Two-way communications between ubiquitin-like modifiers and DNA

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

SUMO-targeted ubiquitin ligases

(2013) Annie M. Sriramachandran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Proteasome-Mediated Processing of Def1, a Critical Step in the Cellular Response to Transcription Stress

(2013) Marcus D. Wilson et al.   CELL

DNA-dependent SUMO modification of PARP-1

(2013) Nicola Zilio et al.   DNA REPAIR

End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1

(2013) Rachel Lescasse et al.   EMBO JOURNAL

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks

(2013) Inbal Mermershtain et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

(2013) Molly C. Kottemann et al.   NATURE

The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

(2013) Agathe Bacquin et al.   NUCLEIC ACIDS RESEARCH

Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex

(2013) Rachel Coulthard et al.   STRUCTURE

Ubiquitin and Proteasomes in Transcription

(2012) Fuqiang Geng et al.   Annual Review of Biochemistry

DNA-binding regulates site-specific ubiquitination of IRF-1

(2012) Vivien Landré et al.   BIOCHEMICAL JOURNAL

Ubiquitylation and degradation of elongating RNA polymerase II: The last resort

(2012) Marcus D. Wilson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

(2012) Francesca Mattiroli et al.   CELL

RNF4 is required for DNA double-strand break repair in vivo

(2012) R Vyas et al.   CELL DEATH AND DIFFERENTIATION

Swi2/Snf2 remodelers: hybrid views on hybrid molecular machines

(2012) Karl-Peter Hopfner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage

(2012) Y. Yin et al.   GENES & DEVELOPMENT

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair

(2012) Y. Galanty et al.   GENES & DEVELOPMENT

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

(2012) Li Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Role for Proliferating Cell Nuclear Antigen in Substrate Recognition by the E3 Ubiquitin Ligase CRL4Cdt2

(2012) Courtney G. Havens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin and SUMO in DNA repair at a glance

(2012) H. D. Ulrich   JOURNAL OF CELL SCIENCE

Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks

(2012) Stephanie Panier et al.   MOLECULAR CELL

A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA

(2012) Joanne L. Parker et al.   NUCLEIC ACIDS RESEARCH

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI

(2012) K. Sato et al.   NUCLEIC ACIDS RESEARCH

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

(2012) J. I. Yeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of the FANCM–MHF complex reveals physical features for functional assembly

(2012) Yuyong Tao et al.   Nature Communications

The Smc complexes in DNA damage response

(2012) Nan Wu et al.   Cell and Bioscience

The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation

(2011) Eric S. Fischer et al.   CELL

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

(2011) Matthew L Bentley et al.   EMBO JOURNAL

Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!

(2011) Andrea Scrima et al.   FEBS LETTERS

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

(2011) Simon Bekker-Jensen et al.   FEBS LETTERS

Mechanism of CRL4Cdt2, a PCNA-dependent E3 ubiquitin ligase

(2011) C. G. Havens et al.   GENES & DEVELOPMENT

Dia2 Controls Transcription by Mediating Assembly of the RSC Complex

(2011) Edward J. Andress et al.   PLoS One

Cooperation of replication Protein A with the ubiquitin ligase Rad18 in DNA damage bypass

(2010) Diana Huttner et al.   CELL CYCLE

The ubiquitous role of ubiquitin in the DNA damage response

(2010) Abdallah Al-Hakim et al.   DNA REPAIR

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

(2010) Jennifer M. Doyle et al.   MOLECULAR CELL

CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

(2010) Richard C. Centore et al.   MOLECULAR CELL

Ubiquitin signalling in DNA replication and repair

(2010) Helle D. Ulrich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rad52 SUMOylation affects the efficiency of the DNA repair

(2010) Veronika Altmannova et al.   NUCLEIC ACIDS RESEARCH

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

The Amino-Terminal TPR Domain of Dia2 Tethers SCFDia2 to the Replisome Progression Complex

(2009) Hiroko Morohashi et al.   CURRENT BIOLOGY

SCFDia2 regulates DNA replication forks during S-phase in budding yeast

(2009) Satoru Mimura et al.   EMBO JOURNAL

PARP-1 transcriptional activity is regulated by sumoylation upon heat shock

(2009) Nadine Martin et al.   EMBO JOURNAL

Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5

(2009) Joanne L Parker et al.   EMBO JOURNAL

Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function

(2009) Simon Messner et al.   FASEB JOURNAL

Role of polycomb proteins Ring1A and Ring1Bin the epigenetic regulation of gene expression

(2009) Miguel Vidal   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast

(2009) Jaehoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Double-Stranded DNA Translocase Activity of Human HLTF in Replication of Damaged DNA

(2009) A. Blastyak et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural and Functional Insights into the Roles of the Mms21 Subunit of the Smc5/6 Complex

(2009) Xinyuan Duan et al.   MOLECULAR CELL

Docking of a Specialized PIP Box onto Chromatin-Bound PCNA Creates a Degron for the Ubiquitin Ligase CRL4Cdt2

(2009) Courtney G. Havens et al.   MOLECULAR CELL

Regulation of damage recognition in mammalian global genomic nucleotide excision repair

(2009) Kaoru Sugasawa   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Principles of ubiquitin and SUMO modifications in DNA repair

(2009) Steven Bergink et al.   NATURE

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

(2009) Jun Huang et al.   NATURE CELL BIOLOGY

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

(2009) Simon Bekker-Jensen et al.   NATURE CELL BIOLOGY

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

(2009) M. Harreman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsic Negative Cell Cycle Regulation Provided by PIP Box- and Cul4Cdt2-Mediated Destruction of E2f1 during S Phase

(2008) Shusaku T. Shibutani et al.   DEVELOPMENTAL CELL

Poly ADP-ribose polymerase-1: An international molecule of mystery

(2008) Bethany C. Woodhouse et al.   DNA REPAIR

SUMO modification of PCNA is controlled by DNA

(2008) Joanne L Parker et al.   EMBO JOURNAL

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

(2008) T. Abbas et al.   GENES & DEVELOPMENT

The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

(2008) Y. Kim et al.   GENES & DEVELOPMENT

Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

(2008) Yuri Tsuji et al.   GENES TO CELLS

CDK Inhibitor p21 Is Degraded by a Proliferating Cell Nuclear Antigen-coupled Cul4-DDB1Cdt2Pathway during S Phase and after UV Irradiation

(2008) Hideo Nishitani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinating the Initial Steps of Base Excision Repair

(2008) Megan E. Fitzgerald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated Proteolysis of DNA Polymerase η during the DNA-Damage Response in C. elegans

(2008) Seung-Hwan Kim et al.   MOLECULAR CELL

Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

(2008) Adelina A. Davies et al.   MOLECULAR CELL

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

(2008) A. Niimi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases fromSaccharomyces cerevisiaeandOryza sativa

(2008) Rintaro Suzuki et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Architecture and Assembly of Poly-SUMO Chains on PCNA in Saccharomyces cerevisiae

(2007) Hanna Windecker et al.   JOURNAL OF MOLECULAR BIOLOGY