Article
Chemistry, Multidisciplinary
Andrea Aguilar-Sanchez, Blanca Jalvo, Andreas Mautner, Ville Rissanen, Katri S. Kontturi, Hani Nasser Abdelhamid, Tekla Tammelin, Aji P. Mathew
Summary: This study demonstrates the potential of TEMPO-oxidized cellulose nanofibrils (T-CNF)/poly(vinyl alcohol) (PVA) coatings to develop functionalized membranes with outstanding antifouling performance and stability in the ultrafiltration regime. The coated membranes showed nano-textured surface, altered surface charge, and improved mechanical properties compared to the original substrate. Additionally, the coated membranes exhibited charge specific adsorption and rejection driven by electrostatic interaction and size exclusion mechanisms, leading to reduced fouling when exposed to BSA and E. coli.
Article
Chemistry, Applied
Hippolyte Durand, Isabelle Baussanne, Martine Demeunynck, Jasmine Viger-Gravel, Lyndon Emsley, Michel Bardet, Elisa Zeno, Naceur Belgacem, Julien Bras
Summary: This study presents an ester-containing prodrug of metronidazole covalently bound to cellulose nanofibrils in aqueous suspension using a two-step immobilization procedure based on green chemistry principles. The presence of the drug is confirmed by various characterization methods, and the ester function of the immobilized prodrug allows controlled drug release through specific enzyme activity.
CARBOHYDRATE POLYMERS
(2021)
Article
Agricultural Engineering
Tongtong Liu, Bowen Li, Liang Liu, Yimin Fan, Juan Yu
Summary: Due to irreversible aggregation, achieving nanoscale redispersion of cellulose nanofibrils has been challenging. This study proposed a re-watering strategy to achieve nanoscale redispersion of oven-dried TOCN in water. Water wetting-up was effective in achieving high redispersion rates, and the addition of sodium lignosulfonate further improved the redispersion rate. The redispersed TOCN exhibited no significant difference in mechanical properties and could be used as a proppant for fracturing fluids to improve their stability.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Materials Science, Paper & Wood
Yufei Nan, Diego Gomez-Maldonado, Maria C. C. Iglesias, Daniel C. C. Whitehead, Maria S. S. Peresin
Summary: Cellulose nanomaterial (CNM) and polyethylenimine (PEI) composites have been utilized to create multifunctional hydrogels from soybean hulls. The hydrogels, functionalized with different concentrations of PEI solutions at various pH values, showed promising adsorption efficiency for the removal of methyl blue dyes and Cu(II) ions from water.
Article
Materials Science, Textiles
Sabina Yeasmin, Il Jun Kwon, Dong Jun Kwon, Jungeon Lee, Jeong Hyun Yeum, Byung Chul Ji, Jae Min Park, Seong Baek Yang
Summary: This study successfully prepared a pullulan nanocomposite film with TEMPO cellulose nanofibrils and Ag nanoparticles, which showed good dispersion and uniformity. The film exhibited improved mechanical properties, thermal stability, and water barrier properties, as well as biodegradability and antimicrobial characteristics.
FIBERS AND POLYMERS
(2022)
Article
Materials Science, Multidisciplinary
Rui Liu, Xiang He, Miao Miao, Shaomei Cao, Xin Feng
Summary: Flexible polymeric films with internal porous structures have garnered increasing attention for low dielectric applications. By introducing highly porous metal-organic frameworks into an aramid nanofibers matrix with the aid of carboxylated cellulose nanofibrils, strong, flexible, and ultra-low dielectric films were obtained. The films exhibited excellent thermal stability, mechanical integrity, and UV resistance, making them suitable for microelectronic applications under large deformation conditions.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Applied
Shaohuang Chen, Ning Yue, Mei Cui, Anastasia Penkova, Renliang Huang, Wei Qi, Zhimin He, Rongxin Su
Summary: A novel strategy for direct reuse and extraction recovery of TEMPO in the production of cellulose nanofibrils (CNFs) has been developed, enabling clean and cost-effective production of CNFs with negligible loss of catalyst activity.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Yuxuan Ren, Zhe Ling, Caoxing Huang, Chenhuan Lai, Qiang Yong
Summary: In this study, cellulose films with a sandwich structure were prepared using a surface assembly technique. The films showed enhanced UV-shielding property, hydrophobicity, and mechanical strength through the grafting of L-phenylalanine and the coating of octadecyltrichlorosilane and 4ARM-PEG-NH2. The modified films also exhibited antibacterial activity and efficient oil-water separation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Sabina Yeasmin, Jeong Hyun Yeum, Byung Chul Ji, Jin Hyun Choi, Seong Baek Yang
Summary: Hybrid nanobiocomposite films were prepared by incorporating TOCNs and CNTs into a PULL aqueous solution, resulting in enhanced material properties such as increased crystallinity, higher tensile strength, and improved water barrier properties. The films showed almost complete biodegradability within 64 days and exhibited excellent electrical conductivity, suggesting a promising approach for transforming natural polymers into advanced materials for biosensing and electronics applications.
