Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy
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Title
Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy
Authors
Keywords
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Journal
Cell Communication and Signaling
Volume 18, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-03-12
DOI
10.1186/s12964-020-00533-w
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Related references
Note: Only part of the references are listed.- Endothelial to Mesenchymal Transition in Cardiovascular Disease
- (2019) Jason C. Kovacic et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction
- (2019) Anna Walaszczyk et al. AGING CELL
- Gangliosides Contribute to Vascular Insulin Resistance
- (2019) Norihiko Sasaki et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of autophagy in atherosclerosis: foe or friend?
- (2019) Mehdi Hassanpour et al. Journal of Inflammation-London
- Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy
- (2019) Hong-Tao Chen et al. Molecular Cancer
- Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human Diseases
- (2019) Sonsoles Piera-Velazquez et al. PHYSIOLOGICAL REVIEWS
- Rapamycin activates TGF receptor independently of its ligand: implications for endothelial dysfunction
- (2018) Ayumi A. Miyakawa et al. CLINICAL SCIENCE
- Senescent cells: a therapeutic target for cardiovascular disease
- (2018) Bennett G. Childs et al. JOURNAL OF CLINICAL INVESTIGATION
- Senolytics improve physical function and increase lifespan in old age
- (2018) Ming Xu et al. NATURE MEDICINE
- Rapamycin and the inhibition of the secretory phenotype
- (2017) Rong Wang et al. EXPERIMENTAL GERONTOLOGY
- TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion
- (2017) Chao Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Endothelial-to-mesenchymal transition: A novel therapeutic target for cardiovascular diseases
- (2017) Ampadu O. Jackson et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNFα
- (2017) Norihiko Sasaki et al. Oncotarget
- Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways
- (2016) Lisa A. Lesniewski et al. AGING CELL
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors
- (2016) Yi Zhu et al. AGING CELL
- Therapeutic targeting of autophagy in cardiovascular disease
- (2016) Gabriele G. Schiattarella et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
- (2016) Solene M. Evrard et al. Nature Communications
- The mTOR/AP-1/VEGF signaling pathway regulates vascular endothelial cell growth
- (2016) Shuo Wang et al. Oncotarget
- Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells
- (2015) Norihiko Sasaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endothelial-to-mesenchymal transition drives atherosclerosis progression
- (2015) Pei-Yu Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- mTOR: a pharmacologic target for autophagy regulation
- (2015) Young Chul Kim et al. JOURNAL OF CLINICAL INVESTIGATION
- mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
- (2015) Nicolás Herranz et al. NATURE CELL BIOLOGY
- MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
- (2015) Remi-Martin Laberge et al. NATURE CELL BIOLOGY
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- (2015) Bennett G Childs et al. NATURE MEDICINE
- Low Concentration of Rapamycin Inhibits Hemangioma Endothelial Cell Proliferation, Migration, and Vascular Tumor Formation in Mice
- (2014) Ningning Zheng et al. CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
- Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways
- (2014) Cui Yang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The Vascular Endothelium and Human Diseases
- (2014) Peramaiyan Rajendran et al. International Journal of Biological Sciences
- Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2
- (2014) Chen Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Autophagy Regulates Homeostasis of Pluripotency-Associated Proteins in hESCs
- (2013) Yun-Hee Cho et al. STEM CELLS
- Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
- (2012) Vladimir N. Anisimov et al. CELL CYCLE
- GM1 gangliosidosis and Morquio B disease: An update on genetic alterations and clinical findings
- (2011) Anna Caciotti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Four faces of cellular senescence
- (2011) Francis Rodier et al. JOURNAL OF CELL BIOLOGY
- Lysosomal accumulation of Trk protein in brain of GM1-gangliosidosis mouse and its restoration by chemical chaperone
- (2011) Ayumi Takamura et al. JOURNAL OF NEUROCHEMISTRY
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
- (2010) Ivana Bjedov et al. Cell Metabolism
- ICAM-1 Clustering on Endothelial Cells Recruits VCAM-1
- (2010) Jaap D. van Buul et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Using LC3 to monitor autophagy flux in the retinal pigment epithelium
- (2009) Ai Ling Wang et al. Autophagy
- Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
- (2009) David E. Harrison et al. NATURE
- Obesity Increases Vascular Senescence and Susceptibility to Ischemic Injury Through Chronic Activation of Akt and mTOR
- (2009) C.-Y. Wang et al. Science Signaling
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