Article
Mechanics
F. Minami, K. Hasegawa
Summary: The impact behavior of a droplet in a liquid pool is crucial in both nature and industry. This study investigates the impact characteristics of droplets with different solubilities in water, providing physical insights into the dynamics of droplet impact in a deep pool.
Review
Polymer Science
Sarah Vanessa Homburg, Anant Patel
Summary: Despite the potential of microalgae as a feedstock for various industries, their production processes are currently uneconomical due to slow growth rates, expensive media, problematic downstream processes, and low cell densities. Entrapment via immobilization in silica hydrogels offers a promising solution to these challenges, allowing continuous processes with protection against shear forces and contaminations. Efforts have been made to improve biocompatibility and, through various methods, enable the proliferation of entrapped microalgae cells. This review provides an overview of entrapment methods in silica hydrogels, specifically for sensitive microalgae.
Review
Medicine, General & Internal
Jin-Ho Jeong, Ji Hye Hwang
Summary: This study aims to evaluate the effectiveness and safety of pharmacopuncture in patients with nerve entrapment syndrome. The systematic review of randomized controlled trials will provide high-quality evidence to determine the efficacy and safety of pharmacopuncture therapy for nerve entrapment syndrome.
Review
Biochemistry & Molecular Biology
Eduardo Silveira Ribeiro, Bruna Silva de Farias, Tito Roberto Sant'Anna Cadaval Junior, Luiz Antonio de Almeida Pinto, Patricia Silva Diaz
Summary: Chitosan-based nanofibers exhibit outstanding properties for enzyme immobilization, enhancing stability and efficiency. Different methods of enzyme immobilization, such as adsorption, cross-linking, and entrapment, each have their own advantages and challenges that need to be addressed. The application of chitosan-based nanofibers in enzyme immobilization offers opportunities to improve catalytic activity and extend the lifetime of enzymes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Engineering, Environmental
Ying Xu, Thomas Curtis, Jan Dolfing, Yonghong Wu, Bruce E. Rittmann
Summary: Research findings suggest that the regulation of N-acyl-homoserine-lactones (AHLs) via quorum sensing signaling can optimize phosphorus (P) entrapment in microbial aggregates, promoting microbial growth and enhancing the community of polyphosphate-accumulating organisms (PAOs) to increase both intra-and extra-cellular P capture.
Article
Biochemistry & Molecular Biology
Aryatara Shakya, Pengfei Liu, Jack Godek, Nicholas W. Mckee, Matthew Dodson, Annadurai Anandhan, Aikseng Ooi, Joe G. N. Garcia, Max Costa, Eli Chapman, Donna D. Zhang
Summary: The study found that p97 is a ubiquitin-targeted ATP-dependent segregase that regulates proteostasis, in addition to other cellular functions. It negatively regulates NRF2 by extracting ubiquitylated NRF2 from the KEAP1-CUL3-RBX1 E3 ubiquitin ligase complex, facilitating proteasomal destruction. The study also identified p97 as an NRF2-target gene that maintains redox homeostasis through a negative feedback loop, and found a positive correlation between NRF2 activation and p97 expression in human cancer patients. Inhibition of both NRF2 and p97 could be a promising treatment strategy for cancer patients.
Article
Green & Sustainable Science & Technology
Felipe Vargas, Marco A. Alsina, Jean-Francois Gaillard, Pablo Pasten, Mauricio Lopez
Summary: Utilizing copper tailings as supplementary cementitious material can help reduce environmental impact, but the leaching of toxic metals, especially copper, remains a concern. Investigating the entrapment mechanisms of copper in the cementitious matrix has shown promising results, such as reducing leaching by decreasing the water-to-binder ratio and promoting the formation of hydration products. Understanding these mechanisms could lead to new strategies for reducing the mobility of toxic elements and increasing the use of copper tailings as a replacement for cement.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Multidisciplinary
Maria J. Lapponi, Mariana B. Mendez, Jorge A. Trelles, Cintia W. Rivero
Summary: This review discusses the current applications of cell immobilization in various biocatalytic purposes, showcasing how different immobilization methodologies can enhance catalyst stability, reusability, and reduce costs in bioprocesses across different industries.
CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yaxin Zheng, Lei Xie, Xiaoru Tie, Lei Cao, Qingyuan Li, Yue Quan, Lingfeng Tang, Yang Li
Summary: A click reaction-mediated loading procedure was developed using an enzyme-sensitive maleimide (MAL) tag to ferry chemotherapeutics into liposomes. This method allows efficient encapsulation of hydrophobic drugs within liposomes, with subsequent slow release and rapid conversion into active drugs for enhanced antitumor efficacy. It is a remote drug loading strategy suitable for industrial production, offering potential as a universal drug loading strategy for liposomal formulations of chemotherapeutics.
MATERIALS HORIZONS
(2022)
Editorial Material
Hematology
Andreas Greinacher, Falk Nimmerjahn
Summary: In this article published in Blood, Wang et al. demonstrate that the severe adverse effect of vaccine-induced immune thrombotic thrombocytopenia (VITT) is caused by structurally similar antibodies. Their findings suggest that VITT is the result of rapid clonal expansion of a few B-cell clones, leading to the production of a few closely related antibodies. Furthermore, the gene encoding the variable region of the immunoglobulin G (IgG) light chain appears to have the same polymorphism (IGLV3-21*02) in all patients investigated.
Article
Materials Science, Multidisciplinary
Gang Li, Chunxiao Lu, Meijuan Gan, Qiangqiang Wang, Shengping He
Summary: This study investigated the effects of clogging on the flow field and slag entrainment during continuous casting. The results showed that the flow field changed gradually as the clogging grew, and the entrainment of slag became more severe.
METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Neelakandan Tamilarasan, Begum M. Yasmin, Posina Anitha, Hani Umme, Wan Hee Cheng, Sellapan Mohan, Sundarapandian Ramkanth, Ashok Kumar Janakiraman
Summary: This study optimized and evaluated proanthocyanidin-containing transferosomal transdermal gels, and the results showed that the optimized transferosomal gel had good penetration ability and stability.
Review
Medicine, General & Internal
Wei-Ting Wu, Ke-Vin Chang, Yu-Chun Hsu, Yuan-Yuan Tsai, Kamal Mezian, Vincenzo Ricci, Levent Ozcakar
Summary: Ultrasound is a valuable tool for imaging peripheral nerve lesions in the wrist region, with a particular focus on common pathologies such as carpal tunnel and Guyon's canal syndromes. This article provides a comprehensive overview of scanning techniques, pathology, and guided-injection methods for these nerve entrapments. The review elaborates on various nerves in the wrist and hand and includes detailed ultrasound images to illustrate the techniques.
Review
Medicine, Research & Experimental
Zeynab Kohandel, Tahereh Farkhondeh, Michael Aschner, Saeed Samarghandian
Summary: Astaxanthin (ATX) is a red pigment carotenoid found in shrimp, salmon, crab, and asteroidean, with proven antioxidant efficacy. Nrf2 plays a crucial role in mediating the various protective effects of ATX.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Peripheral Vascular Disease
Arjun Jayaraj, Peter Gloviczki, Audra A. Duncan, Manju Kalra, Gustavo S. Oderich, Randall R. DeMartino, Thomas C. Bower
Summary: The study evaluated the current classification system for popliteal entrapment syndrome and found that it only accurately captured 64% of cases. A new classification system was developed that captured 100% of cases, indicating the need for a more inclusive classification system.
Review
Biochemical Research Methods
Gregory Tombline, Jonathan Gigas, Nicholas Macoretta, Max Zacher, Stephan Emmrich, Yang Zhao, Andrei Seluanov, Vera Gorbunova
Article
Biochemistry & Molecular Biology
Varun Kumar, Raman Agrawal, Aparamita Pandey, Stefan Kopf, Manuel Hoeffgen, Serap Kaymak, Obul Reddy Bandapalli, Vera Gorbunova, Andrei Seluanov, Marcus A. Mall, Stephan Herzig, Peter P. Nawroth
Article
Multidisciplinary Sciences
Masaki Takasugi, Denis Firsanov, Gregory Tombline, Hanbing Ning, Julia Ablaeva, Andrei Seluanovg, Vera Gorbunova
NATURE COMMUNICATIONS
(2020)
Article
Cell Biology
Sarallah Rezazadeh, David Yang, Seyed Ali Biashad, Denis Firsanov, Masaki Takasugi, Michael Gilbert, Gregory Tombline, Natarajan Bhanu, Benjamin A. Garcia, Andrei Seluanov, Vera Gorbunova
Article
Biochemical Research Methods
Kyle Swovick, Denis Firsanov, Kevin A. Welle, Jennifer R. Hryhorenko, John P. Wise, Craig George, Todd L. Sformo, Andrei Seluanov, Vera Gorbunova, Sina Ghaemmaghami
Summary: The study found that organismal life span is negatively correlated with protein turnover rates. Long-lived species have slower rates of protein turnover but can tolerate protein misfolding stress more effectively.
MOLECULAR & CELLULAR PROTEOMICS
(2021)
Article
Multidisciplinary Sciences
Adeline Augereau, Marco Mariotti, Melanie Pousse, Doria Filipponi, Frederick Libert, Benjamin Beck, Vera Gorbunova, Eric Gilson, Vadim N. Gladyshev
Summary: The study reveals that the naked mole rat TRF1 supports maximal glycolytic capacity under low oxygen, showing increased nuclear localization and association with telomeres, and protecting them from replicative stress. The evolutionary gain of metabolic function in naked mole rat TRF1 is attributed to specific amino acid changes in the protein's homodimerization domain, while it also accelerates telomere shortening. This evolutionary strategy highlights an adaptation of telomere biology for metabolic control in extreme environments.
Article
Cell Biology
Joanna Kacprzyk, Andrea G. Locatelli, Graham M. Hughes, Zixia Huang, Michael Clarke, Vera Gorbunova, Carlotta Sacchi, Gavin S. Stewart, Emma C. Teeling
Summary: Research shows that in bats, the expression of autophagy-related genes increases with age, a phenomenon not commonly seen in other mammals. By analyzing the bat genome, key genes that influence the increase in autophagy signaling have been identified, which may contribute to extending the bats' healthspan.
Article
Cell Biology
Vera Gorbunova, Masaki Takasugi, Andrei Seluanov
Article
Cell Biology
Taketo Taguchi, Alexander Kotelsky, Masaki Takasugi, Martin Chang, Zhonghe Ke, Megan Betancourt, Mark R. Buckley, Michael Zuscik, Andrei Seluanov, Vera Gorbunova
Review
Endocrinology & Metabolism
Zhengdong D. Zhang, Sofiya Milman, Jhih-Rong Lin, Shayne Wierbowski, Haiyuan Yu, Nir Barzilai, Vera Gorbunova, Warren C. Ladiges, Laura J. Niedernhofer, Yousin Suh, Paul D. Robbins, Jan Vijg