Review
Chemistry, Multidisciplinary
Meghan E. Lamm, Kai Li, Ji Qian, Lu Wang, Nathalie Lavoine, Reagan Newman, Douglas J. Gardner, Teng Li, Liangbing Hu, Arthur J. Ragauskas, Halil Tekinalp, Vlastimil Kunc, Soydan Ozcan
Summary: The use of cellulose nanofibers in templating shows great promise in controlling the final properties of advanced functional materials, including mechanical strength, porosity, and others.
ADVANCED MATERIALS
(2021)
Article
Polymer Science
Yoojin Kim, Young-Teck Kim, Xiyu Wang, Byungjin Min, Su-il Park
Summary: A new system of TEMPO-oxidized cellulose nanofibrils (TOCNs)/graphene oxide (GO) composite was successfully designed by utilizing TEMPO-mediated oxidation. The dispersion of GO into the matrix of nanofibrillated cellulose (NFC) was improved by a unique process combining high-intensity homogenization and ultrasonication. The resulting bio-nanocomposite exhibited enhanced thermal stability, mechanical properties, and barrier properties.
Article
Chemistry, Multidisciplinary
Shan-Shan Fu, Qiang-Qiang Yuan, Lihua Ma, Zhi-Ming Zhang, Tong-Bu Lu, Song Guo
Summary: A series of TEMPO@PCN-222 composite photocatalysts were developed by coordinating different amount of 4-carboxy-TEMPO with the secondary building units of PCN-222. Visible-light irradiation enables the transfer of photogenerated holes in the highest occupied molecular orbital of PCN-222 to TEMPO, significantly increasing the photosynthesis of bioactive (iso)quinolones. With an outstanding catalytic stability and substrate tolerance, TEMPO@PCN-222 exhibits a yield of 86.7% for 1-methyl-2-quinolinone, over four times higher than PCN-222 (21.4%). This study provides a new route for constructing composite photocatalysts from abundant starting materials for efficient photosynthesis of high value-added chemicals.
Article
Forestry
Zhongguo Wang, Xiong-Fei Zhang, Meili Ding, Jianfeng Yao
Summary: Wood sponges with hierarchical porosity and high mechanical resilience are prepared by selectively removing lignin and grafting amine agents. These amine-grafted wood sponges exhibit a relatively high CO2 uptake, making them promising renewable CO2 capture materials.
WOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Forestry
Yuko Ono, Miyuki Takeuchi, Yaxin Zhou, Akira Isogai
Summary: In this study, TEMPO-oxidized cellulose nanofibrils were successfully prepared with reduced crystallinity and surface defects.
Article
Nanoscience & Nanotechnology
Dawei Xu, Cong Li, Yuqiu Zi, Dafeng Jiang, Fei Qu, Xian-En Zhao
Summary: A new strategy for cholesterol determination was developed using MOF@MnO2 nanocomposites and hybrid nanoflowers, which greatly improved the stability of enzymes and demonstrated good detection performance and specificity. The concentration of cholesterol showed a positive correlation with fluorescence recovery in the range of 10 to 360 μM, with a low detection limit of 1.57 μM.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)