NK1R antagonist decreases inflammation and metastasis of breast carcinoma cells metastasized to liver but not to brain; phenotype-dependent therapeutic and toxic consequences

Secretomes reveal several novel proteins as well as TGF-β1 as the top upstream regulator of metastatic process in breast cancer

(2018) Nuray Erin et al.   BREAST CANCER RESEARCH AND TREATMENT

Truncation of neurokinin-1 receptor-Negative regulation of substance P signaling

(2018) Sergei Spitsin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CD200fc enhances anti-tumoral immune response and inhibits visceral metastasis of breast carcinoma

(2018) Nuray Erin et al.   Oncotarget

Differential consequences of neurokinin receptor 1 and 2 antagonists in metastatic breast carcinoma cells; Effects independent of Substance P

(2018) Esra Nizam et al.   BIOMEDICINE & PHARMACOTHERAPY

Ovarian cancer stem cell: A potential therapeutic target for overcoming multidrug resistance

(2018) Aynaz Mihanfar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Activation of neuroimmune pathways increases therapeutic effects of radiotherapy on poorly differentiated breast carcinoma

(2015) Nuray Erin et al.   BRAIN BEHAVIOR AND IMMUNITY

The substance P/NK-1 receptor system: NK-1 receptor antagonists as anti-cancer drugs

(2015) Miguel Muñoz et al.   JOURNAL OF BIOSCIENCES

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-17A and its homologs IL-25/IL-17E recruit the c-RAF/S6 kinase pathway and the generation of pro-oncogenic LMW-E in breast cancer cells

(2015) Sarah Mombelli et al.   Scientific Reports

The correlations between IL-17 vs. Th17 cells and cancer patient survival: a systematic review

(2015) Simone Punt et al.   OncoImmunology

Pathogenesis of Breast Cancer Metastasis to Brain: a Comprehensive Approach to the Signaling Network

(2014) Bahrami Tayyeb et al.   MOLECULAR NEUROBIOLOGY

Bidirectional effect of CD200 on breast cancer development and metastasis, with ultimate outcome determined by tumor aggressiveness and a cancer-induced inflammatory response

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Differential characteristics of heart, liver, and brain metastatic subsets of murine breast carcinoma

(2013) Nuray Erin et al.   BREAST CANCER RESEARCH AND TREATMENT

Roles of full-length and truncated neurokinin-1 receptors on tumor progression and distant metastasis in human breast cancer

(2013) Yunli Zhou et al.   BREAST CANCER RESEARCH AND TREATMENT

Interleukin-17: A Promoter in Colorectal Cancer Progression

(2013) Dang Wu et al.   Clinical & Developmental Immunology

Cytokine patterns in patients with cancer: a systematic review

(2013) Bodo E Lippitz   LANCET ONCOLOGY

Role of neurokinin-1 receptor in the initiation and maintenance of skin chronic inflammatory diseases

(2011) Sherrie J. Divito et al.   IMMUNOLOGIC RESEARCH

A New Frontier in the Treatment of Cancer: NK-1 Receptor Antagonists

(2010) M. Munoz et al.   CURRENT MEDICINAL CHEMISTRY

TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype

(2010) Gianluca Storci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Substance P inhibits natural killer cell cytotoxicity through the neurokinin-1 receptor

(2010) Linda Monaco-Shawver et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Altered gene expression in breast cancer liver metastases

(2008) Nuray Erin et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

The NK-1 Receptor Is Expressed in Human Primary Gastric and Colon Adenocarcinomas and Is Involved in the Antitumor Action of L-733,060 and the Mitogenic Action of Substance P on Human Gastrointestinal Cancer Cell Lines

(2008) Marisa Rosso et al.   TUMOR BIOLOGY