Olig2 SUMOylation protects against genotoxic damage response by antagonizing p53 gene targeting

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

(2018) Amelie Griveau et al.   CANCER CELL

The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ERα and enhances ERα target gene expression in breast cancer cells

(2018) Beihui Xu et al.   NUCLEIC ACIDS RESEARCH

SUMO protease SENP1 deSUMOylates and stabilizes c-Myc

(2018) Xiao-Xin Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overcoming therapeutic resistance in glioblastoma: the way forward

(2017) Satoru Osuka et al.   JOURNAL OF CLINICAL INVESTIGATION

A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2

(2017) Jing Zhou et al.   Cell Reports

Sequential posttranslational modifications regulate PKC degradation

(2016) Yan Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway

(2016) Shiv K. Singh et al.   Cell Reports

JASSA: a comprehensive tool for prediction of SUMOylation sites and SIMs

(2015) Guillaume Beauclair et al.   BIOINFORMATICS

Spatiotemporal regulation of posttranslational modifications in the DNA damage response

(2015) N. P. Dantuma et al.   EMBO JOURNAL

SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer

(2015) Karolin Eifler et al.   TRENDS IN BIOCHEMICAL SCIENCES

Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

(2014) Juan L. Mateo et al.   GENOME RESEARCH

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

(2014) Bernard Leroy et al.   HUMAN MUTATION

An Amino Terminal Phosphorylation Motif Regulates Intranuclear Compartmentalization of Olig2 in Neural Progenitor Cells

(2014) D. H. Meijer et al.   JOURNAL OF NEUROSCIENCE

Two-way communications between ubiquitin-like modifiers and DNA

(2014) Helle D Ulrich   NATURE STRUCTURAL & MOLECULAR BIOLOGY

GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs

(2014) Qi Zhao et al.   NUCLEIC ACIDS RESEARCH

Neuronal SUMOylation: Mechanisms, Physiology, and Roles in Neuronal Dysfunction

(2014) Jeremy M. Henley et al.   PHYSIOLOGICAL REVIEWS

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

SUMO: A Multifaceted Modifier of Chromatin Structure and Function

(2013) Caelin Cubeñas-Potts et al.   DEVELOPMENTAL CELL

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

(2013) Florian A. Siebzehnrubl et al.   EMBO Molecular Medicine

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Modulation of GluK2a Subunit-containing Kainate Receptors by 14-3-3 Proteins

(2013) Changcheng Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2

(2012) Dimphna H. Meijer et al.   NATURE REVIEWS NEUROSCIENCE

The Central Nervous System-Restricted Transcription Factor Olig2 Opposes p53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma

(2011) Shwetal Mehta et al.   CANCER CELL

Phosphorylation State of Olig2 Regulates Proliferation of Neural Progenitors

(2011) Yu Sun et al.   NEURON

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

In VivoIdentification of Sumoylation Sites by a Signature Tag and Cysteine-targeted Affinity Purification

(2010) Henri A. Blomster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding

(2009) Shwu-Yuan Wu et al.   EMBO JOURNAL

Controlling Hematopoiesis through Sumoylation-Dependent Regulation of a GATA Factor

(2009) Hsiang-Ying Lee et al.   MOLECULAR CELL

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL