c-kit+ Adult Vascular Endothelial Stem Cell

(2012) Shentong Fang et al.   PLOS BIOLOGY

Flanking Recipient Vasculature, Not Circulating Progenitor Cells, Contributes to Endothelium and Smooth Muscle in Murine Allograft Vasculopathy

(2011) Mette K. Hagensen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification and characterization of a resident vascular stem/progenitor cell population in preexisting blood vessels

(2011) Hisamichi Naito et al.   EMBO JOURNAL

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

Stem Cell Therapy for Vascular Regeneration

(2010) Nicholas J. Leeper et al.   CIRCULATION

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Rapid Endothelial Turnover in Atherosclerosis-Prone Areas Coincides With Stem Cell Repair in Apolipoprotein E–Deficient Mice

(2008) Georgios Foteinos et al.   CIRCULATION

Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

(2008) S. Purhonen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA